Validation of a handheld single-lead ECG algorithm for atrial fibrillation detection after coronary revascularization

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Fältnamn	Indikatorer	Metadata
000		05202naa a2200541 4500
001		oai:gup.ub.gu.se/326883
003		SwePub
008		240528s2023 \| \|\|\|\|\|\|\|\|\|\|\|000 \|\|eng\|
009		oai:DiVA.org:oru-106034
009		oai:prod.swepub.kib.ki.se:152684044
024	7	a https://gup.ub.gu.se/publication/3268832 URI
024	7	a https://doi.org/10.1111/pace.147452 DOI
024	7	a https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-1060342 URI
024	7	a http://kipublications.ki.se/Default.aspx?queryparsed=id:1526840442 URI
040		a (SwePub)gud (SwePub)orud (SwePub)ki
041		a eng
042		9 SwePub
072	7	a ref2 swepub-contenttype
072	7	a art2 swepub-publicationtype
100	1	a Skröder, Sofia,d 1995-u Örebro universitet,Institutionen för medicinska vetenskaper,Centre for Clinical Research and Education, Region Värmland, Karlstad, Sweden4 aut0 (Swepub:oru)sisr
245	1 0	a Validation of a handheld single-lead ECG algorithm for atrial fibrillation detection after coronary revascularization
264	1	b Wiley-Blackwell Publishing Inc.c 2023
500		a Funding agency:Centre for Clinical Research and Education, Region Värmland
520		a BackgroundAtrial fibrillation (AF) is a rapidly increasing global public health concern entailing a high risk for ischemic stroke that can largely be avoided with anticoagulation therapy. AF is often underdiagnosed and there is a need for a reliable method of detection in individuals with additional risk factors for stroke such as coronary artery disease. We aimed to validate an automatic rhythm interpretation algorithm in thumb ECG in subjects with recent coronary revascularization. MethodsThumb ECG, a patient-operated handheld single-lead ECG recording device with an automatic interpretation algorithm, was performed three times daily for a month after coronary revascularization and 2-week periods 3, 12, and 24 months post-procedure. The detection of AF by the automatic algorithm on subject and single-strip ECG level was compared to manual interpretation. Results48,308 of 30 s thumb ECG recordings from 255 subjects (mean 212 +/- 3.5 recordings per subject) were retrieved from a database (AF 47 subjects/655 recordings; non-AF 208 subjects/47,653 recordings). The algorithm sensitivity at subject level was 100%, specificity 11.2%, positive predictive value (PPV) 20.2%, and negative predictive value (NPV) 100%. At the single-strip ECG level, sensitivity was 87.6%, specificity 94.0%, PPV 16.8%, and NPV 99.8%. The most common reasons for false positive results were technical disturbance and frequent ectopic beats. ConclusionsThe automatic interpretation algorithm in a handheld thumb ECG device can rule out AF in patients recently undergoing coronary revascularization with high accuracy, but manual confirmation is needed to confirm the diagnose of AF because of high false positive rates.
650	7	a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kardiologi0 (SwePub)302062 hsv//swe
650	7	a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cardiac and Cardiovascular Systems0 (SwePub)302062 hsv//eng
653		a arrhythmia
653		a atrial fibrillation
653		a cardiac electrophysiology
653		a coronary
653		a artery disease
653		a coronary revascularization
653		a electrocardiography
653		a Cardiovascular System & Cardiology
653		a Engineering
653		a arrhythmia
700	1	a Wickbom, Anders,d 1987-u Örebro universitet,Institutionen för medicinska vetenskaper,Department of Cardiothoracic and Vascular Surgery, Örebro University Hospital, Örebro, Sweden4 aut0 (Swepub:oru)aswm
700	1	a Björkenheim, Anna,d 1980-u Örebro universitet,Institutionen för medicinska vetenskaper,Region Örebro län,Department of Cardiology4 aut0 (Swepub:oru)anbm
700	1	a Ahlsson, A.u Karolinska Institutet4 aut
700	1	a Poci, Dritan,d 1969u Örebro universitet,Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine,Institutionen för medicinska vetenskaper,Department of Clinical Physiology, Sahlgrenska University Hospital, Gothenburg, Sweden; Department of Molecular and Clinical Medicine, Institution for Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden4 aut0 (Swepub:oru)dnpi
700	1	a Fengsrud, Espen,d 1970-u Örebro universitet,Institutionen för medicinska vetenskaper,Department of Cardiology, Örebro University Hospital, Örebro, Sweden4 aut0 (Swepub:oru)efd
710	2	a Örebro universitetb Institutionen för medicinska vetenskaper4 org
773	0	t Pace-Pacing and Clinical Electrophysiologyd : Wiley-Blackwell Publishing Inc.g 46:7, s. 782-787q 46:7<782-787x 0147-8389x 1540-8159
856	4	u https://doi.org/10.1111/pace.14745y Fulltext
856	4 8	u https://gup.ub.gu.se/publication/326883
856	4 8	u https://doi.org/10.1111/pace.14745
856	4 8	u https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-106034
856	4 8	u http://kipublications.ki.se/Default.aspx?queryparsed=id:152684044

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