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FältnamnIndikatorerMetadata
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003SwePub
008230123s2023 | |||||||||||000 ||eng|
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009oai:prod.swepub.kib.ki.se:150888678
009oai:prod.swepub.kib.ki.se:154941534
0247 a https://lup.lub.lu.se/record/891a4b65-e365-4ac6-9a22-bd6f1074d1322 URI
0247 a https://doi.org/10.1002/alz.127982 DOI
0247 a http://kipublications.ki.se/Default.aspx?queryparsed=id:2362093792 URI
0247 a http://kipublications.ki.se/Default.aspx?queryparsed=id:1508886782 URI
0247 a http://kipublications.ki.se/Default.aspx?queryparsed=id:1549415342 URI
040 a (SwePub)lud (SwePub)kid (SwePub)kid (SwePub)ki
041 a engb eng
042 9 SwePub
072 7a art2 swepub-publicationtype
072 7a ref2 swepub-contenttype
1001 a Festari, Cristinau Centro San Giovanni di Dio Fatebenefratelli4 aut
2451 0a European consensus for the diagnosis of MCI and mild dementia : Preparatory phase
264 c 2022-10-09
264 1b Wiley,c 2023
520 a Introduction: Etiological diagnosis of neurocognitive disorders of middle-old age relies on biomarkers, although evidence for their rational use is incomplete. A European task force is defining a diagnostic workflow where expert experience fills evidence gaps for biomarker validity and prioritization. We report methodology and preliminary results. Methods: Using a Delphi consensus method supported by a systematic literature review, 22 delegates from 11 relevant scientific societies defined workflow assumptions. Results: We extracted diagnostic accuracy figures from literature on the use of biomarkers in the diagnosis of main forms of neurocognitive disorders. Supported by this evidence, panelists defined clinical setting (specialist outpatient service), application stage (MCI-mild dementia), and detailed pre-assessment screening (clinical-neuropsychological evaluations, brain imaging, and blood tests). Discussion: The Delphi consensus on these assumptions set the stage for the development of the first pan-European workflow for biomarkers’ use in the etiological diagnosis of middle-old age neurocognitive disorders at MCI-mild dementia stages. Highlights: Rational use of biomarkers in neurocognitive disorders lacks consensus in Europe. A consensus of experts will define a workflow for the rational use of biomarkers. The diagnostic workflow will be patient-centered and based on clinical presentation. The workflow will be updated as new evidence accrues.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Neurologi0 (SwePub)302072 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Neurology0 (SwePub)302072 hsv//eng
653 a consensus
653 a Delphi procedure
653 a etiological diagnosis
653 a imaging
653 a major neurocognitive disorder
653 a MCI
653 a mild dementia – biomarker
653 a neurocognitive disorders
7001 a Massa, Federicou University of Genoa4 aut
7001 a Cotta Ramusino, Matteou University of Pavia4 aut
7001 a Gandolfo, Federicau Galliera Hospital, Genova4 aut
7001 a Nicolosi, Valentinau Ospedale Magalini, Villafranca di Verona4 aut
7001 a Orini, Stefaniau Centro San Giovanni di Dio Fatebenefratelli,University of Brescia4 aut
7001 a Aarsland, Dagu Karolinska Institutet4 aut
7001 a Agosta, Federicau San Raffaele Hospital,Vita-Salute San Raffaele University4 aut
7001 a Babiloni, Claudiou Sapienza University of Rome4 aut
7001 a Boada, Mercèu International University of Catalonia,CIBER Enfermedades Neurodegenerativas (CIBERNED)4 aut
7001 a Borroni, Barbarau Spedali Civili Di Brescia,University of Brescia4 aut
7001 a Cappa, Stefanou Institute for Advanced Studies (IUSS), Pavia4 aut
7001 a Dubois, Brunou Pitié-Salpêtrière University Hospital4 aut
7001 a Frederiksen, Kristian S.u University of Copenhagen4 aut
7001 a Froelich, Lutzu Heidelberg University4 aut
7001 a Garibotto, Valentinau University of Geneva Medical School,Geneva University Hospital4 aut
7001 a Georges, Jeanu Alzheimer Europe4 aut
7001 a Haliassos, Alexanderu International Federation of Clinical Chemistry and Laboratory Medicine (IFCC)4 aut
7001 a Hansson, Oskaru Lund University,Lunds universitet,Klinisk minnesforskning,Forskargrupper vid Lunds universitet,Clinical Memory Research,Lund University Research Groups,Skåne University Hospital4 aut0 (Swepub:lu)mphy-ohn
7001 a Jessen, Franku University of Cologne,German Center for Neurodegenerative Diseases (DZNE), Bonn4 aut
7001 a Kamondi, Anitau National Institute of Mental Health, Neurology and Neurosurgery, Budapest,International Federation of Clinical Neurophysiology (IFCN)4 aut
7001 a Kessels, Roy P.C.u Radboud University Medical Center4 aut
7001 a Morbelli, Silviau Ospedale Policlinico San Martino,University of Genoa4 aut
7001 a O'Brien, John T.u University of Cambridge4 aut
7001 a Otto, Markusu Martin-Luther-Universität Halle-Wittenberg4 aut
7001 a Perret-Liaudet, Armandu Lyon Civil Hospital / Hospices Civils de Lyon4 aut
7001 a Pizzini, Francesca B.u University Hospital Verona4 aut
7001 a Ritchie, Craig W.u University of Edinburgh4 aut
7001 a Scheltens, Philipu Vrije Universiteit Amsterdam4 aut
7001 a Vandenbulcke, Mathieuu University Hospitals Leuven4 aut
7001 a Vanninen, Ritvau University of Eastern Finland4 aut
7001 a Verhey, Fransu Maastricht University4 aut
7001 a Vernooij, Meike W.u Erasmus University Medical Center4 aut
7001 a Yousry, Tareku University College London Hospital4 aut
7001 a Van Der Flier, Wiesje M.u Vrije Universiteit Amsterdam4 aut
7001 a Nobili, Flaviou University of Genoa,Ospedale Policlinico San Martino4 aut
7001 a Frisoni, Giovanni B.u Geneva University Hospital,University of Geneva4 aut
7102 a Centro San Giovanni di Dio Fatebenefratellib University of Genoa4 org
7730 t Alzheimer's and Dementiad : Wileyg 19:5, s. 1729-1741q 19:5<1729-1741x 1552-5260x 1552-5279
8564 u http://dx.doi.org/10.1002/alz.12798x freey FULLTEXT
8564 8u https://lup.lub.lu.se/record/891a4b65-e365-4ac6-9a22-bd6f1074d132
8564 8u https://doi.org/10.1002/alz.12798
8564 8u http://kipublications.ki.se/Default.aspx?queryparsed=id:236209379
8564 8u http://kipublications.ki.se/Default.aspx?queryparsed=id:150888678
8564 8u http://kipublications.ki.se/Default.aspx?queryparsed=id:154941534

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