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Sökning: onr:"swepub:oai:DiVA.org:uu-409789" > Amount and Intensit...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00006525naa a2200565 4500
001oai:DiVA.org:uu-409789
003SwePub
008200504s2020 | |||||||||||000 ||eng|
009oai:prod.swepub.kib.ki.se:143285709
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-4097892 URI
0247 a https://doi.org/10.1200/JCO.19.024072 DOI
0247 a http://kipublications.ki.se/Default.aspx?queryparsed=id:1432857092 URI
040 a (SwePub)uud (SwePub)ki
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Matthews, Charles E.u NCI, Div Canc Epidemiol & Genet, Metab Epidemiol Branch, Bethesda, MD 20892 USA4 aut
2451 0a Amount and Intensity of Leisure-Time Physical Activity and Lower Cancer Risk
264 1b AMER SOC CLINICAL ONCOLOGY,c 2020
338 a electronic2 rdacarrier
520 a PURPOSE: To determine whether recommended amounts of leisure-time physical activity (ie, 7.5-15 metabolic equivalent task [MET] hours/week) are associated with lower cancer risk, describe the shape of the dose-response relationship, and explore associations with moderate- and vigorous-intensity physical activity.METHODS: Data from 9 prospective cohorts with self-reported leisure-time physical activity and follow-up for cancer incidence were pooled. Multivariable Cox regression was used to estimate adjusted hazard ratios (HRs) and 95% CIs of the relationships between physical activity with incidence of 15 types of cancer. Dose-response relationships were modeled with restricted cubic spline functions that compared 7.5, 15.0, 22.5, and 30.0 MET hours/week to no leisure-time physical activity, and statistically significant associations were determined using tests for trend (P < .05) and 95% CIs (< 1.0).RESULTS: A total of 755,459 participants (median age, 62 years [range, 32-91 years]; 53% female) were followed for 10.1 years, and 50,620 incident cancers accrued. Engagement in recommended amounts of activity (7.5-15 MET hours/week) was associated with a statistically significant lower risk of 7 of the 15 cancer types studied, including colon (8%-14% lower risk in men), breast (6%-10% lower risk), endometrial (10%-18% lower risk), kidney (11%-17% lower risk), myeloma (14%-19% lower risk), liver (18%-27% lower risk), and non-Hodgkin lymphoma (11%-18% lower risk in women). The dose response was linear in shape for half of the associations and nonlinear for the others. Results for moderate- and vigorous-intensity leisure-time physical activity were mixed. Adjustment for body mass index eliminated the association with endometrial cancer but had limited effect on other cancer types.CONCLUSION: Health care providers, fitness professionals, and public health practitioners should encourage adults to adopt and maintain physical activity at recommended levels to lower risks of multiple cancers. 
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Cancer och onkologi0 (SwePub)302032 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cancer and Oncology0 (SwePub)302032 hsv//eng
7001 a Moore, Steven C.u NCI, Div Canc Epidemiol & Genet, Metab Epidemiol Branch, Bethesda, MD 20892 USA4 aut
7001 a Arem, Hannahu George Washington Univ, Sch Publ Hlth, Dept Epidemiol, Washington, DC USA4 aut
7001 a Cook, Michael B.u NCI, Div Canc Epidemiol & Genet, Metab Epidemiol Branch, Bethesda, MD 20892 USA4 aut
7001 a Trabert, Brittonu NCI, Div Canc Epidemiol & Genet, Metab Epidemiol Branch, Bethesda, MD 20892 USA4 aut
7001 a Håkansson, Niclasu Karolinska Institutet4 aut
7001 a Larsson, Susanna C.u Karolinska Institutet,Uppsala universitet,Ortopedi,Karolinska Inst, Inst Environm Med, Unit Cardiovasc & Nutr Epidemiol, Stockholm, Sweden4 aut0 (Swepub:uu)susla720
7001 a Wolk, Alicjau Karolinska Institutet,Uppsala universitet,Ortopedi,Karolinska Inst, Inst Environm Med, Unit Cardiovasc & Nutr Epidemiol, Stockholm, Sweden4 aut0 (Swepub:uu)alwol516
7001 a Gapstur, Susan M.u Amer Canc Soc, Behav & Epidemiol Res, Atlanta, GA 30329 USA4 aut
7001 a Lynch, Brigid M.u Canc Council Victoria, Canc Epidemiol Div, Melbourne, Vic, Australia;Univ Melbourne, Ctr Epidemiol & Biostat, Sch Populat & Global Hlth, Melbourne, Vic, Australia;Baker Heart & Diabet Inst, Phys Act Lab, Melbourne, Vic, Australia4 aut
7001 a Milne, Roger L.u Canc Council Victoria, Canc Epidemiol Div, Melbourne, Vic, Australia;Univ Melbourne, Ctr Epidemiol & Biostat, Sch Populat & Global Hlth, Melbourne, Vic, Australia;Monash Univ, Sch Clin Sci, Precis Med, Monash Hlth, Melbourne, Vic, Australia4 aut
7001 a Freedman, Neal D.u NCI, Div Canc Epidemiol & Genet, Metab Epidemiol Branch, Bethesda, MD 20892 USA4 aut
7001 a Huang, Wen-Yiu NCI, Div Canc Epidemiol & Genet, Metab Epidemiol Branch, Bethesda, MD 20892 USA4 aut
7001 a de Gonzalez, Amy Berringtonu NCI, Div Canc Epidemiol & Genet, Radiat Epidemiol Branch, Bethesda, MD 20892 USA4 aut
7001 a Kitahara, Cari M.u NCI, Div Canc Epidemiol & Genet, Radiat Epidemiol Branch, Bethesda, MD 20892 USA4 aut
7001 a Linet, Martha S.u Karolinska Institutet4 aut
7001 a Shiroma, Eric J.u NIA, Lab Epidemiol & Populat Sci, Baltimore, MD 21224 USA4 aut
7001 a Sandin, Svenu Karolinska Inst, Dept Med Epidemiol & Biostat, Stockholm, Sweden;Icahn Sch Med Mt Sinai, Dept Psychiat, New York, NY 10029 USA;Seaver Autism Ctr Res & Treatment Mt Sinai, New York, NY USA4 aut
7001 a Patel, Alpa, Vu Amer Canc Soc, Behav & Epidemiol Res, Atlanta, GA 30329 USA4 aut
7001 a Lee, I-Minu Brigham & Womens Hosp, 75 Francis St, Boston, MA 02115 USA;Harvard Med Sch, Harvard TH Chan Sch Publ Hlth, Boston, MA 02115 USA4 aut
7102 a NCI, Div Canc Epidemiol & Genet, Metab Epidemiol Branch, Bethesda, MD 20892 USAb George Washington Univ, Sch Publ Hlth, Dept Epidemiol, Washington, DC USA4 org
7730 t Journal of Clinical Oncologyd : AMER SOC CLINICAL ONCOLOGYg 38:7, s. 686-697q 38:7<686-697x 0732-183Xx 1527-7755
8564 u https://doi.org/10.1200/JCO.19.02407y Fulltext
8564 u https://uu.diva-portal.org/smash/get/diva2:1427953/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-409789
8564 8u https://doi.org/10.1200/JCO.19.02407
8564 8u http://kipublications.ki.se/Default.aspx?queryparsed=id:143285709

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