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Sökning: WFRF:(Fored C. M.) > Risks of solid canc...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00006023naa a2200805 4500
001oai:DiVA.org:uu-76846
003SwePub
008060627s2005 | |||||||||||000 ||eng|
009oai:DiVA.org:umu-13363
009oai:lup.lub.lu.se:654a9037-d7fe-4a9f-ad75-a2d2c4624dc9
009oai:prod.swepub.kib.ki.se:1938210
009oai:DiVA.org:liu-33259
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-768462 URI
0247 a https://doi.org/10.1136/ard.2004.0339932 DOI
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-133632 URI
0247 a https://lup.lub.lu.se/record/2246812 URI
0247 a http://kipublications.ki.se/Default.aspx?queryparsed=id:19382102 URI
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-332592 URI
040 a (SwePub)uud (SwePub)umud (SwePub)lud (SwePub)kid (SwePub)liu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Askling, Ju Karolinska Institutet4 aut
2451 0a Risks of solid cancers in patients with rheumatoid arthritis and after treatment with tumour necrosis factor antagonists
264 1b BMJ,c 2005
338 a print2 rdacarrier
520 a BACKGROUND:Existing studies of solid cancers in rheumatoid arthritis (RA) reflect cancer morbidity up until the early 1990s in prevalent cohorts admitted to hospital during the 1980s.OBJECTIVE:To depict the cancer pattern of contemporary patients with RA, from updated risk data from prevalent and incident RA populations. To understand the risk of solid cancer after tumour necrosis factor (TNF) treatment by obtaining cancer data from cohorts treated in routine care rather than trials.METHODS:A population based study of three RA cohorts (one prevalent, admitted to hospital 1990-2003 (n = 53,067), one incident, diagnosed 1995-2003 (n = 3703), and one treated with TNF antagonists 1999-2003 (n = 4160)), which were linked with Swedish nationwide cancer and census registers and followed up for cancer occurrence through 2003.RESULTS:With 3379 observed cancers, the prevalent RA cohort was at marginally increased overall risk of solid cancer, with 20-50% increased risks for smoke related cancers and +70% increased risk for non-melanoma skin cancer, but decreased risk for breast (-20%) and colorectal cancer (-25%). With 138 cancers, the incident RA cohort displayed a similar cancer pattern apart from non-decreased risks for colorectal cancer. TNF antagonist treated patients displayed solid cancer (n = 67) risks largely similar to those of other patients with RA.CONCLUSION:The cancer pattern in patients treated with TNF antagonists mirrors those of other contemporary as well as historic RA cohorts. The consistent increase in smoking associated cancers in patients with RA emphasises the potential for smoking cessation as a cancer preventive measure in RA.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Reumatologi och inflammation0 (SwePub)302102 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Rheumatology and Autoimmunity0 (SwePub)302102 hsv//eng
653 a Adolescent
653 a Adult
653 a Aged
653 a Antirheumatic Agents/*adverse effects/therapeutic use
653 a Arthritis; Rheumatoid/*drug therapy/epidemiology
653 a Biological Response Modifiers/*adverse effects/therapeutic use
653 a Epidemiologic Methods
653 a Female
653 a Humans
653 a Male
653 a Middle Aged
653 a Neoplasms/*chemically induced/epidemiology
653 a Research Support; Non-U.S. Gov't
653 a Sweden/epidemiology
653 a Tumor Necrosis Factor-alpha/*antagonists & inhibitors
653 a MEDICINE
7001 a Fored, C Mu Karolinska Institutet4 aut
7001 a Brandt, Lu Karolinska Institutet4 aut
7001 a Baecklund, Evau Uppsala universitet,Reumatologi4 aut0 (Swepub:uu)evaba786
7001 a Bertilsson, L4 aut
7001 a Feltelius, Nu Medical Products Agency, Uppsala, Sweden4 aut0 (Swepub:uu)nifel021
7001 a Cöster, Lars,d 1945-u Östergötlands Läns Landsting,Linköpings universitet,Hälsouniversitetet,Reumatologi,Länskliniken för Reumatologi i Östergötland4 aut0 (Swepub:liu)larco79
7001 a Geborek, Pierreu Lund University,Lunds universitet,Reumatologi och molekylär skelettbiologi,Sektion III,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Rheumatology,Section III,Department of Clinical Sciences, Lund,Faculty of Medicine4 aut0 (Swepub:lu)reum-pge
7001 a Jacobsson, L T4 aut
7001 a Lindblad, Su Karolinska Institutet4 aut
7001 a Lysholm, J4 aut
7001 a Rantapää-Dahlqvist, Su Umeå universitet,Reumatologi4 aut0 (Swepub:umu)sora0001
7001 a Saxne, Toreu Lund University,Lunds universitet,Reumatologi och molekylär skelettbiologi,Sektion III,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Rheumatology,Section III,Department of Clinical Sciences, Lund,Faculty of Medicine4 aut0 (Swepub:lu)reum-tsa
7001 a Klareskog, Lu Karolinska Institutet4 aut
7102 a Karolinska Institutetb Reumatologi4 org
7730 t Annals of the Rheumatic Diseasesd : BMJg 64:10, s. 1421-1426q 64:10<1421-1426x 0003-4967x 1468-2060
8564 u http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Retrieve&list_uids=15829572&dopt=Citation
8564 u https://ard.bmj.com/content/64/10/1421.full.pdf
8564 u http://dx.doi.org/10.1136/ard.2004.033993x freey FULLTEXT
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-76846
8564 8u https://doi.org/10.1136/ard.2004.033993
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-13363
8564 8u https://lup.lub.lu.se/record/224681
8564 8u http://kipublications.ki.se/Default.aspx?queryparsed=id:1938210
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-33259

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