WFRF:(van Acker K.)
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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 04276naa a2200541 4500 | |
| 001 | oai:lup.lub.lu.se:f235b150-09b9-449d-8819-4daebcc24f9f | |
| 003 | SwePub | |
| 008 | 170120s2017 | |||||||||||000 ||eng| | |
| 024 | 7 | a https://lup.lub.lu.se/record/f235b150-09b9-449d-8819-4daebcc24f9f2 URI |
| 024 | 7 | a https://doi.org/10.1002/dmrr.28672 DOI |
| 040 | a (SwePub)lu | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a art2 swepub-publicationtype |
| 072 | 7 | a ref2 swepub-contenttype |
| 100 | 1 | a Pickwell, K.u Maastricht University4 aut |
| 245 | 1 0 | a Minor amputation does not negatively affect health-related quality of life as compared with conservative treatment in patients with a diabetic foot ulcer : An observational study |
| 264 | c 2016-11-30 | |
| 264 | 1 | b Wiley,c 2017 |
| 520 | a Background: Health-related quality of life (HRQoL) is poor in patients with persistent diabetic foot ulcers and poor HRQoL predicts worse outcomes in these patients. Amputation is often considered a treatment failure, which is why conservative treatment is generally preferred over amputation. However, it is unclear whether minor amputation negatively affects HRQoL compared with conservative treatment in patients with diabetic foot ulcers. Methods: In the cohort of the multicenter, prospective, observational Eurodiale study, we determined difference in change of HRQoL measured by EQ-5D between patients with a diabetic foot ulcers that healed after conservative treatment (n = 676) and after minor amputation (n = 145). Propensity score was used to adjust for known confounders, attempting to overcome lack of randomization. Results: Baseline HRQoL was not significantly different between patients treated conservatively and undergoing minor amputation. In addition, there was no difference in the change of HRQoL between these groups. In patients who healed 6 to 12 months after the first visit, HRQoL on the anxiety/depression subscale even appeared to improve more in those who underwent minor amputation. Conclusions: Minor amputation was not associated with a negative impact on HRQoL in patients with a diabetic foot ulcers. It may therefore not be considered treatment failure in terms of HRQoL but rather a viable treatment option. A randomized controlled trial is warranted to further examine the influence of minor amputations on health-related quality of life. | |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Endokrinologi och diabetes0 (SwePub)302052 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Endocrinology and Diabetes0 (SwePub)302052 hsv//eng |
| 653 | a Diabetic foot ulcer | |
| 653 | a Euroqol 5D | |
| 653 | a Health-related quality of life | |
| 653 | a Minor amputation | |
| 700 | 1 | a Siersma, V.u University of Copenhagen4 aut |
| 700 | 1 | a Kars, M.u Maastricht University4 aut |
| 700 | 1 | a Apelqvist, J.u Lund University,Lunds universitet,Translationell muskelforskning,Forskargrupper vid Lunds universitet,Translational Muscle Research,Lund University Research Groups4 aut0 (Swepub:lu)endo-jap |
| 700 | 1 | a Bakker, K.u International Working Group on the Diabetic Foot4 aut |
| 700 | 1 | a Edmonds, M.u King's College Hospital4 aut |
| 700 | 1 | a Holstein, P.u Bispebjerg Hospital4 aut |
| 700 | 1 | a Jirkovská, A.u Institute for Clinical and Experimental Medicine (IKEM)4 aut |
| 700 | 1 | a Jude, E. B.4 aut |
| 700 | 1 | a Mauricio, D.u Autonomous University of Barcelona4 aut |
| 700 | 1 | a Piaggesi, A.u University Hospital of Pisa4 aut |
| 700 | 1 | a Reike, H.u Mariannen-Hospital Werl4 aut |
| 700 | 1 | a Spraul, M.u Klinikum Rheine4 aut |
| 700 | 1 | a Uccioli, L.u University of Rome Tor Vergata4 aut |
| 700 | 1 | a Urbancic, V.u University Medical Centre Ljubljana4 aut |
| 700 | 1 | a van Acker, K.u Centre de Santé des Fagnes4 aut |
| 700 | 1 | a van Baal, J.4 aut |
| 700 | 1 | a Schaper, N.u Maastricht University4 aut |
| 710 | 2 | a Maastricht Universityb University of Copenhagen4 org |
| 773 | 0 | t Diabetes/Metabolism Research and Reviewsd : Wileyg 33:3q 33:3x 1520-7552 |
| 856 | 4 | u http://dx.doi.org/10.1002/dmrr.2867y FULLTEXT |
| 856 | 4 8 | u https://lup.lub.lu.se/record/f235b150-09b9-449d-8819-4daebcc24f9f |
| 856 | 4 8 | u https://doi.org/10.1002/dmrr.2867 |
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- Pickwell, K.
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- Holstein, P.
- Jirkovská, A.
- Jude, E. B.
- Mauricio, D.
- Piaggesi, A.
- Reike, H.
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- Uccioli, L.
- Urbancic, V.
- van Acker, K.
- van Baal, J.
- Schaper, N.
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