Sökning: WFRF:(Pasquier Philippe) > Genetic Association...
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008 | 230914s2023 | |||||||||||000 ||eng| | |
009 | oai:prod.swepub.kib.ki.se:153567997 | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-5116292 URI |
024 | 7 | a https://doi.org/10.1001/jamanetworkopen.2023.137342 DOI |
024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1535679972 URI |
040 | a (SwePub)uud (SwePub)ki | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Luo, Jiaou Copenhagen Univ Hosp, Dept Clin Biochem, Rigshosp, Copenhagen, Denmark.4 aut |
245 | 1 0 | a Genetic Associations Between Modifiable Risk Factors and Alzheimer Disease |
264 | 1 | b American Medical Association (AMA),c 2023 |
338 | a electronic2 rdacarrier | |
520 | a IMPORTANCE An estimated 40% of dementia is potentially preventable by modifying 12 risk factors throughout the life course. However, robust evidence for most of these risk factors is lacking. Effective interventions should target risk factors in the causal pathway to dementia.OBJECTIVE To comprehensively disentangle potentially causal aspects of modifiable risk factors for Alzheimer disease (AD) to inspire new drug targeting and improved prevention.DESIGN, SETTING, AND PARTICIPANTS This genetic association study was conducted using 2-sample univariable and multivariable mendelian randomization. Independent genetic variants associated with modifiable risk factors were selected as instrumental variables from genomic consortia. Outcome data for AD were obtained from the European Alzheimer & Dementia Biobank (EADB), generated on August 31, 2021. Main analyses were conducted using the EADB clinically diagnosed end point data. All analyses were performed between April 12 and October 27, 2022.EXPOSURES Genetically determined modifiable risk factors. MAIN OUTCOMES AND MEASURES Odds ratios (ORs) and 95% CIs for AD were calculated per 1-unit change of genetically determined risk factors.RESULTS The EADB-diagnosed cohort included 39106 participants with clinically diagnosed AD and 401577 control participants without AD. The mean age ranged from 72 to 83 years for participants with AD and 51 to 80 years for control participants. Among participants with AD, 54% to 75% were female, and among control participants, 48% to 60% were female. Genetically determined high-density lipoprotein (HDL) cholesterol concentrations were associated with increased odds of AD (OR per 1-SD increase, 1.10 [95% CI, 1.05-1.16]). Genetically determined high systolic blood pressure was associated with increased risk of AD after adjusting for diastolic blood pressure (OR per 10-mm Hg increase, 1.22 [95% CI, 1.02-1.46]). In a second analysis to minimize bias due to sample overlap, the entire UK Biobank was excluded from the EADB consortium; odds for AD were similar for HDL cholesterol (OR per 1-SD unit increase, 1.08 [95% CI, 1.02-1.15]) and systolic blood pressure after adjusting for diastolic blood pressure (OR per 10-mm Hg increase, 1.23 [95% CI, 1.01-1.50]).CONCLUSIONS AND RELEVANCE This genetic association study found novel genetic associations between high HDL cholesterol concentrations and high systolic blood pressure with higher risk of AD. These findings may inspire new drug targeting and improved prevention implementation. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kardiologi0 (SwePub)302062 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cardiac and Cardiovascular Systems0 (SwePub)302062 hsv//eng |
