Right ectopic paraesophageal parathyroid adenoma with refractory hypercalcemia in pregnancy: A case report and review of the literature

Abusabeib, AbdelrahmanDepartment of General Surgery, Hamad General Hospital, Hamad Medical Corporation, Doha, Qatar (författare)

Right ectopic paraesophageal parathyroid adenoma with refractory hypercalcemia in pregnancy : A case report and review of the literature

CC BY-NC-ND 4.0
Introduction: Ectopic parathyroid adenoma is rare during pregnancy but poses multiple challenges in treatment. It presents as primary hyperparathyroidism which leads to symptoms and complications of hypercalcemia in both the mother and fetus. Presentation of case: A 38-year-old Sudanese female presented with diffuse bone pain and polyuria. Laboratory investigations revealed elevated serum calcium and parathyroid hormone. Ultrasound of the neck did not show any abnormal lesion, however 99mTc-sestamibi scan showed a right sided parathyroid adenoma, and an earlier CT scan showed the adenoma to be in an ectopic paraesophageal position. Focused surgical neck exploration was done, and the ectopic parathyroid adenoma was excised. Discussion: Preoperative localization of the ectopic parathyroid adenoma allows for a focused surgical procedure. Ultrasound is the safest during pregnancy, but 99mTc-sestamibi and CT scan may be necessary if ultrasound or initial bilateral neck exploration do not detect any adenoma. Mild elevations in maternal serum calcium can have detrimental effects on the fetus which suggests that a surgical approach may be necessary in the majority of cases. Conclusions: Ectopic parathyroid adenoma is rare during pregnancy and is detrimental to both the mother and fetus. Preoperative localization allows for a focused surgery which is a definitive treatment and can safely be performed during the 2nd trimester of pregnancy.

Bhat, HarunWeill Cornell Medicine in Qatar, Doha, Qatar (författare)
El Ansari, WalidHögskolan i Skövde,Institutionen för hälsovetenskaper,Forskningsmiljön hälsa, hållbarhet och digitalisering,Department of Surgery, Hamad General Hospital, Hamad Medical Corporation, Doha, Qatar / College of Medicine, Qatar University, Doha, Qatar,Individ och samhälle VIDSOC, Individual and Society(Swepub:his)alaw (författare)
Al Hassan, Mohamed S.Department of General Surgery, Hamad General Hospital, Hamad Medical Corporation, Doha, Qatar (författare)
Abdelaal, AbdelrahmanDepartment of General Surgery, Hamad General Hospital, Hamad Medical Corporation, Doha, Qatar (författare)
Department of General Surgery, Hamad General Hospital, Hamad Medical Corporation, Doha, QatarWeill Cornell Medicine in Qatar, Doha, Qatar (creator_code:org_t)

Ingår i:International Journal of Surgery Case Reports: Elsevier77, s. 229-2342210-2612

Av författaren/redakt...: Abusabeib, Abdel ...; Bhat, Harun; El Ansari, Walid; Al Hassan, Moham ...; Abdelaal, Abdelr ...

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