onr:"swepub:oai:DiVA.org:umu-42831"
Sökning: onr:"swepub:oai:DiVA.org:umu-42831" > The role of placent...
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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 02469naa a2200301 4500 | |
| 001 | oai:DiVA.org:umu-42831 | |
| 003 | SwePub | |
| 008 | 110413s2010 | |||||||||||000 ||eng| | |
| 024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-428312 URI |
| 024 | 7 | a https://doi.org/10.1111/j.1600-0897.2010.00822.x2 DOI |
| 040 | a (SwePub)umu | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a art2 swepub-publicationtype |
| 100 | 1 | a Mincheva-Nilsson, Lucia,d 1951-u Umeå universitet,Klinisk immunologi4 aut0 (Swepub:umu)lumi0001 |
| 245 | 1 0 | a The role of placental exosomes in reproduction |
| 264 | c 2010-03-11 | |
| 264 | 1 | b Wiley,c 2010 |
| 338 | a print2 rdacarrier | |
| 520 | a Cell communication comprises cell-cell contact, soluble mediators and intercellular nanotubes. There is, however, another cell-cell communication by released membrane-bound microvesicles that convey cell-cell contact 'by proxy' transporting signals/packages of information from donor to recipient cells locally and/or at a distance. The nanosized exosomes comprise a specialized type of microvesicles generated within multivesicular bodies (MVB) and released upon MVB fusion with the plasma membrane. Exosomes are produced by a variety of immune, epithelial and tumor cells. Upon contact, exosomes transfer molecules that can render new properties and/or reprogram their recipient cells. Recently, it was discovered that the syncytiotrophoblast constitutively and throughout the pregnancy secretes exosomes. The placenta-derived exosomes are immunosuppressive and carry proteins and RNA molecules that in a redundant way influence a number of mechanisms and promote the fetal allograft survival. In this review, we summarize the current knowledge on the nature of placenta-derived exosomes and discuss their role in pregnancy. | |
| 653 | a Exosomes; FasL; MICA/B; microvesicles; placenta; ULBP | |
| 700 | 1 | a Baranov, Vladimir,d 1940-u Umeå universitet,Klinisk immunologi4 aut0 (Swepub:umu)vlba0001 |
| 710 | 2 | a Umeå universitetb Klinisk immunologi4 org |
| 773 | 0 | t American Journal of Reproductive Immunology and Microbiologyd : Wileyg 63:6, s. 520-533q 63:6<520-533x 8755-8920x 1046-7408x 1600-0897 |
| 856 | 4 | u https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1600-0897.2010.00822.x |
| 856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-42831 |
| 856 | 4 8 | u https://doi.org/10.1111/j.1600-0897.2010.00822.x |
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