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Sökning: onr:"swepub:oai:DiVA.org:su-184340" > Late-life depressio...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00003734naa a2200457 4500
001oai:DiVA.org:su-184340
003SwePub
008200930s2020 | |||||||||||000 ||eng|
024a https://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-1843402 URI
024a https://doi.org/10.1016/j.jad.2020.05.0592 DOI
040 a (SwePub)su
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
100a Wu, Jia-Jia4 aut
2451 0a Late-life depression and the risk of dementia in 14 countries :b a 10-year follow-up study from the Survey of Health, Ageing and Retirement in Europe
264 1b Elsevier BV,c 2020
338 a print2 rdacarrier
520 a Background: Depression is the most common mental health problem and often co-occurs with dementia in old age. This study investigates the in fluence of late-life depression on risk of dementia.Methods: A total of 16210 dementia-free participants aged 60+ from the Survey of Health, Aging, and Retirement in Europe were followed up for 10 years to detect incident dementia. Depression was assessed by a 12-item Europe-depression scale, dementia was determined by physician diagnosis reported by the participants and their informants. Fine and Gray model was performed to explore the association between depression and incident dementia taking into account competing risk of death.Results: During an average of 8 years follow-up, 1030 (6.35%) incident dementia were identi fied. Late-life depression was related to higher subdistribution hazard ratio (sHR) of dementia (sHR=1.52, 95%CI: 1.32-1.75) after adjusting for age, gender, country, education, smoking, drinking, living arrangement, BMI, chronic disease, and physical activity. Further, the risk was only existed in those below age of 80 (sHR=1.75, 95%CI: 1.47-2.07). In addition, a dose-response association was observed between the severity of depression and dementia risk (p for trend<0.001).Limitation: The ascertainment of depression and dementia was based on information reported by the participants and/or their informants, which might result in information bias. The causal relationship could not be determined because limited follow-up time.Conclusions: Late-life depression is associated with higher incidence of dementia in a dose-response fashion. Interventions targeting depression patients aged 60-79 years and those with severe depression may be e ffective strategies to prevent dementia.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Geriatrik0 (SwePub)302222 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Geriatrics0 (SwePub)302222 hsv//eng
650 7a SAMHÄLLSVETENSKAPx Psykologi0 (SwePub)5012 hsv//swe
650 7a SOCIAL SCIENCESx Psychology0 (SwePub)5012 hsv//eng
653 a depression
653 a dementia
653 a Europe
653 a late-life
653 a dose-response
653 a Psychology
653 a psykologi
700a Wang, Hui-Xinu Stockholms universitet,Stressforskningsinstitutet,Zhengzhou University, China4 aut0 (Swepub:su)huiwa
700a Yao, Wu4 aut
700a Yan, Zhen4 aut
700a Pei, Jin-Jingu Stockholms universitet,Stressforskningsinstitutet4 aut0 (Swepub:su)jipe9374
710a Stockholms universitetb Stressforskningsinstitutet4 org
773t Journal of Affective Disordersd : Elsevier BVg 274, s. 671-677q 274<671-677x 0165-0327x 1573-2517
856u https://doi.org/10.1016/j.jad.2020.05.059y Fulltext
856u https://doi.org/10.1016/j.jad.2020.05.059
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-184340
8564 8u https://doi.org/10.1016/j.jad.2020.05.059

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Wu, Jia-Jia
Wang, Hui-Xin
Yao, Wu
Yan, Zhen
Pei, Jin-Jing
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MEDICIN OCH HÄLSOVETENSKAP
MEDICIN OCH HÄLS ...
och Klinisk medicin
och Geriatrik
SAMHÄLLSVETENSKAP
SAMHÄLLSVETENSKA ...
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Stockholms universitet

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