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Sökning: WFRF:(Konishi Tsuyoshi) > Stoma-free survival...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00008077naa a2200745 4500
001oai:DiVA.org:umu-217021
003SwePub
008231124s2023 | |||||||||||000 ||eng|
009oai:prod.swepub.kib.ki.se:237819790
009oai:prod.swepub.kib.ki.se:154917274
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-2170212 URI
0247 a https://doi.org/10.1093/bjs/znad3112 DOI
0247 a http://kipublications.ki.se/Default.aspx?queryparsed=id:2378197902 URI
0247 a http://kipublications.ki.se/Default.aspx?queryparsed=id:1549172742 URI
040 a (SwePub)umud (SwePub)kid (SwePub)ki
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Greijdanus, Nynke G.u Department of Surgery, Radboud University Medical Centre, Radboud Institute for Health Sciences, Nijmegen, Netherlands4 aut
2451 0a Stoma-free survival after anastomotic leak following rectal cancer resection :b worldwide cohort of 2470 patients
264 1b Oxford University Press,c 2023
338 a electronic2 rdacarrier
520 a BACKGROUND: The optimal treatment of anastomotic leak after rectal cancer resection is unclear. This worldwide cohort study aimed to provide an overview of four treatment strategies applied.METHODS: Patients from 216 centres and 45 countries with anastomotic leak after rectal cancer resection between 2014 and 2018 were included. Treatment was categorized as salvage surgery, faecal diversion with passive or active (vacuum) drainage, and no primary/secondary faecal diversion. The primary outcome was 1-year stoma-free survival. In addition, passive and active drainage were compared using propensity score matching (2 : 1).RESULTS: Of 2470 evaluable patients, 388 (16.0 per cent) underwent salvage surgery, 1524 (62.0 per cent) passive drainage, 278 (11.0 per cent) active drainage, and 280 (11.0 per cent) had no faecal diversion. One-year stoma-free survival rates were 13.7, 48.3, 48.2, and 65.4 per cent respectively. Propensity score matching resulted in 556 patients with passive and 278 with active drainage. There was no statistically significant difference between these groups in 1-year stoma-free survival (OR 0.95, 95 per cent c.i. 0.66 to 1.33), with a risk difference of -1.1 (95 per cent c.i. -9.0 to 7.0) per cent. After active drainage, more patients required secondary salvage surgery (OR 2.32, 1.49 to 3.59), prolonged hospital admission (an additional 6 (95 per cent c.i. 2 to 10) days), and ICU admission (OR 1.41, 1.02 to 1.94). Mean duration of leak healing did not differ significantly (an additional 12 (-28 to 52) days).CONCLUSION: Primary salvage surgery or omission of faecal diversion likely correspond to the most severe and least severe leaks respectively. In patients with diverted leaks, stoma-free survival did not differ statistically between passive and active drainage, although the increased risk of secondary salvage surgery and ICU admission suggests residual confounding.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kirurgi0 (SwePub)302122 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Surgery0 (SwePub)302122 hsv//eng
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Cancer och onkologi0 (SwePub)302032 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cancer and Oncology0 (SwePub)302032 hsv//eng
653 a Anastomosis
653 a Surgical
653 a Anastomotic Leak
653 a Cohort Studies
653 a Humans
653 a Rectal Neoplasms
653 a Rectum
653 a Retrospective Studies
7001 a Wienholts, Kiedou Department of Surgery, Amsterdam University Medical Centres, University of Amsterdam, Amsterdam, Netherlands; Cancer Centre Amsterdam, Treatment and Quality of Life, Amsterdam, Netherlands; Cancer Centre Amsterdam, Amsterdam, Netherlands4 aut
