Sökning: WFRF:(Sundaram Venkataseshan) > Systematic review a...
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000 | 06023naa a2200709 4500 | |
001 | oai:lup.lub.lu.se:d41d6a33-bf6b-444f-a255-16b63cef2227 | |
003 | SwePub | |
008 | 200420s2020 | |||||||||||000 ||eng| | |
024 | 7 | a https://lup.lub.lu.se/record/d41d6a33-bf6b-444f-a255-16b63cef22272 URI |
024 | 7 | a https://doi.org/10.1136/bmjopen-2019-0345952 DOI |
040 | a (SwePub)lu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a for2 swepub-publicationtype |
072 | 7 | a ref2 swepub-contenttype |
100 | 1 | a Seidler, Anna Leneu University of Sydney4 aut |
245 | 1 0 | a Systematic review and network meta-analysis with individual participant data on cord management at preterm birth (iCOMP) : Study protocol |
264 | c 2020-03-29 | |
264 | 1 | b BMJ,c 2020 |
520 | a Introduction: Timing of cord clamping and other cord management strategies may improve outcomes at preterm birth. However, it is unclear whether benefits apply to all preterm subgroups. Previous and current trials compare various policies, including time-based or physiology-based deferred cord clamping, and cord milking. Individual participant data (IPD) enable exploration of different strategies within subgroups. Network meta-analysis (NMA) enables comparison and ranking of all available interventions using a combination of direct and indirect comparisons. Objectives: (1) To evaluate the effectiveness of cord management strategies for preterm infants on neonatal mortality and morbidity overall and for different participant characteristics using IPD meta-analysis. (2) To evaluate and rank the effect of different cord management strategies for preterm births on mortality and other key outcomes using NMA. Methods and analysis: Systematic searches of Medline, Embase, clinical trial registries, and other sources for all ongoing and completed randomised controlled trials comparing cord management strategies at preterm birth (before 37 weeks' gestation) have been completed up to 13 February 2019, but will be updated regularly to include additional trials. IPD will be sought for all trials; aggregate summary data will be included where IPD are unavailable. First, deferred clamping and cord milking will be compared with immediate clamping in pairwise IPD meta-analyses. The primary outcome will be death prior to hospital discharge. Effect differences will be explored for prespecified participant subgroups. Second, all identified cord management strategies will be compared and ranked in an IPD NMA for the primary outcome and the key secondary outcomes. Treatment effect differences by participant characteristics will be identified. Inconsistency and heterogeneity will be explored. Ethics and dissemination: Ethics approval for this project has been granted by the University of Sydney Human Research Ethics Committee (2018/886). Results will be relevant to clinicians, guideline developers and policy-makers, and will be disseminated via publications, presentations and media releases. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskapx Hälso- och sjukvårdsorganisation, hälsopolitik och hälsoekonomi0 (SwePub)303012 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Health Sciencesx Health Care Service and Management, Health Policy and Services and Health Economy0 (SwePub)303012 hsv//eng |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Pediatrik0 (SwePub)302212 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Pediatrics0 (SwePub)302212 hsv//eng |
653 | a individual participant data meta-analysis | |
653 | a network meta-analysis | |
653 | a placental transfusion | |
653 | a preterm birth | |
653 | a prospective meta-analysis | |
653 | a umbilical cord clamping | |
653 | a umbilical cord milking | |
700 | 1 | a Duley, Leliau University of Nottingham4 aut |
700 | 1 | a Katheria, Anup C.u Sharp Mary Birch Hospital for Women & Newborns, Sharp HealthCare4 aut |
700 | 1 | a De Paco Matallana, Catalinau Hospital Virgen de la Arrixaca4 aut |
700 | 1 | a Dempsey, Eugeneu Cork University Hospital4 aut |
700 | 1 | a Rabe, Heikeu Brighton and Sussex University Hospitals NHS Trust4 aut |
700 | 1 | a Kattwinkel, Johnu University of Virginia4 aut |
700 | 1 | a Mercer, Judithu University of Rhode Island4 aut |
700 | 1 | a Josephsen, Justinu Saint Louis University School of Medicine4 aut |
700 | 1 | a Fairchild, Karenu University of Virginia4 aut |
700 | 1 | a Andersson, Olau Lund University,Lunds universitet,Neonatologi,Forskargrupper vid Lunds universitet,Neonatology,Lund University Research Groups,Skåne University Hospital4 aut0 (Swepub:lu)ol5716an |
700 | 1 | a Hosono, Shigeharuu Jichi Medical University4 aut |
700 | 1 | a Sundaram, Venkataseshanu Postgraduate Institute of Medical Education and Research4 aut |
700 | 1 | a Datta, Vikramu University of Delhi4 aut |
700 | 1 | a El-Naggar, Walidu Dalhousie University4 aut |
700 | 1 | a Tarnow-Mordi, Williamu University of Sydney4 aut |
700 | 1 | a Debray, Thomasu University Medical Center Utrecht4 aut |
700 | 1 | a Hooper, Stuart B.u Monash University4 aut |
700 | 1 | a Kluckow, Martinu University of Sydney4 aut |
700 | 1 | a Polglase, Graemeu Monash University4 aut |
700 | 1 | a Davis, Peter G.u The Royal Women's Hospital4 aut |
700 | 1 | a Montgomery, Alanu University of Nottingham4 aut |
700 | 1 | a Hunter, Kylie E.u University of Sydney4 aut |
700 | 1 | a Barba, Angieu University of Sydney4 aut |
700 | 1 | a Simes, Johnu University of Sydney4 aut |
700 | 1 | a Askie, Lisau University of Sydney4 aut |
710 | 2 | a University of Sydneyb University of Nottingham4 org |
773 | 0 | t BMJ Opend : BMJg 10:3q 10:3x 2044-6055 |
856 | 4 | u http://dx.doi.org/10.1136/bmjopen-2019-034595x freey FULLTEXT |
856 | 4 | u https://bmjopen.bmj.com/content/bmjopen/10/3/e034595.full.pdf |
856 | 4 8 | u https://lup.lub.lu.se/record/d41d6a33-bf6b-444f-a255-16b63cef2227 |
856 | 4 8 | u https://doi.org/10.1136/bmjopen-2019-034595 |
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