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Incidence, risk fac...
Incidence, risk factors and 90-day mortality of patients with acute kidney injury in Finnish intensive care units : the FINNAKI study
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Nisula, Sara (author)
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Kaukonen, Kirsi-Maija (author)
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Vaara, Suvi T (author)
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Korhonen, Anna-Maija (author)
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Poukkanen, Meri (author)
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Karlsson, Sari (author)
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Haapio, Mikko (author)
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Inkinen, Outi (author)
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Parviainen, Ilkka (author)
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Suojaranta-Ylinen, Raili (author)
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Laurila, Jouko J (author)
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- Tenhunen, Jyrki (author)
- Department of Intensive Care Medicine, Tampere University Hospital, Tampere, Finland
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Reinikainen, Matti (author)
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Ala-Kokko, Tero (author)
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Ruokonen, Esko (author)
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Kuitunen, Anne (author)
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Pettilä, Ville (author)
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(creator_code:org_t)
- 2013-01-05
- 2013
- English.
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In: Intensive Care Medicine. - : Springer Science and Business Media LLC. - 0342-4642 .- 1432-1238. ; 39:3, s. 420-428
- Related links:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
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- PURPOSEWe aimed to determine the incidence, risk factors and outcome of acute kidney injury (AKI) in Finnish ICUs.METHODSThis prospective, observational, multi-centre study comprised adult emergency admissions and elective patients whose stay exceeded 24 h during a 5-month period in 17 Finnish ICUs. We defined AKI first by the Acute Kidney Injury Network (AKIN) criteria supplemented with a baseline creatinine and second with the Kidney Disease: Improving Global Outcomes (KDIGO) criteria. We screened the patients' AKI status and risk factors for up to 5 days.RESULTSWe included 2,901 patients. The incidence (95 % confidence interval) of AKI was 39.3 % (37.5-41.1 %). The incidence was 17.2 % (15.8-18.6 %) for stage 1, 8.0 % (7.0-9.0 %) for stage 2 and 14.1 % (12.8-15.4 %) for stage 3 AKI. Of the 2,901 patients 296 [10.2 % (9.1-11.3 %)] received renal replacement therapy. We received an identical classification with the new KDIGO criteria. The population-based incidence (95 % CI) of ICU-treated AKI was 746 (717-774) per million population per year (reference population: 3,671,143, i.e. 85 % of the Finnish adult population). In logistic regression, pre-ICU hypovolaemia, diuretics, colloids and chronic kidney disease were independent risk factors for AKI. Hospital mortality (95 % CI) for AKI patients was 25.6 % (23.0-28.2 %) and the 90-day mortality for AKI patients was 33.7 % (30.9-36.5 %). All AKIN stages were independently associated with 90-day mortality.CONCLUSIONSThe incidence of AKI in the critically ill in Finland was comparable to previous large multi-centre ICU studies. Hospital mortality (26 %) in AKI patients appeared comparable to or lower than in other studies.
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Nisula, Sara
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Kaukonen, Kirsi- ...
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Vaara, Suvi T
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Korhonen, Anna-M ...
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Poukkanen, Meri
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Karlsson, Sari
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show more...
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Haapio, Mikko
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Inkinen, Outi
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Parviainen, Ilkk ...
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Suojaranta-Yline ...
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Laurila, Jouko J
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Tenhunen, Jyrki
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Reinikainen, Mat ...
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Ala-Kokko, Tero
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Ruokonen, Esko
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Kuitunen, Anne
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Pettilä, Ville
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Intensive Care M ...
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Uppsala University