WFRF:(Thunberg Ulrica 1967 )
Sökning: WFRF:(Thunberg Ulrica 1967 ) > Ototoxicity associa...
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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 02999naa a2200349 4500 | |
| 001 | oai:DiVA.org:oru-109339 | |
| 003 | SwePub | |
| 008 | 231020s2023 | |||||||||||000 ||eng| | |
| 024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-1093392 URI |
| 024 | 7 | a https://doi.org/10.1186/s12879-023-08709-82 DOI |
| 040 | a (SwePub)oru | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a art2 swepub-publicationtype |
| 100 | 1 | a Lange, Anna,d 1975-u Örebro universitet,Institutionen för medicinska vetenskaper,Region Örebro län,Department of Infectious Diseases4 aut0 (Swepub:oru)aalg |
| 245 | 1 0 | a Ototoxicity associated with extended dalbavancin treatment for a shoulder prosthetic joint infection |
| 264 | 1 | b BioMed Central (BMC),c 2023 |
| 338 | a print2 rdacarrier | |
| 520 | a BACKGROUND: Dalbavancin is a lipoglycopeptide antibiotic approved for treatment of skin and soft tissue infections, administered as a single or two-dose treatment. The extended half-life, good penetration into bone and synovial fluid, and bactericidal activity against gram-positive bacteria, including those in biofilm, make dalbavancin an appealing choice for treatment of bone and joint infections in outpatient settings. However, we present a rare case of ototoxicity associated with off-label extended dalbavancin treatment of a prosthetic joint infection.CASE PRESENTATION: A 55-year-old man with a prosthetic joint infection of the shoulder underwent off-label extended dalbavancin treatment, receiving a cumulative dose of 2500 mg. The patient experienced a gradual onset of hearing loss following the first dose, leading to a diagnosis of bilateral sensorineural hearing loss that persisted 1 year after dalbavancin was discontinued.CONCLUSIONS: This case report highlights the importance of exercising caution when administering dalbavancin beyond approved dosing guidelines, and emphasizes the need for vigilance regarding the potential for ototoxicity. | |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Infektionsmedicin0 (SwePub)302092 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Infectious Medicine0 (SwePub)302092 hsv//eng |
| 653 | a Dalbavancin | |
| 653 | a Ototoxicity | |
| 653 | a Prosthetic joint infection | |
| 700 | 1 | a Thunberg, Ulrica,d 1967-u Örebro universitet,Institutionen för hälsovetenskaper,Institutionen för medicinska vetenskaper,Department of Otorhinolaryngology4 aut0 (Swepub:oru)uatg |
| 700 | 1 | a Söderquist, Bo,d 1955-u Örebro universitet,Institutionen för medicinska vetenskaper4 aut0 (Swepub:oru)bost |
| 710 | 2 | a Örebro universitetb Institutionen för medicinska vetenskaper4 org |
| 773 | 0 | t BMC Infectious Diseasesd : BioMed Central (BMC)g 23:1q 23:1x 1471-2334 |
| 856 | 4 | u https://doi.org/10.1186/s12879-023-08709-8y Fulltext |
| 856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-109339 |
| 856 | 4 8 | u https://doi.org/10.1186/s12879-023-08709-8 |
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