2018 EHRA expert consensus statement on lead extraction: recommendations on definitions, endpoints, research trial design, and data collection requirements for clinical scientific studies and registries: endorsed by APHRS/HRS/LAHRS

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Fältnamn	Indikatorer	Metadata
000		05066naa a2200805 4500
001		oai:DiVA.org:uu-365928
003		SwePub
008		181115s2018 \| \|\|\|\|\|\|\|\|\|\|\|000 \|\|eng\|
024	7	a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3659282 URI
024	7	a https://doi.org/10.1093/europace/euy0502 DOI
040		a (SwePub)uu
041		a engb eng
042		9 SwePub
072	7	a ref2 swepub-contenttype
072	7	a art2 swepub-publicationtype
100	1	a Bongiorni, Maria G4 aut
245	1 0	a 2018 EHRA expert consensus statement on lead extraction :b recommendations on definitions, endpoints, research trial design, and data collection requirements for clinical scientific studies and registries: endorsed by APHRS/HRS/LAHRS
264		c 2018-03-16
264	1	b Oxford University Press (OUP),c 2018
338		a print2 rdacarrier
520		a The number of cardiac implantable electronic device (CIED) implantations has increased over recent years as a result of population growth, increasing life expectancy, adoption of guidelines, and better access to healthcare. Transvenous lead extraction (TLE), as a part of an overall lead management strategy, has also been increasing, not only as a consequence of this growth, but also because of increasing rates of infection, lead failure, awareness of indications for lead management, and development of extraction tools. Clinical research is essential for understanding efficacy and risks of TLE, which has important implications regarding decision-making and therapeutic strategies in patients who are candidates for this procedure. Data on TLE have mainly come from retrospective series, with variable reporting of endpoints. Recently, the ELECTRa registry conducted by the European Heart Rhythm Association (EHRA), has reported the largest prospective experience on lead extraction published to date in 3555 patients recruited from 19 European countries. There remain unresolved issues, which is a strong incentive for conducting further specifically-designed clinical trials to answer important questions in this area. In addition to clinical studies, national registries are potentially useful for evaluating epidemiology of TLE as well as for quality control and understanding resource implications. Standardization of definitions and reporting of parameters are paramount in order to analyse, compare, and pool data for scientific purposes. Expert consensus statements on lead extraction have been published by the Heart Rhythm Society (HRS) in 2009 and 2017, and by EHRA in 2012. Experience from the ELECTRa registry has been valuable for identifying challenges faced with conducting scientific studies in this field, and provides a framework for future endeavours.This writing group has been commissioned by EHRA to provide recommendations for designing scientific studies, reports and registries relating to lead extraction.
650	7	a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kardiologi0 (SwePub)302062 hsv//swe
650	7	a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cardiac and Cardiovascular Systems0 (SwePub)302062 hsv//eng
653		a Cardiac implantable electronic device
653		a Pacemaker
653		a Implantable cardioverter-defibrillator
653		a Lead-related complications
653		a Infection
653		a Lead extraction
653		a Lead extraction techniques
653		a Indications
653		a Outcome
653		a Recommendations
653		a Trial design
653		a Registry
653		a Training
653		a EHRA consensus statement
653		a Cardiology
653		a Kardiologi
700	1	a Burri, Haran4 aut
700	1	a Deharo, Jean C.4 aut
700	1	a Starck, Christoph4 aut
700	1	a Kennergren, Charles4 aut
700	1	a Saghy, Laszlo4 aut
700	1	a Rao, Archana4 aut
700	1	a Tascini, Carlo4 aut
700	1	a Lever, Nigel4 aut
700	1	a Kutarski, Andrzej4 aut
700	1	a Fernandez Lozano, Ignacio4 aut
700	1	a Strathmore, Neil4 aut
700	1	a Costa, Roberto4 aut
700	1	a Epstein, Laurence4 aut
700	1	a Love, Charles4 aut
700	1	a Blomström-Lundqvist, Carinau Uppsala universitet,Kardiologi-arrytmi4 aut0 (Swepub:uu)carinabl
700	1	a Fauchier, Laurent4 aut
700	1	a Defaye, Pascal4 aut
700	1	a Arnar, David O.4 aut
700	1	a Klug, Didier4 aut
700	1	a Boveda, Serge4 aut
700	1	a Cosedis Nielsen, Jens4 aut
700	1	a Boriani, Giuseppe4 aut
700	1	a Zhang, Shu4 aut
700	1	a Martin, Andrew Paul4 aut
700	1	a Prutkin, Jordan M.4 aut
700	1	a de Zuloaga, Claudio4 aut
710	2	a Uppsala universitetb Kardiologi-arrytmi4 org
773	0	t Europaced : Oxford University Press (OUP)g 20:7q 20:7x 1099-5129x 1532-2092
856	4	u https://iris.unimore.it/bitstream/11380/1167965/2/euy050%281%29.pdf
856	4 8	u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-365928
856	4 8	u https://doi.org/10.1093/europace/euy050

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