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LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00003412naa a2200349 4500
001oai:gup.ub.gu.se/45662
003SwePub
008240528s2006 | |||||||||||000 ||eng|
009oai:prod.swepub.kib.ki.se:1942240
024a https://gup.ub.gu.se/publication/456622 URI
024a https://doi.org/10.1016/j.eururo.2005.12.0382 DOI
024a http://kipublications.ki.se/Default.aspx?queryparsed=id:19422402 URI
040 a (SwePub)gud (SwePub)ki
041 a eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
100a Hopfgarten, T.u Karolinska Institutet4 aut
2451 0a The choice between a therapy-induced long-term symptom and shortened survival due to prostate cancer
264 1b Elsevier BV,c 2006
520 a OBJECTIVES: A patient with newly diagnosed localized prostate cancer can choose from an array of therapies. A patient's willingness to trade life for freedom from therapy-induced long-term symptoms is poorly investigated. METHODS: In October 2002, we attempted to collect information from the 591 men who had been diagnosed and registered with prostate cancer in 1999 in Stockholm County. In a postal questionnaire, men were asked to balance absence or presence of certain therapy-induced long-term symptoms against varying lengths of survival gain as a consequence of the therapy. RESULTS: Information was provided by 511 (86%) of the 591 men. A large majority of the men participating in this study ended up in one of two extreme categories: either they accepted the therapy-induced symptom to gain survival or they did not. For fecal leakage, 78% of the men chose one of two extreme categories compared with 74% for urinary leakage, 71% for tender enlarged breasts, 73% for erectile dysfunction, and 78% for restricted diet. Thirty-seven percent of the men in the study were willing to accept fecal leakage if there was only the slightest chance to gain survival, comparing percentages for urinary leakage, tender enlarged breasts, restricted diet, and erectile dysfunction and were 48%, 53%, 55%, and 64%, respectively. CONCLUSION: Willingness to accept therapy-induced long-term symptoms to avoid a shortened survival due to prostate cancer varies dramatically among men with localized prostate cancer and a large majority of men are in one of two extreme categories. Among symptoms, long-term fecal leakage was the one fewest men were willing to accept to gain survival.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Cancer och onkologi0 (SwePub)302032 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cancer and Oncology0 (SwePub)302032 hsv//eng
700a Adolfsson, J.u Karolinska Institutet4 aut
700a Henningsohn, L.u Karolinska Institutet4 aut
700a Onelov, E.u Karolinska Institutet4 aut
700a Steineck, Gunnar,d 1952u Karolinska Institutet,Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper,Institute of Clinical Sciences4 aut0 (Swepub:gu)xstegu
710a Karolinska Institutetb Institutionen för kliniska vetenskaper4 org
773t Eur Urold : Elsevier BVg 50:2, s. 280-9q 50:2<280-9x 0302-2838
8564 8u https://gup.ub.gu.se/publication/45662
8564 8u https://doi.org/10.1016/j.eururo.2005.12.038
8564 8u http://kipublications.ki.se/Default.aspx?queryparsed=id:1942240

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