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Sökning: WFRF:(Slart Riemer H. J. A.) > (2022) > Detecting the vulne...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00005312naa a2200709 4500
001oai:lup.lub.lu.se:898f7f36-b640-458f-a3a8-5489ea4d5ce3
003SwePub
008221010s2022 | |||||||||||000 ||eng|
0247 a https://lup.lub.lu.se/record/898f7f36-b640-458f-a3a8-5489ea4d5ce32 URI
0247 a https://doi.org/10.2459/JCM.00000000000013142 DOI
040 a (SwePub)lu
041 a engb eng
042 9 SwePub
072 7a art2 swepub-publicationtype
072 7a ref2 swepub-contenttype
1001 a Gargani, Luna4 aut
2451 0a Detecting the vulnerable carotid plaque : The Carotid Artery Multimodality imaging Prognostic study design
264 1c 2022
300 a 8 s.
520 a BackgroundCarotid artery disease is highly prevalent and a main cause of ischemic stroke and vascular dementia. There is a paucity of information on predictors of serious vascular events. Besides percentage diameter stenosis, international guidelines also recommend the evaluation of qualitative characteristics of carotid artery disease as a guide to treatment, but with no agreement on which qualitative features to assess. This inadequate knowledge leads to a poor ability to identify patients at risk, dispersion of medical resources, and unproven use of expensive and resource-consuming techniques, such as magnetic resonance imaging, positron emission tomography, and computed tomography.ObjectivesThe Carotid Artery Multimodality imaging Prognostic (CAMP) study will: prospectively determine the best predictors of silent and overt ischemic stroke and vascular dementia in patients with asymptomatic subcritical carotid artery disease by identifying the noninvasive diagnostic features of the 'vulnerable carotid plaque'; assess whether 'smart' use of low-cost diagnostic methods such as ultrasound-based evaluations may yield at least the same level of prospective information as more expensive techniques.Study designWe will compare the prognostic/predictive value of all proposed techniques with regard to silent or clinically manifest ischemic stroke and vascular dementia. The study will include ≥300 patients with asymptomatic, unilateral, intermediate degree (40-60% diameter) common or internal carotid artery stenosis detected at carotid ultrasound, with a 2-year follow-up. The study design has been registered on Clinicaltrial.gov on December 17, 2020 (ID number NCT04679727).
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kardiologi0 (SwePub)302062 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cardiac and Cardiovascular Systems0 (SwePub)302062 hsv//eng
653 a atherosclerosis
653 a carotid artery disease
653 a carotid artery plaque
653 a carotid ultrasound
653 a magnetic resonance imaging
653 a stroke
653 a vascular dementia
653 a vascular imaging
7001 a Baldini, Matteou University of Pisa4 aut
7001 a Berchiolli, Raffaellau University of Pisa4 aut
7001 a Bort, Ida Rebeccau University of Pisa4 aut
7001 a Casolo, Giancarlo4 aut
7001 a Chiappino, Dante4 aut
7001 a Cosottini, Mircou University of Pisa4 aut
7001 a D'Angelo, Gennaro4 aut
7001 a De Santis, Mariellau University of Pisa4 aut
7001 a Erba, Paolau University Medical Center Groningen,University of Pisa4 aut
7001 a Fabiani, Iacopo4 aut
7001 a Fabiani, Plinio4 aut
7001 a Gabbriellini, Ilariau University of Pisa4 aut
7001 a Galeotti, Gian Giacomou University of Pisa4 aut
7001 a Ghicopulos, Ireneu University of Pisa4 aut
7001 a Goncalves, Isabelu Lund University,Lunds universitet,Kardiovaskulär forskning - translationella studier,Forskargrupper vid Lunds universitet,Cardiovascular Research - Translational Studies,Lund University Research Groups,Skåne University Hospital4 aut0 (Swepub:lu)medf-igo
7001 a Lapi, Simoneu University Hospital of Pisa4 aut
7001 a Masini, Gabrieleu University of Pisa4 aut
7001 a Morizzo, Carmelau University of Pisa4 aut
7001 a Napoli, Viniciou University Hospital of Pisa4 aut
7001 a Nilsson, Janu Lund University,Lunds universitet,Kardiovaskulär forskning - immunitet och ateroskleros,Forskargrupper vid Lunds universitet,Cardiovascular Research - Immunity and Atherosclerosis,Lund University Research Groups,Skåne University Hospital4 aut0 (Swepub:lu)medf-jni
7001 a Orlandi, Giovanniu University of Pisa4 aut
7001 a Palombo, Carlou University of Pisa4 aut
7001 a Pieraccini, Francesco4 aut
7001 a Ricci, Stefanou University of Florence4 aut
7001 a Siciliano, Gabrieleu University of Pisa4 aut
7001 a Slart, Riemer H.J.A.u University of Twente,University Medical Center Groningen4 aut
7001 a De Caterina, Raffaeleu University of Pisa4 aut
7102 a University of Pisab University Medical Center Groningen4 org
7730 t Journal of Cardiovascular Medicineg 23:7, s. 466-473q 23:7<466-473x 1558-2027
8564 u http://dx.doi.org/10.2459/JCM.0000000000001314y FULLTEXT
8564 8u https://lup.lub.lu.se/record/898f7f36-b640-458f-a3a8-5489ea4d5ce3
8564 8u https://doi.org/10.2459/JCM.0000000000001314

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