Sökning: WFRF:(Wielgosz Andreas) > (2023) > Associations of Ant...
Fältnamn | Indikatorer | Metadata |
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000 | 05598naa a2201021 4500 | |
001 | oai:gup.ub.gu.se/328863 | |
003 | SwePub | |
008 | 240910s2023 | |||||||||||000 ||eng| | |
009 | oai:prod.swepub.kib.ki.se:153741466 | |
024 | 7 | a https://gup.ub.gu.se/publication/3288632 URI |
024 | 7 | a https://doi.org/10.1016/j.cgh.2022.11.0372 DOI |
024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1537414662 URI |
040 | a (SwePub)gud (SwePub)ki | |
041 | a eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Narula, Neeraj4 aut |
245 | 1 0 | a Associations of Antibiotics, Hormonal Therapies, Oral Contraceptives, and Long-Term NSAIDS With Inflammatory Bowel Disease: Results From the Prospective Urban Rural Epidemiology (PURE) Study. |
264 | 1 | b Elsevier BV,c 2023 |
520 | a Several medications have been suspected to contribute to the etiology of inflammatory bowel disease (IBD). This study assessed the association between medication use and the risk of developing IBD using the Prospective Urban Rural Epidemiology cohort.This was a prospective cohort study of 133,137 individuals between the ages of 20 and 80 from 24 countries. Country-specific validated questionnaires documented baseline and follow-up medication use. Participants were followed up prospectively at least every 3 years. The main outcome was the development of IBD, including Crohn's disease (CD) and ulcerative colitis (UC). Short-term (baseline but not follow-up use) and long-term use (baseline and subsequent follow-up use) were evaluated. Results are presented as adjusted odds ratios (aORs) with 95% CIs.During a median follow-up period of 11.0 years (interquartile range, 9.2-12.2 y), there were 571 incident IBD cases (143 CD and 428 UC). Incident IBD was associated significantly with baseline antibiotic (aOR, 2.81; 95% CI, 1.67-4.73; P= .0001) and hormonal medication use (aOR, 4.43; 95% CI, 1.78-11.01; P= .001). Among females, previous or current oral contraceptive use also was associated with IBD development (aOR, 2.17; 95% CI, 1.70-2.77; P < .001). Nonsteroidal anti-inflammatory drug users also were observed to have increased odds of IBD (aOR, 1.80; 95% CI, 1.23-2.64; P= .002), which was driven by long-term use (aOR, 5.58; 95% CI, 2.26-13.80; P < .001). All significant results were consistent in direction for CD and UC with low heterogeneity.Antibiotics, hormonal medications, oral contraceptives, and long-term nonsteroidal anti-inflammatory drug use were associated with increased odds of incident IBD after adjustment for covariates. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicin0 (SwePub)3022 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicine0 (SwePub)3022 hsv//eng |
653 | a Female | |
653 | a Humans | |
653 | a Young Adult | |
653 | a Adult | |
653 | a Middle Aged | |
653 | a Aged | |
653 | a Aged | |
653 | a 80 and over | |
653 | a Contraceptives | |
653 | a Oral | |
653 | a Prospective Studies | |
653 | a Anti-Inflammatory Agents | |
653 | a Non-Steroidal | |
653 | a adverse effects | |
653 | a Anti-Bacterial Agents | |
653 | a adverse effects | |
653 | a Risk Factors | |
653 | a Inflammatory Bowel Diseases | |
653 | a drug therapy | |
653 | a epidemiology | |
653 | a Colitis | |
653 | a Ulcerative | |
653 | a drug therapy | |
653 | a Crohn Disease | |
653 | a drug therapy | |
653 | a Surveys and Questionnaires | |
700 | 1 | a Wong, Emily C L4 aut |
700 | 1 | a Pray, Cara4 aut |
700 | 1 | a Marshall, John K4 aut |
700 | 1 | a Rangarajan, Sumathy4 aut |
700 | 1 | a Islam, Shofiqul4 aut |
700 | 1 | a Bahonar, Ahmad4 aut |
700 | 1 | a Alhabib, Khalid F4 aut |
700 | 1 | a Kontsevaya, Anna4 aut |
700 | 1 | a Ariffin, Farnaza4 aut |
700 | 1 | a Co, Homer U4 aut |
700 | 1 | a Al Sharief, Wadeia4 aut |
700 | 1 | a Szuba, Andrzej4 aut |
700 | 1 | a Wielgosz, Andreas4 aut |
700 | 1 | a Diaz, Maria Luz4 aut |
700 | 1 | a Yusuf, Rita4 aut |
700 | 1 | a Kruger, Lanthé4 aut |
700 | 1 | a Soman, Biju4 aut |
700 | 1 | a Li, Yang4 aut |
700 | 1 | a Wang, Chuangshi4 aut |
700 | 1 | a Yin, Luu Karolinska Institutet4 aut |
700 | 1 | a Mirrakhimov, Erkin4 aut |
700 | 1 | a Lanas, Fernando4 aut |
700 | 1 | a Davletov, Kairat4 aut |
700 | 1 | a Rosengren, Annika,d 1951u Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine4 aut0 (Swepub:gu)xrosan |
700 | 1 | a Lopez-Jaramillo, Patricio4 aut |
700 | 1 | a Khatib, Rasha4 aut |
700 | 1 | a Oguz, Aytekin4 aut |
700 | 1 | a Iqbal, Romaina4 aut |
700 | 1 | a Yeates, Karen4 aut |
700 | 1 | a Avezum, Álvaro4 aut |
700 | 1 | a Reinisch, Walter4 aut |
700 | 1 | a Moayyedi, Paul4 aut |
700 | 1 | a Yusuf, Salim4 aut |
710 | 2 | a Karolinska Institutetb Institutionen för medicin, avdelningen för molekylär och klinisk medicin4 org |
773 | 0 | t Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Associationd : Elsevier BVg 21:10q 21:10x 1542-7714 |
773 | 0 | t Clinical Gastroenterology and Hepatologyd : Elsevier BVg 21:10q 21:10x 1542-3565 |
856 | 4 8 | u https://gup.ub.gu.se/publication/328863 |
856 | 4 8 | u https://doi.org/10.1016/j.cgh.2022.11.037 |
856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:153741466 |
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