Current trends in the medical treatment of neuropathic low back pain: a Swedish registry-based study of 1.7 million people

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Fältnamn	Indikatorer	Metadata
000		04914naa a2200445 4500
001		oai:gup.ub.gu.se/339631
003		SwePub
008		240910s2024 \| \|\|\|\|\|\|\|\|\|\|\|000 \|\|eng\|
009		oai:DiVA.org:umu-227348
024	7	a https://gup.ub.gu.se/publication/3396312 URI
024	7	a https://doi.org/10.1186/s12891-024-07599-42 DOI
024	7	a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-2273482 URI
040		a (SwePub)gud (SwePub)umu
041		a eng
042		9 SwePub
072	7	a ref2 swepub-contenttype
072	7	a art2 swepub-publicationtype
100	1	a Nyqvist, Linusu Spine Unit, Department of Orthopedics, Umeå University Hospital, Umeå, Sweden4 aut
245	1 0	a Current trends in the medical treatment of neuropathic low back pain: a Swedish registry-based study of 1.7 million people
264	1	b BioMed Central (BMC),c 2024
520		a Background Low back pain, a common problem worldwide, causes more global disability than any other condition and is associated with high costs to society. This observational registry-based study describes the current trends in the medical treatment of neuropathic low back pain in the Swedish region of V & auml;stra G & ouml;taland, which has a population of 1.7 million. The study aims to; (1) identify the prevalence of neuropathic low back pain within the study population; (2) to explore the patterns of medical treatment utilization, including the prevalence and distribution of opioids (OG) and analgesics specified for neuropathic low back pain (NG) and (3) to evaluate the long-term trends and changes in medical treatment practice for neuropathic low back pain over the study period.Methods This study includes a descriptive analysis of aggregated data extracted from the Swedish primary care registry VEGA and the pharmaceutical prescription registry Digitalis between the years 2017 and 2021. The data were stratified by year, age, gender, pharmaceutical code (ATC), and sub-diagnoses and presented as the prevalence of unique patients retrieving prescribed medication within six months before or after a registered diagnosis of neuropathic low back pain. The pharmaceutical codes were furthermore grouped into two groups depending on their mechanism of action; opioid group (OG) and neuropathic group (NG).Results In all four diagnosis groups, more patients used opioid analgesics than neuropathic analgesics. The greatest difference between the opioid group and neuropathic group was in the lumbar spinal stenosis diagnosis group (67.1% vs. 40.6%), followed by the lumbar root canal stenosis diagnosis (65.9% vs. 44.2%), the nerve root and plexus compressions in intervertebral disc disorders diagnosis (57.5% vs. 40.8%), and lumbago with sciatica diagnosis (38.4% vs. 22.7%).Conclusions The trends suggest a general increase in the prescription rate and therefore patients' use of neuropathic analgesics for neuropathic pain associated with the studied diagnoses. However, opioid treatment remains the most common. The results indicate that the treatment for neuropathic low back pain needs to be improved.
650	7	a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Ortopedi0 (SwePub)302112 hsv//swe
650	7	a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Orthopaedics0 (SwePub)302112 hsv//eng
650	7	a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicin0 (SwePub)3022 hsv//swe
650	7	a MEDICAL AND HEALTH SCIENCESx Clinical Medicine0 (SwePub)3022 hsv//eng
653		a Neuropathic low back pain
653		a Radicular pain
653		a Opioids
653		a Neuropathic analgesics
653		a Pain therapy
653		a Neuropathic analgesics
700	1	a Åkerstedt, Josefinu Umeå universitet,Institutionen för diagnostik och intervention,Spine Unit, Department of Orthopedics, Umeå University Hospital, Umeå, Sweden4 aut0 (Swepub:umu)joak0027
700	1	a Thoreson, Olof,d 1981u Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för ortopedi,Institute of Clinical Sciences, Department of Orthopaedics,Department of Orthopedics, Institute of Clinical Sciences at Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; Research and Development Primary Health Care Center, Gothenburg, Sweden4 aut0 (Swepub:gu)xthool
710	2	a Spine Unit, Department of Orthopedics, Umeå University Hospital, Umeå, Swedenb Institutionen för diagnostik och intervention4 org
773	0	t BMC MUSCULOSKELETAL DISORDERSd : BioMed Central (BMC)g 25:1q 25:1x 1471-2474
856	4	u https://doi.org/10.1186/s12891-024-07599-4y Fulltext
856	4	u https://umu.diva-portal.org/smash/get/diva2:1878565/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print
856	4 8	u https://gup.ub.gu.se/publication/339631
856	4 8	u https://doi.org/10.1186/s12891-024-07599-4
856	4 8	u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-227348

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