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Release of Satiety ...
Release of Satiety Hormones in Response to Specific Dietary Proteins Is Different between Human and Murine Small Intestinal Mucosa
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- Geraedts, Maartje C. P. (författare)
- Med Ctr, Dept Human Biol, Maastricht Univ, Maastricht, Netherlands,Maastricht University
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- Troost, Freddy J. (författare)
- Med Ctr, Dept Internal Med, Div Gastroenterol & Hepatol, Maastricht Univ, Maastricht, Netherlands,Maastricht University
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- Tinnemans, Rik (författare)
- Med Ctr, Dept Anim Res & Testing Serv, Maastricht Univ, Maastricht, Netherlands,Maastricht University
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- Söderholm, Johan D (författare)
- Östergötlands Läns Landsting,Linköpings universitet,Kirurgi,Hälsouniversitetet,Kirurgiska kliniken i Östergötland med verksamhet i Linköping, Norrköping och Motala
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- Brummer, Robert (författare)
- Örebro universitet,Hälsoakademin,Med Ctr, Dept Internal Med, Div Gastroenterol & Hepatol, Maastricht Univ, Maastricht, Netherlands,Maastricht University
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- Saris, Wim H. M. (författare)
- Med Ctr, Dept Human Biol, Maastricht Univ, Maastricht, Netherlands,Maastricht University
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(creator_code:org_t)
- 2010-06-08
- 2010
- Engelska.
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Ingår i: Annals of Nutrition and Metabolism. - : S. Karger AG. - 0250-6807 .- 1421-9697. ; 56:4, s. 308-313
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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Abstract
Ämnesord
Stäng
- Background/Aim: High protein diets are the most effective to stimulate cholecystokinin (CCK) and glucagon-like peptide 1 (GLP-1) release; however, which proteins are the most potent is not known. Here, the effects of specific dietary proteins on intestinal CCK and GLP-1 release were examined. Methods: Duodenal biopsies of 10 healthy male subjects and 10 male rats were taken and placed in an Ussing chamber system. The biopsies were exposed on the luminal side to buffer, egg protein, codfish protein, ovomucoid, pea protein, and wheat protein. After an exposure time of 2 h, samples were taken from the serosal side. Results: Pea protein and wheat protein increased CCK and GLP-1 release in human duodenal tissue, while codfish protein only increased CCK release. No elevated levels of CCK and GLP-1 were found after exposure of rat tissue to different proteins. Conclusion: Pea and wheat protein are the most potent stimulators of CCK and GLP-1 release in human duodenal tissue, and may therefore be good dietary additives in weight management. Copyright (C) 2010 S. Karger AG, Basel
Nyckelord
- Dietary protein
- Duodenal tissue
- human
- Duodenal tissue
- rat
- Satiety hormone
- MEDICINE
- MEDICIN
- Medicine
- Medicin
Publikations- och innehållstyp
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- art (ämneskategori)
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