Sökning: WFRF:(Xu Bingze) > Streptococcal Endo-...
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000 | 05146naa a2200601 4500 | |
001 | oai:lup.lub.lu.se:d566f7f9-1e9a-4428-b644-676331c8a722 | |
003 | SwePub | |
008 | 180724s2018 | |||||||||||000 ||eng| | |
009 | oai:prod.swepub.kib.ki.se:138720554 | |
009 | oai:DiVA.org:hh-48390 | |
009 | oai:DiVA.org:hh-48797 | |
024 | 7 | a https://lup.lub.lu.se/record/d566f7f9-1e9a-4428-b644-676331c8a7222 URI |
024 | 7 | a https://doi.org/10.3389/fimmu.2018.016232 DOI |
024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1387205542 URI |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:hh:diva-483902 URI |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:hh:diva-487972 URI |
040 | a (SwePub)lud (SwePub)kid (SwePub)hhd (SwePub)hh | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a art2 swepub-publicationtype |
072 | 7 | a ref2 swepub-contenttype |
100 | 1 | a Nandakumar, Kutty Selva,d 1965-u Karolinska Institutet,Southern Medical University, Guangzhou, China; Karolinska Institute, Stockholm, Sweden4 aut0 (Swepub:hh)kutnam |
245 | 1 0 | a Streptococcal Endo-β-N-Acetylglucosaminidase Suppresses Antibody-Mediated Inflammation In Vivo |
264 | c 2018-07-16 | |
264 | 1 | b Frontiers Media SA,c 2018 |
520 | a Endo-β-N-acetylglucosaminidase (EndoS) is a family 18 glycosyl hydrolase secreted by Streptococcus pyogenes. Recombinant EndoS hydrolyzes the β-1,4-di-N-acetylchitobiose core of the N-linked complex type glycan on the asparagine 297 of the γ-chains of IgG. Here, we report that EndoS and IgG hydrolyzed by EndoS induced suppression of local immune complex (IC)-mediated arthritis. A small amount (1 µg given i.v. to a mouse) of EndoS was sufficient to inhibit IgG-mediated arthritis in mice. The presence of EndoS disturbed larger IC lattice formation both in vitro and in vivo, as visualized with anti-C3b staining. Neither complement binding in vitro nor antigen-antibody binding per se were affected. Thus, EndoS could potentially be used for treating patients with IC-mediated pathology. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Immunologi inom det medicinska området0 (SwePub)301102 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Immunology in the medical area0 (SwePub)301102 hsv//eng |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Reumatologi och inflammation0 (SwePub)302102 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Rheumatology and Autoimmunity0 (SwePub)302102 hsv//eng |
653 | a arthritis | |
700 | 1 | a Collin, Mattiasu Lund University,Lunds universitet,Infektionsmedicin,Sektion III,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Infektion och immunmodulering,Forskargrupper vid Lunds universitet,Infection Medicine (BMC),Section III,Department of Clinical Sciences, Lund,Faculty of Medicine,Infection and immunomodulation,Lund University Research Groups,Lund University, Lund, Sweden4 aut0 (Swepub:lu)medk-mco |
700 | 1 | a Happonen, Kaisa E.u Lund University, Lund, Sweden; Salk Institute for Biological Studies, La Jolla, CA, United States4 aut0 (Swepub:lu)med-khp |
700 | 1 | a Lundström, Susanna L.u Karolinska Institutet,Karolinska Institute, Stockholm, Sweden4 aut |
700 | 1 | a Croxford, Allyson M.u Monash University, Clayton, VIC, Australia4 aut |
700 | 1 | a Xu, Bingzeu Karolinska Institutet,Karolinska Institute, Stockholm, Sweden4 aut |
700 | 1 | a Zubarev, Roman A.u Karolinska Institutet,Karolinska Institute, Stockholm, Sweden4 aut |
700 | 1 | a Rowley, Merrill J.u Monash University, Clayton, VIC, Australia4 aut |
700 | 1 | a Blom, Anna M.u Lund University,Lunds universitet,Proteinkemi, Malmö,Forskargrupper vid Lunds universitet,Protein Chemistry, Malmö,Lund University Research Groups,Lund University, Lund, Sweden4 aut0 (Swepub:lu)klke-abl |
700 | 1 | a Kjellman, Christianu Hansa Medical AB, Lund, Sweden4 aut |
700 | 1 | a Holmdahl, Rikardu Karolinska Institutet,Southern Medical University, Guangzhou, China; Karolinska Institute, Stockholm, Sweden4 aut |
710 | 2 | a Karolinska Institutetb Southern Medical University, Guangzhou, China; Karolinska Institute, Stockholm, Sweden4 org |
773 | 0 | t Frontiers in Immunologyd : Frontiers Media SAg 9q 9x 1664-3224 |
856 | 4 | u http://dx.doi.org/10.3389/fimmu.2018.01623x freey FULLTEXT |
856 | 4 | u https://www.frontiersin.org/articles/10.3389/fimmu.2018.01623/pdf |
856 | 4 | u https://doi.org/10.3389/fimmu.2018.01623y Fulltext |
856 | 4 | u https://hh.diva-portal.org/smash/get/diva2:1703108/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print |
856 | 4 | u https://hh.diva-portal.org/smash/get/diva2:1717785/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print |
856 | 4 8 | u https://lup.lub.lu.se/record/d566f7f9-1e9a-4428-b644-676331c8a722 |
856 | 4 8 | u https://doi.org/10.3389/fimmu.2018.01623 |
856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:138720554 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:hh:diva-48390 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:hh:diva-48797 |
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