700 | 1 | a Thomassen, Jesper Qvistu Copenhagen Univ Hosp, Dept Clin Biochem, Rigshosp, Copenhagen, Denmark.4 aut |
700 | 1 | a Bellenguez, Celineu Univ Lille, Inst Pasteur Lille, INSERM, CHU Lille,Inst Pasteur Lille,U1167 RID Facteurs R, Lille, France.4 aut |
700 | 1 | a Grenier-Boley, Benjaminu Univ Lille, Inst Pasteur Lille, INSERM, CHU Lille,Inst Pasteur Lille,U1167 RID Facteurs R, Lille, France.4 aut |
700 | 1 | a de Rojas, Itziaru Univ Internac Catalunya, Inst Catala Neurociencies Aplicades, Res Ctr & Memory Clin Fundacio ACE, Barcelona, Spain.;Natl Inst Hlth Carlos III, Network Ctr Biomed Res Neurodegenerat Dis, Madrid, Spain.4 aut |
700 | 1 | a Castillo, Atahualpau Cardiff Univ, Sch Med, Div Psychol Med & Clin Neurosci, Cardiff, Wales.4 aut |
700 | 1 | a Parveen, Kayenatu Univ Cologne, Fac Med, Dept Psychiat & Psychotherapy, Div Neurogenet & Mol Psychiat, Cologne, Germany.;Univ Hosp Cologne, Univ Cologne, Cologne, Germany.;Univ Hosp Bonn, Fac Med, Dept Neurodegenerat Dis & Geriatr Psychiat, Bonn, Germany.4 aut |
700 | 1 | a Kuecuekali, Fahriu VIB Ctr Mol Neurol, Complex Genet Alzheimers Dis Grp, Antwerp, Belgium.;Univ Antwerp, Dept Biomed Sci, Antwerp, Belgium.4 aut |
700 | 1 | a Nicolas, Audeu Univ Lille, Inst Pasteur Lille, INSERM, CHU Lille,Inst Pasteur Lille,U1167 RID Facteurs R, Lille, France.4 aut |
700 | 1 | a Peters, Oliveru German Ctr Neurodegenerat Dis, Berlin, Germany.;Charite Univ med Berlin, Inst Psychiat & Psychotherapy, Berlin, Germany.;Free Univ Berlin, Humboldt Univ Berlin, Berlin, Germany.;Berlin Inst Hlth, Inst Psychiat & Psychotherapy, Berlin, Germany.4 aut |
700 | 1 | a Schneider, Anjau German Ctr Neurodegenerat Dis, Bonn, Germany.;Univ Hosp Bonn, Dept Neurodegenerat Dis & Geriatr Psychiat, Bonn, Germany.4 aut |
700 | 1 | a Dichgans, Martinu Ludwig Maximilians Univ Munchen, Univ Hosp, Inst Stroke & Dementia Res, Munich, Germany.;German Ctr Neurodegenerat Dis, Munich, Germany.;Munich Cluster Syst Neurol, Munich, Germany.4 aut |
700 | 1 | a Rujescu, Danu Med Univ Vienna, Dept Psychiat & Psychotherapy, Vienna, Austria.;Med Univ Vienna, Comprehens Ctr Clin Neurosci & Mental Hlth, Vienna, Austria.4 aut |
700 | 1 | a Scherbaum, Norbertu Univ Duisburg Essen, Fac Med, Dept Psychiat & Psychotherapy, LVR Hosp Essen, Essen, Germany.4 aut |
700 | 1 | a Juergen, Deckertu Univ Hosp Wurzburg, Dept Psychiat Psychosomat & Psychotherapy, Ctr Mental Hlth, Wurzburg, Germany.4 aut |
700 | 1 | a Riedel-Heller, Steffiu Univ Leipzig, Inst Social Med Occupat Hlth & Publ Hlth ISAP, Leipzig, Germany.4 aut |
700 | 1 | a Hausner, Lucreziau Heidelberg Univ, Fac Mannheim, Dept Geriatr Psychiat, Cent Inst Mental Hlth Mannheim, Heidelberg, Germany.4 aut |
700 | 1 | a Porcel, Laura Molinau Inst Investigaciones Biomed August Pi & Sunyer, Biobanc Hosp Clin, Neurol Tissue Bank, Barcelona, Spain.;Hosp Clin Barcelona, Dept Neurol, Alzheimers Dis & Other Cognit Disorders Unit, Barcelona, Spain.4 aut |
