WFRF:(Jensen Urstad M)
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Heart rate variability in healthy subjects is related to age and gender.
- Jensen-Urstad, K (författare)
- Storck, N (författare)
-
- Bouvier, F (författare)
- Karolinska Institutet
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- Lindblad, L E (författare)
- Jensen-Urstad, M (författare)
- JensenUrstad, K (författare)
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- (creator_code:org_t)
- 1997
- 1997
- Engelska.
- Ingår i: Acta Physiologica Scandinavica. - 0001-6772 .- 1365-201X. ; 160:3, s. 235-41
- Tidskriftsartikel (refereegranskat)
Abstract
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Stäng
- The effects of age and gender on heart rate variability as measured by spectral and time domain analysis of 24 h ECG recordings were evaluated in 101 healthy subjects, 49 men and 52 women (20-69 years of age). In the frequency domain, total power, very low-frequency power, low-frequency power and high-frequency power were negatively correlated to age (P < 0.001 for all variables). Total power decreased by 30% between 20-29 and 60-69 years of age. In the time domain, SDNN-index, the mean of the standard deviations of all normal R-R intervals for all 5 min segments of a 24 h ECG recording, was negatively correlated to age (P < 0.001). Total power, very low-frequency power, low-frequency power and the low-frequency/high-frequency ratio were lower in women (P < 0.05, P < 0.05, P < 0.01 and P < 0.01), although the absolute differences were much smaller than for age. There was a pronounced circadian variation; at night total power increased in all age groups (P < 0.01). The results show that age, and to a lesser degree gender, are important determinants of heart rate variability in healthy subjects. Heart rate variability is a valuable tool for risk stratification in cardiovascular disease, but the physiological effects of ageing, with diminishing heart rate variability in older age groups, must also be taken into account.
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- Jensen-Urstad, K
- Storck, N
- Bouvier, F
- Ericson, Mats
- Lindblad, L E
- Jensen-Urstad, M
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- JensenUrstad, K
- JensenUrstad, M
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