onr:"swepub:oai:lup.lub.lu.se:10bb9485-a2a5-4e31-ab84-4606ce28838e"
Search: onr:"swepub:oai:lup.lub.lu.se:10bb9485-a2a5-4e31-ab84-4606ce28838e" > Habitual dietary in...
- 1 of 1
- Previous record
- Next record
- To hitlist
Habitual dietary intake versus glucose tolerance, insulin sensitivity and insulin secretion in postmenopausal women
-
- Larsson, Hillevi (author)
- Lund University,Lunds universitet,Institutionen för kliniska vetenskaper, Malmö,Medicinska fakulteten,Department of Clinical Sciences, Malmö,Faculty of Medicine,Skåne University Hospital
-
- Elmstǎhl, S. (author)
- Lund University,Lunds universitet,Geriatrik,Forskargrupper vid Lunds universitet,Geriatric Medicine,Lund University Research Groups,Geriatrics,Skåne University Hospital
-
- Berglund, G. (author)
- Lund University,Lunds universitet,Internmedicin - epidemiologi,Forskargrupper vid Lunds universitet,Internal Medicine - Epidemiology,Lund University Research Groups,Skåne University Hospital
- show more...
- show less...
- (creator_code:org_t)
- 2009-01-23
- 1999
- English 11 s.
- In: Journal of Internal Medicine. - : Wiley. - 1365-2796 .- 0954-6820. ; 245:6, s. 581-591
- Journal article (peer-reviewed)
Abstract
Subject headings
Close
- Objective. The major aim was to study the relation between habitual dietary intake and glucose tolerance, insulin sensitivity and insulin secretion in postmenopausal women. Dietary intake was also compared between women with normal (NGT) or impaired glucose tolerance (IGT). Design. Habitual dietary intake was studied using a modified diet history method, from which the energy, carbohydrate, fat and protein intake was calculated. Glucose tolerance was determined as the 2 h glucose value after a 75 g oral glucose tolerance test. Insulin sensitivity was studied with a euglycemic, hyperinsulinaemic clamp, whilst insulin secretion was measured as the acute (2-5 min) response to iv arginine (5 g) at fasting, 14 and >25 mmol L-1 glucose. Setting. Clinical research unit at the University Hospital in Malmo Sweden. Subjects. A total of 74 women (mean ± SD age 58.7 ± 0.4 years). Results. In the entire group, the 2 h glucose level correlated with polyunsaturated fat intake (PUFA, r = 0.41, P < 0.001), and negatively with carbo- hydrate intake (r = -0.23, P = 0.05). The relation between 2 h glucose and PUFA was independent of body fat content and insulin sensitivity in a multivariate model. Insulin sensitivity correlated with energy intake (r = 0.31. P = 0.007) and PUFA (r = 0.27, P = 0.022). However, these correlations were not significant after adjustment for body fat content in a multivariate model. There were no correlations between insulin secretory variables and habitual dietary intake. Of the 74 women. 60 had NGT and 14 had IGT. The NGT and IGT groups did not differ in intakes of total energy, carbohydrate or protein. The IGT women had higher intake of PUFA (P = 0.003), whilst the total, saturated and monounsaturated fat intake did not differ between the groups. Conclusion. Dietary parameters are not independently associated with insulin sensitivity or insulin secretion in postmenopausal women. Furthermore, dietary habits are largely similar in women with NGT and IGT, although subtle differences cannot be excluded due to the small study size. Therefore, habitual intake of total carbohydrate or total fat seems not to be the major determinant of glucose tolerance in nondiabetic Caucasian postmenopausal women.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Näringslära (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Nutrition and Dietetics (hsv//eng)
Keyword
- Diet
- Glucose tolerance
- Insulin secretion
- Insulin sensitivity
Publication and Content Type
- art (subject category)
- ref (subject category)
Find in a library
- Journal of Internal Medicine (Search for host publication in LIBRIS)
To the university's database
- 1 of 1
- Previous record
- Next record
- To hitlist
Find more in SwePub
- By the author/editor
- Larsson, Hillevi
- Elmstǎhl, S.
- Berglund, G.
- Ahrén, B.
- About the subject
-
- MEDICAL AND HEALTH SCIENCES
- MEDICAL AND HEAL ...
- and Health Sciences
- and Nutrition and Di ...
- Articles in the publication
- Journal of Inter ...
- By the university
- Lund University
Search outside SwePub
- Extend your search to:
- Google Book Search
- Google Scholar
Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.
- Copyright © LIBRIS - National Library Systems
- LIBRIS.kb.se
