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The Development of Highly Sensitive and Selective Immunosensor Based on Antibody Immobilized ZnO Nanorods for the Detection of D-Dimer
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- Hussain Ibupoto, Zafar (author)
- Linköpings universitet,Fysik och elektroteknik,Tekniska högskolan
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- Mitrou, Nikolaos (author)
- University of Athens, Greece
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- Nikoleli, Georgia-Paraskevi (author)
- National Technical University of Athens, Greece
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- (creator_code:org_t)
- 2014-01-30
- 2014
- English.
- In: Electroanalysis. - : Wiley-VCH Verlag. - 1040-0397 .- 1521-4109. ; 26:2, s. 292-298
- Journal article (peer-reviewed)
Abstract
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- ZnO nanorods were grown on gold coated glass substrate by low temperature aqueous chemical growth method. Scanning electron microscopy (SEM) and X-ray diffraction (XRD) techniques were used for the characterization of ZnO nanorods. ZnO nanorods are highly dense, uniform, well aligned and perpendicular-oriented to the substrate. ZnO nanorods exhibited good crystal quality. The well aligned ZnO nanorods were potentially used for the development of selective and sensitive immunosensor for the detection of D-dimer by immobilizing antibody on stabilized lipid films. The ZnO nanorods based immunosensor responded to a wide range of D-dimer concentrations with fast response time of ca. 20s.
Keyword
- ZnO nanorods; D-Dimer; Immunosensors; Potentiometric technique
- TECHNOLOGY
- TEKNIKVETENSKAP
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- ref (subject category)
- art (subject category)
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