700 | 1 | a Duezel, Emrahu German Ctr Neurodegenerat Dis, Magdeburg, Germany.;Otto Von Guericke Univ, Inst Cognit Neurol & Dementia Res, Magdeburg, Germany.4 aut |
700 | 1 | a Grimmer, Timou Tech Univ Munich, Sch Med, Dept Psychiat & Psychotherapy, Klinikum Rechts Isar, Munich, Germany.4 aut |
700 | 1 | a Wiltfang, Jensu Univ Med Ctr Goettingen, Dept Psychiat & Psychotherapy, Gottingen, Germany.;German Ctr Neurodegenerat Dis, Gottingen, Germany.;Inst Biomed, Dept Med Sci, Aveiro, Portugal.4 aut |
700 | 1 | a Heilmann-Heimbach, Stefanieu Univ Bonn, Inst Human Genet, Sch Med, Bonn, Germany.;Univ Hosp Bonn, Bonn, Germany.4 aut |
700 | 1 | a Moebus, Susanneu Univ Duisburg Essen, Univ Hosp, Inst Urban Publ Hlth, Essen, Germany.4 aut |
700 | 1 | a Tegos, Thomasu Aristotle Univ Thessaloniki, Sch Med, Dept Neurol 1, Thessaloniki, Greece.4 aut |
700 | 1 | a Scarmeas, Nikolaosu Natl & Kapodistrian Univ Athens, Sch Med, Aiginit Hosp, Dept Neurol 1, Athens, Greece.;Columbia Univ, Taub Inst Res Alzheimers Dis & Aging Brain, Dept Neurol, Gertrude H Sergievsky Ctr, New York, NY USA.4 aut |
700 | 1 | a Clarimon, Jordiu Natl Inst Hlth Carlos III, Network Ctr Biomed Res Neurodegenerat Dis, Madrid, Spain.;Univ Autonoma Barcelona, Hosp Santa Creu & Sant Pau, Dept Neurol, II B Sant Pau, Barcelona, Spain.4 aut |
700 | 1 | a Moreno, Ferminu Natl Inst Hlth Carlos III, Network Ctr Biomed Res Neurodegenerat Dis, Madrid, Spain.;Hosp Univ Donostia, Dept Neurol, San Sebastian, Spain.;Inst Biodonostia, Neurosci Area, San Sebastian, Spain.4 aut |
700 | 1 | a Perez-Tur, Jordiu Natl Inst Hlth Carlos III, Network Ctr Biomed Res Neurodegenerat Dis, Madrid, Spain.;Inst Biomed Valencia, Unitat Genet Mol, Consejo Super Invest Cient, Valencia, Spain.;Inst Invest Sanit La Fe, Unidad Mixta Neurol Genet, Valencia, Spain.4 aut |
700 | 1 | a Bullido, Maria J.u Natl Inst Hlth Carlos III, Network Ctr Biomed Res Neurodegenerat Dis, Madrid, Spain.;UAM CSIC, Ctr Biol Mol Severo Ochoa, Madrid, Spain.;Inst Invest Sanit Hosp La Paz, Madrid, Spain.4 aut |
700 | 1 | a Pastor, Pauu Univ Hosp Germans Trias Pujol, Dept Neurol, Unit Neurodegenerat Dis, Barcelona, Spain.;Germans Trias Pujol Res Inst IGTP Badalona, Barcelona, Spain.4 aut |
700 | 1 | a Sanchez-Valle, Raquelu Univ Barcelona, Inst Investigac Biomed August Pi & Sunyer, Hosp Clin Barcelona, Alzheimers Dis & Other Cognit Disorders Unit,Serv, Barcelona, Spain.4 aut |
700 | 1 | a Alvarez, Victoriau Hosp Univ Cent Asturias, Lab Genet, Oviedo, Spain.;Inst Invest Sanit Principado Asturias, Asturias, Spain.4 aut |
700 | 1 | a Boada, Merceu Natl Inst Hlth Carlos III, Network Ctr Biomed Res Neurodegenerat Dis, Madrid, Spain.4 aut |
700 | 1 | a Garcia-Gonzalez, Pablou Univ Internac Catalunya, Inst Catala Neurociencies Aplicades, Res Ctr & Memory Clin Fundacio ACE, Barcelona, Spain.4 aut |
700 | 1 | a Puerta, Raquelu Univ Internac Catalunya, Inst Catala Neurociencies Aplicades, Res Ctr & Memory Clin Fundacio ACE, Barcelona, Spain.4 aut |
