Temporal trends in the proportion cured for cancer of the colon and rectum: a population-based study using data from the Finnish Cancer Registry

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Fältnamn	Indikatorer	Metadata
000		03289naa a2200457 4500
001		oai:DiVA.org:uu-102519
003		SwePub
008		090507s2007 \| \|\|\|\|\|\|\|\|\|\|\|000 \|\|eng\|
009		oai:prod.swepub.kib.ki.se:115965500
024	7	a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-1025192 URI
024	7	a https://doi.org/10.1002/ijc.229482 DOI
024	7	a http://kipublications.ki.se/Default.aspx?queryparsed=id:1159655002 URI
040		a (SwePub)uud (SwePub)ki
041		a engb eng
042		9 SwePub
072	7	a ref2 swepub-contenttype
072	7	a art2 swepub-publicationtype
100	1	a Lambert, Paul C.u Karolinska Institutet4 aut
245	1 0	a Temporal trends in the proportion cured for cancer of the colon and rectum :b a population-based study using data from the Finnish Cancer Registry
264		c 2007-07-19
264	1	b Wiley,c 2007
338		a print2 rdacarrier
520		a Colorectal cancer is the third most common cancer worldwide and the second most common cancer in Europe. Cumulative relative survival curves for both cancer of the colon and cancer of the rectum generally plateau after approximately 6-8 years. When this occurs, "population" or "statistical" cure is reached. We analyzed data from the Finnish Cancer Registry over a 50-year period using methods that simultaneously estimate the proportion of patients cured of disease (the cure fraction) and the survival time distribution of the "uncured" group. Our primary aim was to investigate temporal trends in the cure fraction and median survival of the uncured by age group for both cancer of the colon and rectum. For both cancers, the cure fraction has increased dramatically over time for all age groups. However, the difference in the cure fraction between age groups has reduced over time, particularly for cancer of the colon. Median survival in the uncured has also increased over time in all age groups but there still remains an inverse relationship between age and median survival, with shorter median survival with increasing age. The reasons for these impressive increases in patient survival are complex, but are highly likely to be strongly related to many improvements in cancer care over this same time period.
653		a colorectal cancer
653		a cure models
653		a survival
653		a colon cancer
653		a rectum cancer
653		a MEDICINE
653		a MEDICIN
700	1	a Dickman, Paul W.u Karolinska Institutet4 aut
700	1	a Österlund, Pia4 aut
700	1	a Andersson, Thereseu Karolinska Institutet4 aut
700	1	a Sankila, Risto4 aut
700	1	a Glimelius, Bengtu Karolinska Institutet,Uppsala universitet,Institutionen för onkologi, radiologi och klinisk immunologi4 aut0 (Swepub:uu)bengglim
710	2	a Karolinska Institutetb Institutionen för onkologi, radiologi och klinisk immunologi4 org
773	0	t International Journal of Cancerd : Wileyg 121:9, s. 2052-2059q 121:9<2052-2059x 0020-7136x 1097-0215
856	4	u https://www.onlinelibrary.wiley.com/doi/pdfdirect/10.1002/ijc.22948
856	4 8	u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-102519
856	4 8	u https://doi.org/10.1002/ijc.22948
856	4 8	u http://kipublications.ki.se/Default.aspx?queryparsed=id:115965500

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Av författaren/redakt...: Lambert, Paul C.; Dickman, Paul W.; Österlund, Pia; Andersson, There ...; Sankila, Risto; Glimelius, Bengt

Artiklar i publikationen: International Jo ...

Av lärosätet: Uppsala universitet; Karolinska Institutet

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