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LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00005755naa a2200637 4500
001oai:DiVA.org:uu-315520
003SwePub
008170215s2012 | |||||||||||000 ||eng|
009oai:prod.swepub.kib.ki.se:125700684
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3155202 URI
0247 a https://doi.org/10.1164/rccm.201203-0501OC2 DOI
0247 a http://kipublications.ki.se/Default.aspx?queryparsed=id:1257006842 URI
040 a (SwePub)uud (SwePub)ki
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Neuman, Åsau Karolinska Institutet,Uppsala universitet,Pediatrik,Karolinska Inst, Inst Environm Med, SE-17177 Stockholm, Sweden.4 aut0 (Swepub:uu)asane642
2451 0a Maternal Smoking in Pregnancy and Asthma in Preschool Children A Pooled Analysis of Eight Birth Cohorts
264 1c 2012
338 a print2 rdacarrier
520 a Rationale: Although epidemiological studies suggest that exposure to maternal smoking during fetal and early life increases the risk of childhood wheezing and asthma, previous studies were not able to differentiate the effects of prenatal from postnatal exposure. Objectives: To assess the effect of exposure to maternal smoking only during pregnancy on wheeze and asthma among preschool-age children. Methods: A pooled analysis was performed based on individual participant data from eight European birth cohorts. Cohort-specific effects of maternal smoking during pregnancy, but not during the first year, on wheeze and asthma at 4 to 6 years of age were estimated using logistic regression and then combined using a random effects model. Adjustments were made for sex, parental education, parental asthma, birth weight, and siblings. Measurements and Main Results: Among the 21,600 children included in the analysis, 735 children (3.4%) were exposed to maternal smoking exclusively during pregnancy but not in the first year after birth. In the pooled analysis, maternal smoking only during pregnancy was associated with wheeze and asthma at 4 to 6 years of age, with adjusted odds ratios of 1.39 (95% confidence interval, 1.08-1.77) and 1.65 (95% confidence interval, 1.18-2.31), respectively. The likelihood to develop wheeze and asthma increased statistically significantly in a linear dose-dependent manner in relation to maternal daily cigarette consumption during the first trimester of pregnancy. Conclusions: Maternal smoking during pregnancy appears to increase the risk of wheeze and asthma among children who are not exposed to maternal smoking after birth.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Pediatrik0 (SwePub)302212 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Pediatrics0 (SwePub)302212 hsv//eng
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Lungmedicin och allergi0 (SwePub)302192 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Respiratory Medicine and Allergy0 (SwePub)302192 hsv//eng
653 a asthma
653 a cohort studies
653 a epidemiology
653 a preschool children
653 a tobacco smoking
7001 a Hohmann, Cynthiau Charite Univ Med Ctr, Inst Social Med Epidemiol & Hlth Econ, Berlin, Germany.4 aut
7001 a Orsini, Nicolau Karolinska Institutet4 aut
7001 a Pershagen, Goranu Karolinska Institutet4 aut
7001 a Eller, Esbenu Odense Univ Hosp, Dept Dermatol, DK-5000 Odense, Denmark.;Odense Univ Hosp, Allergy Ctr, DK-5000 Odense, Denmark.4 aut
7001 a Kjaer, Henrik Fomsgaardu Odense Univ Hosp, Hans Christian Andersen Childrens Hosp, DK-5000 Odense, Denmark.4 aut
7001 a Gehring, Ulrikeu Univ Utrecht, IRAS, Utrecht, Netherlands.4 aut
7001 a Granell, Raquelu Univ Bristol, Sch Social & Community Med, Bristol, Avon, England.4 aut
7001 a Henderson, Johnu Univ Bristol, Sch Social & Community Med, Bristol, Avon, England.4 aut
7001 a Heinrich, Joachimu German Res Ctr Environm Hlth, Helmholtz Zentrum Munchen, Inst Epidemiol 1, Neuherberg, Germany.4 aut
7001 a Lau, Susanneu Charite Univ Med Ctr, Dept Pediat Pneumol & Immunol, Berlin, Germany.4 aut
7001 a Nieuwenhuijsen, Marku Ctr Res Environm Epidemiol CREAL, Barcelona, Spain.;CIBERESP, Barcelona, Spain.;IMIM Hosp del Mar Inst, Barcelona, Spain.4 aut
7001 a Sunyer, Jordiu Ctr Res Environm Epidemiol CREAL, Barcelona, Spain.;CIBERESP, Barcelona, Spain.;IMIM Hosp del Mar Inst, Barcelona, Spain.;UPF, Barcelona, Spain.4 aut
7001 a Tischer, Christinau German Res Ctr Environm Hlth, Helmholtz Zentrum Munchen, Inst Epidemiol 1, Neuherberg, Germany.4 aut
7001 a Torrent, Matiesu CIBERESP, Barcelona, Spain.;Ib Salut, Area Salut Menorca, Palma De Mallorca, Spain.4 aut
7001 a Wahn, Ulrichu Charite Univ Med Ctr, Dept Pediat Pneumol & Immunol, Berlin, Germany.4 aut
7001 a Wijga, Alet H.u Natl Inst Publ Hlth & Environm RIVM, Ctr Prevent & Hlth Serv Res, Bilthoven, Netherlands.4 aut
7001 a Wickman, Magnusu Karolinska Institutet4 aut
7001 a Keil, Thomasu Charite Univ Med Ctr, Inst Social Med Epidemiol & Hlth Econ, Berlin, Germany.4 aut
7001 a Bergstrom, Annau Karolinska Institutet4 aut
7001 a the ENRICO, Consortium4 aut
7102 a Uppsala universitetb Pediatrik4 org
7730 t American Journal of Respiratory and Critical Care Medicineg 186:10, s. 1037-1043q 186:10<1037-1043x 1073-449Xx 1535-4970
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-315520
8564 8u https://doi.org/10.1164/rccm.201203-0501OC
8564 8u http://kipublications.ki.se/Default.aspx?queryparsed=id:125700684

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