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Sökning: WFRF:(Wielgosz Andreas) > (2023) > Associations of Ant...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00005598naa a2201021 4500
001oai:gup.ub.gu.se/328863
003SwePub
008240910s2023 | |||||||||||000 ||eng|
009oai:prod.swepub.kib.ki.se:153741466
024a https://gup.ub.gu.se/publication/3288632 URI
024a https://doi.org/10.1016/j.cgh.2022.11.0372 DOI
024a http://kipublications.ki.se/Default.aspx?queryparsed=id:1537414662 URI
040 a (SwePub)gud (SwePub)ki
041 a eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
100a Narula, Neeraj4 aut
2451 0a Associations of Antibiotics, Hormonal Therapies, Oral Contraceptives, and Long-Term NSAIDS With Inflammatory Bowel Disease: Results From the Prospective Urban Rural Epidemiology (PURE) Study.
264 1b Elsevier BV,c 2023
520 a Several medications have been suspected to contribute to the etiology of inflammatory bowel disease (IBD). This study assessed the association between medication use and the risk of developing IBD using the Prospective Urban Rural Epidemiology cohort.This was a prospective cohort study of 133,137 individuals between the ages of 20 and 80 from 24 countries. Country-specific validated questionnaires documented baseline and follow-up medication use. Participants were followed up prospectively at least every 3 years. The main outcome was the development of IBD, including Crohn's disease (CD) and ulcerative colitis (UC). Short-term (baseline but not follow-up use) and long-term use (baseline and subsequent follow-up use) were evaluated. Results are presented as adjusted odds ratios (aORs) with 95% CIs.During a median follow-up period of 11.0 years (interquartile range, 9.2-12.2 y), there were 571 incident IBD cases (143 CD and 428 UC). Incident IBD was associated significantly with baseline antibiotic (aOR, 2.81; 95% CI, 1.67-4.73; P= .0001) and hormonal medication use (aOR, 4.43; 95% CI, 1.78-11.01; P= .001). Among females, previous or current oral contraceptive use also was associated with IBD development (aOR, 2.17; 95% CI, 1.70-2.77; P < .001). Nonsteroidal anti-inflammatory drug users also were observed to have increased odds of IBD (aOR, 1.80; 95% CI, 1.23-2.64; P= .002), which was driven by long-term use (aOR, 5.58; 95% CI, 2.26-13.80; P < .001). All significant results were consistent in direction for CD and UC with low heterogeneity.Antibiotics, hormonal medications, oral contraceptives, and long-term nonsteroidal anti-inflammatory drug use were associated with increased odds of incident IBD after adjustment for covariates.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicin0 (SwePub)3022 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicine0 (SwePub)3022 hsv//eng
653 a Female
653 a Humans
653 a Young Adult
653 a Adult
653 a Middle Aged
653 a Aged
653 a Aged
653 a 80 and over
653 a Contraceptives
653 a Oral
653 a Prospective Studies
653 a Anti-Inflammatory Agents
653 a Non-Steroidal
653 a adverse effects
653 a Anti-Bacterial Agents
653 a adverse effects
653 a Risk Factors
653 a Inflammatory Bowel Diseases
653 a drug therapy
653 a epidemiology
653 a Colitis
653 a Ulcerative
653 a drug therapy
653 a Crohn Disease
653 a drug therapy
653 a Surveys and Questionnaires
700a Wong, Emily C L4 aut
700a Pray, Cara4 aut
700a Marshall, John K4 aut
700a Rangarajan, Sumathy4 aut
700a Islam, Shofiqul4 aut
700a Bahonar, Ahmad4 aut
700a Alhabib, Khalid F4 aut
700a Kontsevaya, Anna4 aut
700a Ariffin, Farnaza4 aut
700a Co, Homer U4 aut
700a Al Sharief, Wadeia4 aut
700a Szuba, Andrzej4 aut
700a Wielgosz, Andreas4 aut
700a Diaz, Maria Luz4 aut
700a Yusuf, Rita4 aut
700a Kruger, Lanthé4 aut
700a Soman, Biju4 aut
700a Li, Yang4 aut
700a Wang, Chuangshi4 aut
700a Yin, Luu Karolinska Institutet4 aut
700a Mirrakhimov, Erkin4 aut
700a Lanas, Fernando4 aut
700a Davletov, Kairat4 aut
700a Rosengren, Annika,d 1951u Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine4 aut0 (Swepub:gu)xrosan
700a Lopez-Jaramillo, Patricio4 aut
700a Khatib, Rasha4 aut
700a Oguz, Aytekin4 aut
700a Iqbal, Romaina4 aut
700a Yeates, Karen4 aut
700a Avezum, Álvaro4 aut
700a Reinisch, Walter4 aut
700a Moayyedi, Paul4 aut
700a Yusuf, Salim4 aut
710a Karolinska Institutetb Institutionen för medicin, avdelningen för molekylär och klinisk medicin4 org
773t Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Associationd : Elsevier BVg 21:10q 21:10x 1542-7714
773t Clinical Gastroenterology and Hepatologyd : Elsevier BVg 21:10q 21:10x 1542-3565
8564 8u https://gup.ub.gu.se/publication/328863
8564 8u https://doi.org/10.1016/j.cgh.2022.11.037
8564 8u http://kipublications.ki.se/Default.aspx?queryparsed=id:153741466

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