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Dynamic anthropomorphic thorax phantom for quality assurance of motion management in radiotherapy

Abdollahi, Sara (författare)
Ferdowsi University of Mashhad,University Hospital of Zurich
Mowlavi, Ali Asghar (författare)
University of Montreal
Yazdi, Mohammad Hadi Hadizadeh (författare)
Ferdowsi University of Mashhad
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Ceberg, Sofie (författare)
Lund University,Lunds universitet,Medicinsk strålningsfysik, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Radiotherapy Physics,Forskargrupper vid Lunds universitet,LUCC: Lunds universitets cancercentrum,Övriga starka forskningsmiljöer,Medical Radiation Physics, Lund,Section V,Department of Clinical Sciences, Lund,Faculty of Medicine,Lund University Research Groups,LUCC: Lund University Cancer Centre,Other Strong Research Environments
Aznar, Marianne Camille (författare)
University of Manchester
Tabrizi, Fatemeh Varshoee (författare)
Salek, Roham (författare)
Mashhad University of Medical Sciences
Guckenberger, Matthias (författare)
University Hospital of Zurich
Tanadini-Lang, Stephanie (författare)
University Hospital of Zurich
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 (creator_code:org_t)
2024
2024
Engelska.
Ingår i: Physics and imaging in radiation oncology. - 2405-6316. ; 30
  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
Stäng  
  • Background and purpose: Motion management techniques are important to spare the healthy tissue adequately. However, they are complex and need dedicated quality assurance. The aim of this study was to create a dynamic phantom designed for quality assurance and to replicate a patient's size, anatomy, and tissue density. Materials and methods: A computed tomography (CT) scan of a cancer patient was used to create molds for the lungs, heart, ribs, and vertebral column via additive manufacturing. A pump system and software were developed to simulate respiratory dynamics. The extent of respiratory motion was quantified using a 4DCT scan. End-to-end tests were conducted to evaluate two motion management techniques for lung stereotactic body radiotherapy (SBRT). Results: The chest wall moved between 4 mm and 13 mm anteriorly and 2 mm to 7 mm laterally during the breathing. The diaphragm exhibited superior-inferior movement ranging from 5 mm to 16 mm in the left lung and 10 mm to 36 mm in the right lung. The left lung tumor displaced ± 7 mm superior-inferiorly and anterior-posteriorly. The CT numbers were for lung: −716 ± 108 HU (phantom) and −713 ± 70 HU (patient); bone: 460 ± 20 HU (phantom) and 458 ± 206 HU (patient); soft tissue: 92 ± 9 HU (phantom) and 60 ± 25 HU (patient). The end-to-end testing showed an excellent agreement between the measured and the calculated dose for ion chamber and film dosimetry. Conclusions: The phantom is recommended for quality assurance, evaluating the institution's specific planning and motion management strategies either through end-to-end testing or as an external audit phantom.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Radiologi och bildbehandling (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Radiology, Nuclear Medicine and Medical Imaging (hsv//eng)

Nyckelord

Dynamic anthropomorphic phantom
End-to-end test
Lung SBRT

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