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LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00004385naa a2200469 4500
001oai:DiVA.org:liu-138923
003SwePub
008170627s2017 | |||||||||||000 ||eng|
024a https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-1389232 URI
024a https://doi.org/10.1016/j.ijantimicag.2016.12.0182 DOI
040 a (SwePub)liu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
100a Bi, Zhenwangu Shandong Centre Disease Control and Prevent, Peoples R China4 aut
2451 0a Prevalence of the mcr-1 colistin resistance gene in extended-spectrum beta-lactamase-producing Escherichia coli from human faecal samples collected in 2012 in rural villages in Shandong Province, China
264 1b ELSEVIER SCIENCE BV,c 2017
338 a print2 rdacarrier
500 a Funding Agencies|National Natural Science Foundation of China [71073098]; Swedish International Development Cooperation Agency; Swedish Institute for Communicable Disease Control [2010-001861]
520 a Since its initial discovery in China in 2015, the plasmid-mediated colistin resistance gene mcr-1 has been reported in Escherichia coli isolated from clinical samples, animals and meat worldwide. In this study, 706 extended-spectrum beta-lactamase (ESBL)-producing E. coli from 411 persons were detected in a collection of faecal samples from 1000 rural residents in three counties in Shandong Province, China. These isolates were screened for mcr-1 and phenotypic colistin resistance. The gene was found in 3.5% of the isolates (from 4.9% of persons) from all three counties. All isolates with phenotypic colistin resistance carried mcr-1. These data indicate that commensal carriage of ESBL-producing E. coli with mcr-1 among persons in rural China was already present in 2012 and that mcr-1 was the most important colistin resistance mechanism. Interventions are necessary to minimise further dissemination of mcr-1, which would limit the future usefulness of colistin as a last-resort antibiotic. (C) 2017 Elsevier B.V. and International Society of Chemotherapy. All rights reserved.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Mikrobiologi inom det medicinska området0 (SwePub)301092 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Microbiology in the medical area0 (SwePub)301092 hsv//eng
653 a Drug resistance; Bacteria; Colistin; Escherichia coli; Rural China
700a Berglund, Björnu Linköpings universitet,Avdelningen för mikrobiologi och molekylär medicin,Medicinska fakulteten4 aut0 (Swepub:liu)bjobe50
700a Sun, Qiangu Shandong University, Peoples R China; Shandong University, Peoples R China4 aut
700a Nilsson, Maudu Linköpings universitet,Avdelningen för mikrobiologi och molekylär medicin,Medicinska fakulteten4 aut0 (Swepub:liu)mauni03
700a Chen, Baoliu Shandong Centre Disease Control and Prevent, Peoples R China4 aut
700a Tärnberg, Mariau Linköpings universitet,Avdelningen för mikrobiologi och molekylär medicin,Medicinska fakulteten4 aut0 (Swepub:liu)marta92
700a Ding, Liluu Shandong University, Peoples R China4 aut
700a Stalsby Lundborg, Ceciliau Karolinska Institute, Sweden4 aut
700a Bi, Zhenqiangu Shandong Centre Disease Control and Prevent, Peoples R China4 aut
700a Tomson, Goranu Karolinska Institute, Sweden4 aut
700a Yao, Jingjingu Shandong University, Peoples R China4 aut
700a Gu, Zhanyingu Shandong University, Peoples R China4 aut
700a Yin, Xiaou Jinan Central Hospital, Peoples R China4 aut
700a Kou, Zengqiangu Shandong Centre Disease Control and Prevent, Peoples R China4 aut
700a Nilsson, Lennart Eu Linköpings universitet,Avdelningen för mikrobiologi och molekylär medicin,Medicinska fakulteten4 aut0 (Swepub:liu)lenni43
710a Shandong Centre Disease Control and Prevent, Peoples R Chinab Avdelningen för mikrobiologi och molekylär medicin4 org
773t International Journal of Antimicrobial Agentsd : ELSEVIER SCIENCE BVg 49:4, s. 493-497q 49:4<493-497x 0924-8579x 1872-7913
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-138923
8564 8u https://doi.org/10.1016/j.ijantimicag.2016.12.018

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