7001 a Ubels, Sanderu Department of Surgery, Radboud University Medical Centre, Radboud Institute for Health Sciences, Nijmegen, Netherlands4 aut
7001 a Talboom, Kevinu Department of Surgery, Amsterdam University Medical Centres, University of Amsterdam, Amsterdam, Netherlands; Cancer Centre Amsterdam, Treatment and Quality of Life, Amsterdam, Netherlands; Cancer Centre Amsterdam, Amsterdam, Netherlands4 aut
7001 a Hannink, Gerjonu Department of Medical Imaging, Radboud University Medical Centre, Radboud Institute for Health Sciences, Nijmegen, Netherlands4 aut
7001 a Wolthuis, Albertu Department of Surgery, UZ Leuven, Leuven, Belgium4 aut
7001 a de Lacy, F Borjau Gastrointestinal Surgery Department, Hospital Clinic of Barcelona, University of Barcelona, Barcelona, Spain4 aut
7001 a Lefevre, Jérémie Hu Department of Digestive Surgery, Sorbonne Université, AP-HP, Hôpital Saint Antoine, Paris, France4 aut
7001 a Solomon, Michaelu Department of Surgery, University of Sydney Central Clinical School, Camperdown, NSW, Australia4 aut
7001 a Frasson, Matteou Department of Surgery, Valencia University Hospital La Fe, Valencia, Spain4 aut
7001 a Rotholtz, Nicolasu Department of Surgery, Hospital Alemán, Buenos Aires, Argentina4 aut
7001 a Denost, Quentinu Clinique Tivoli, Bordeaux, France4 aut
7001 a Perez, Rodrigo O.u Colorectal Surgery, Hospital Alemão Oswaldo Cruz, São Paulo, Brazil4 aut
7001 a Konishi, Tsuyoshiu Department of Colon and Rectal Surgery, University of Texas MD Anderson Cancer Center, TX, Anderson, United States4 aut
7001 a Panis, Yvesu Colorectal Surgery Centre, Groupe Hospitalier Privé Ambroise Paré-Hartmann, Neuilly Seine, France4 aut
7001 a Rutegård, Martin,d 1982-u Umeå universitet,Institutionen för kirurgisk och perioperativ vetenskap,Wallenberg centrum för molekylär medicin vid Umeå universitet (WCMM)4 aut0 (Swepub:umu)maru0039
7001 a Hompes, Roelu Department of Surgery, Amsterdam University Medical Centres, University of Amsterdam, Amsterdam, Netherlands; Cancer Centre Amsterdam, Treatment and Quality of Life, Amsterdam, Netherlands; Cancer Centre Amsterdam, Amsterdam, Netherlands4 aut
7001 a Rosman, Camielu Department of Surgery, Radboud University Medical Centre, Radboud Institute for Health Sciences, Nijmegen, Netherlands4 aut
7001 a van Workum, Fransu Department of Surgery, Canisius Wilhelmina Hospital, Nijmegen, Netherlands4 aut
7001 a Tanis, Pieter J.u Department of Surgery, Amsterdam University Medical Centres, University of Amsterdam, Amsterdam, Netherlands; Cancer Centre Amsterdam, Treatment and Quality of Life, Amsterdam, Netherlands; Cancer Centre Amsterdam, Amsterdam, Netherlands; Erasmus Medical Centre, Department of Surgical Oncology and Gastrointestinal Surgery, Rotterdam, Netherlands4 aut
7001 a de Wilt, Johannes H Wu Department of Surgery, Radboud University Medical Centre, Radboud Institute for Health Sciences, Nijmegen, Netherlands4 aut
7001 a Tsuyoshi, T4 aut
7102 a Department of Surgery, Radboud University Medical Centre, Radboud Institute for Health Sciences, Nijmegen, Netherlandsb Department of Surgery, Amsterdam University Medical Centres, University of Amsterdam, Amsterdam, Netherlands; Cancer Centre Amsterdam, Treatment and Quality of Life, Amsterdam, Netherlands; Cancer Centre Amsterdam, Amsterdam, Netherlands4 org
7730 t British Journal of Surgeryd : Oxford University Pressg 110:12, s. 1863-1876q 110:12<1863-1876x 0007-1323x 1365-2168
8564 u https://doi.org/10.1093/bjs/znad311y Fulltext
8564 u https://umu.diva-portal.org/smash/get/diva2:1814369/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-217021
8564 8u https://doi.org/10.1093/bjs/znad311
8564 8u http://kipublications.ki.se/Default.aspx?queryparsed=id:237819790
8564 8u http://kipublications.ki.se/Default.aspx?queryparsed=id:154917274

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