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WFRF:(Sundaram Venkataseshan)
 

Sökning: WFRF:(Sundaram Venkataseshan) > Systematic review a...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00006023naa a2200709 4500
001oai:lup.lub.lu.se:d41d6a33-bf6b-444f-a255-16b63cef2227
003SwePub
008200420s2020 | |||||||||||000 ||eng|
024a https://lup.lub.lu.se/record/d41d6a33-bf6b-444f-a255-16b63cef22272 URI
024a https://doi.org/10.1136/bmjopen-2019-0345952 DOI
040 a (SwePub)lu
041 a engb eng
042 9 SwePub
072 7a for2 swepub-publicationtype
072 7a ref2 swepub-contenttype
100a Seidler, Anna Leneu University of Sydney4 aut
2451 0a Systematic review and network meta-analysis with individual participant data on cord management at preterm birth (iCOMP) : Study protocol
264 c 2020-03-29
264 1b BMJ,c 2020
520 a Introduction: Timing of cord clamping and other cord management strategies may improve outcomes at preterm birth. However, it is unclear whether benefits apply to all preterm subgroups. Previous and current trials compare various policies, including time-based or physiology-based deferred cord clamping, and cord milking. Individual participant data (IPD) enable exploration of different strategies within subgroups. Network meta-analysis (NMA) enables comparison and ranking of all available interventions using a combination of direct and indirect comparisons. Objectives: (1) To evaluate the effectiveness of cord management strategies for preterm infants on neonatal mortality and morbidity overall and for different participant characteristics using IPD meta-analysis. (2) To evaluate and rank the effect of different cord management strategies for preterm births on mortality and other key outcomes using NMA. Methods and analysis: Systematic searches of Medline, Embase, clinical trial registries, and other sources for all ongoing and completed randomised controlled trials comparing cord management strategies at preterm birth (before 37 weeks' gestation) have been completed up to 13 February 2019, but will be updated regularly to include additional trials. IPD will be sought for all trials; aggregate summary data will be included where IPD are unavailable. First, deferred clamping and cord milking will be compared with immediate clamping in pairwise IPD meta-analyses. The primary outcome will be death prior to hospital discharge. Effect differences will be explored for prespecified participant subgroups. Second, all identified cord management strategies will be compared and ranked in an IPD NMA for the primary outcome and the key secondary outcomes. Treatment effect differences by participant characteristics will be identified. Inconsistency and heterogeneity will be explored. Ethics and dissemination: Ethics approval for this project has been granted by the University of Sydney Human Research Ethics Committee (2018/886). Results will be relevant to clinicians, guideline developers and policy-makers, and will be disseminated via publications, presentations and media releases.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskapx Hälso- och sjukvårdsorganisation, hälsopolitik och hälsoekonomi0 (SwePub)303012 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Health Sciencesx Health Care Service and Management, Health Policy and Services and Health Economy0 (SwePub)303012 hsv//eng
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Pediatrik0 (SwePub)302212 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Pediatrics0 (SwePub)302212 hsv//eng
653 a individual participant data meta-analysis
653 a network meta-analysis
653 a placental transfusion
653 a preterm birth
653 a prospective meta-analysis
653 a umbilical cord clamping
653 a umbilical cord milking
700a Duley, Leliau University of Nottingham4 aut
700a Katheria, Anup C.u Sharp Mary Birch Hospital for Women & Newborns, Sharp HealthCare4 aut
700a De Paco Matallana, Catalinau Hospital Virgen de la Arrixaca4 aut
700a Dempsey, Eugeneu Cork University Hospital4 aut
700a Rabe, Heikeu Brighton and Sussex University Hospitals NHS Trust4 aut
700a Kattwinkel, Johnu University of Virginia4 aut
700a Mercer, Judithu University of Rhode Island4 aut
700a Josephsen, Justinu Saint Louis University School of Medicine4 aut
700a Fairchild, Karenu University of Virginia4 aut
700a Andersson, Olau Lund University,Lunds universitet,Neonatologi,Forskargrupper vid Lunds universitet,Neonatology,Lund University Research Groups,Skåne University Hospital4 aut0 (Swepub:lu)ol5716an
700a Hosono, Shigeharuu Jichi Medical University4 aut
700a Sundaram, Venkataseshanu Postgraduate Institute of Medical Education and Research4 aut
700a Datta, Vikramu University of Delhi4 aut
700a El-Naggar, Walidu Dalhousie University4 aut
700a Tarnow-Mordi, Williamu University of Sydney4 aut
700a Debray, Thomasu University Medical Center Utrecht4 aut
700a Hooper, Stuart B.u Monash University4 aut
700a Kluckow, Martinu University of Sydney4 aut
700a Polglase, Graemeu Monash University4 aut
700a Davis, Peter G.u The Royal Women's Hospital4 aut
700a Montgomery, Alanu University of Nottingham4 aut
700a Hunter, Kylie E.u University of Sydney4 aut
700a Barba, Angieu University of Sydney4 aut
700a Simes, Johnu University of Sydney4 aut
700a Askie, Lisau University of Sydney4 aut
710a University of Sydneyb University of Nottingham4 org
773t BMJ Opend : BMJg 10:3q 10:3x 2044-6055
856u http://dx.doi.org/10.1136/bmjopen-2019-034595x freey FULLTEXT
856u https://bmjopen.bmj.com/content/bmjopen/10/3/e034595.full.pdf
8564 8u https://lup.lub.lu.se/record/d41d6a33-bf6b-444f-a255-16b63cef2227
8564 8u https://doi.org/10.1136/bmjopen-2019-034595

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