onr:"swepub:oai:DiVA.org:uu-455822"
Sökning: onr:"swepub:oai:DiVA.org:uu-455822" > Disentangling adapt...
- 1 av 1
- Föregående post
- Nästa post
- Till träfflistan
| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 04251naa a2200457 4500 | |
| 001 | oai:DiVA.org:uu-455822 | |
| 003 | SwePub | |
| 008 | 211011s2021 | |||||||||||000 ||eng| | |
| 024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-4558222 URI |
| 024 | 7 | a https://doi.org/10.1111/1755-0998.134422 DOI |
| 040 | a (SwePub)uu | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a art2 swepub-publicationtype |
| 100 | 1 | a Leigh, Deborah M.u WSL Swiss Federal Research Institute Birmensdorf Switzerland4 aut |
| 245 | 1 0 | a Disentangling adaptation from drift in bottlenecked and reintroduced populations of Alpine ibex |
| 264 | c 2021-06-24 | |
| 264 | 1 | b John Wiley & Sons,c 2021 |
| 338 | a electronic2 rdacarrier | |
| 520 | a Identifying local adaptation in bottlenecked species is essential for conservation management. Selection detection methods have an important role in species management plans, assessments of adaptive capacity, and looking for responses to climate change. Yet, the allele frequency changes exploited in selection detection methods are similar to those caused by the strong neutral genetic drift expected during a bottleneck. Consequently, it is often unclear what accuracy selection detection methods have across bottlenecked populations. In this study, simulations were used to explore if signals of selection could be confidently distinguished from genetic drift across 23 bottlenecked and reintroduced populations of Alpine ibex (Capra ibex). The meticulously recorded demographic history of the Alpine ibex was used to generate comprehensive simulated SNP data. The simulated SNPs were then used to benchmark the confidence we could place in outliers identified in empirical Alpine ibex RADseq derived SNP data. Within the simulated data set, the false positive rates were high for all selection detection methods (FST outlier scans and Genetic-Environment Association analyses) but fell substantially when two or more methods were combined. True positive rates were consistently low and became negligible with increased stringency. Despite finding many outlier loci in the empirical Alpine ibex SNPs, none could be distinguished from genetic drift-driven false positives. Unfortunately, the low true positive rate also prevents the exclusion of recent local adaptation within the Alpine ibex. The baselines and stringent approach outlined here should be applied to other bottlenecked species to ensure the risk of false positive, or negative, signals of selection are accounted for in conservation management plans. | |
| 650 | 7 | a NATURVETENSKAPx Biologix Evolutionsbiologi0 (SwePub)106152 hsv//swe |
| 650 | 7 | a NATURAL SCIENCESx Biological Sciencesx Evolutionary Biology0 (SwePub)106152 hsv//eng |
| 653 | a Genetics | |
| 653 | a Ecology | |
| 653 | a Evolution | |
| 653 | a Behavior and Systematics | |
| 653 | a Biotechnology | |
| 653 | a Biologi | |
| 653 | a Biology | |
| 700 | 1 | a Lischer, Heidi E. L.u Interfaculty Bioinformatics Unit University of Bern Bern Switzerland;Swiss Institute of Bioinformatics Lausanne Switzerland4 aut |
| 700 | 1 | a Guillaume, Frédéricu Department of Evolutionary Biology and Environmental Studies University of Zurich Zurich Switzerland4 aut |
| 700 | 1 | a Grossen, Christineu Department of Evolutionary Biology and Environmental Studies University of Zurich Zurich Switzerland4 aut |
| 700 | 1 | a Günther, Torstenu Uppsala universitet,Människans evolution4 aut0 (Swepub:uu)torgu835 |
| 710 | 2 | a WSL Swiss Federal Research Institute Birmensdorf Switzerlandb Interfaculty Bioinformatics Unit University of Bern Bern Switzerland;Swiss Institute of Bioinformatics Lausanne Switzerland4 org |
| 773 | 0 | t Molecular Ecology Resourcesd : John Wiley & Sonsg 21:7, s. 2350-2363q 21:7<2350-2363x 1755-098Xx 1755-0998 |
| 856 | 4 | u https://doi.org/10.1111/1755-0998.13442y Fulltext |
| 856 | 4 | u https://uu.diva-portal.org/smash/get/diva2:1602136/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print |
| 856 | 4 | u https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/1755-0998.13442 |
| 856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-455822 |
| 856 | 4 8 | u https://doi.org/10.1111/1755-0998.13442 |
Hitta via bibliotek
- Molecular Ecology Resources (Sök värdpublikationen i LIBRIS)
Till lärosätets databas
- 1 av 1
- Föregående post
- Nästa post
- Till träfflistan
Hitta mer i SwePub
- Av författaren/redakt...
- Leigh, Deborah M ...
- Lischer, Heidi E ...
- Guillaume, Frédé ...
- Grossen, Christi ...
- Günther, Torsten
- Om ämnet
-
- NATURVETENSKAP
- NATURVETENSKAP
- och Biologi
- och Evolutionsbiolog ...
- Artiklar i publikationen
- Molecular Ecolog ...
- Av lärosätet
- Uppsala universitet
Sök utanför SwePub
- Sök vidare i:
- Google Book Search
- Google Scholar
Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.
- Copyright © LIBRIS - Nationella bibliotekssystem
- LIBRIS.kb.se