700 | 1 | a Mir, Pablou Natl Inst Hlth Carlos III, Network Ctr Biomed Res Neurodegenerat Dis, Madrid, Spain.;Univ Seville, Inst Biomed Sevilla, Hosp Univ Virgen Rocio,Consejo Super Invest Cient, Unidad Trastornos Movimiento,Serv Neurol & Neurof, Seville, Spain.4 aut |
700 | 1 | a Real, Luis M.u Hosp Univ Valme, Unidad Clin Enfermedades Infecc Microbiol, Seville, Spain.;Univ Malaga, Fac Med, Dept Especialidades Quirurg Bioquim & Inmunol, Malaga, Spain.4 aut |
700 | 1 | a Pinol-Ripoll, Gerardu Hosp Univ Santa Maria Lleida, Unitat Trastorns Cognitius, Lleida, Spain.;Inst Recerca Biomed Lleida, Lleida, Spain.4 aut |
700 | 1 | a Garcia-Alberca, Jose Mariau Natl Inst Hlth Carlos III, Network Ctr Biomed Res Neurodegenerat Dis, Madrid, Spain.;Inst Andaluz Neurociencia, Alzheimer Res Ctr Memory Clin, Malaga, Spain.4 aut |
700 | 1 | a Royo, Jose Luisu Univ Malaga, Fac Med, Dept Especialidades Quirurg Bioquim & Inmunol, Malaga, Spain.4 aut |
700 | 1 | a Rodriguez-Rodriguez, Eloyu Natl Inst Hlth Carlos III, Network Ctr Biomed Res Neurodegenerat Dis, Madrid, Spain.;Univ Cantabria, Marques Valdecilla Univ Hosp, Neurol Serv, Santander, Spain.;IDIVAL, Santander, Spain.4 aut |
700 | 1 | a Soininen, Hilkkau Univ Eastern Finland, Inst Clin Med, Neurol, Kuopio, Finland.4 aut |
700 | 1 | a Kuulasmaa, Teemuu Univ Eastern Finland, Inst Biomed, Kuopio, Finland.4 aut |
700 | 1 | a de Mendonca, Alexandreu Univ Lisbon, Fac Med, Lisbon, Portugal.4 aut |
700 | 1 | a Mehrabian, Shimau Med Univ Sofia, Neurol Clin, UH Alexandrovska, Sofia, Bulgaria.4 aut |
700 | 1 | a Hort, Jakubu Charles Univ Prague, Fac Med 2, Dept Neurol, Memory Clin, Prague, Czech Republic.;Motol Univ Hosp, Prague, Czech Republic.;St Annes Univ Hosp Brno, Int Clin Res Ctr, Brno, Czech Republic.4 aut |
700 | 1 | a Vyhnalek, Martinu Charles Univ Prague, Fac Med 2, Dept Neurol, Memory Clin, Prague, Czech Republic.;Motol Univ Hosp, Prague, Czech Republic.;St Annes Univ Hosp Brno, Int Clin Res Ctr, Brno, Czech Republic.4 aut |
700 | 1 | a van der Lee, Svenu St Annes Univ Hosp Brno, Int Clin Res Ctr, Brno, Czech Republic.;Vrije Univ Amsterdam, Genom Neurodegenerat Dis & Aging Human Genet, Amsterdam UMC, Locat VUmc, Amsterdam, Netherlands.;Vrije Univ Amsterdam, Alzheimer Ctr Amsterdam, Amsterdam UMC, Locat VUmc,Neurol, Amsterdam, Netherlands.;Amsterdam Neurosci Neurodegenerat, Amsterdam, Netherlands.4 aut |
700 | 1 | a Graff, Carolineu Karolinska Institutet4 aut |
700 | 1 | a Papenberg, Goranu Karolinska Inst, Dept Neurobiol Care Sci & Soc, Aging Res Ctr, Stockholm, Sweden.;Stockholm Univ, Stockholm, Sweden.4 aut |
700 | 1 | a Giedraitis, Vilmantasu Uppsala universitet,Geriatrik4 aut0 (Swepub:uu)vigie517 |
700 | 1 | a Boland, Anneu Univ Paris Saclay, Ctr Natl Rech Genom Humaine, CEA, Evry, France.4 aut |
700 | 1 | a Bacq-Daian, Delphineu Univ Paris Saclay, Ctr Natl Rech Genom Humaine, CEA, Evry, France.4 aut |
700 | 1 | a Deleuze, Jean-Francoisu Univ Paris Saclay, Ctr Natl Rech Genom Humaine, CEA, Evry, France.4 aut |
700 | 1 | a Nicolas, Gaelu Univ Rouen Normandie, Normandie Univ, Inserm U1245, Rouen, France.;CHU Rouen, Dept Genet, Rouen, France.;Ctr Natl Reference Malades Alzheimer Jeunes, Rouen, France.4 aut |
700 | 1 | a Dufouil, Caroleu Univ Bordeaux, Bordeaux Populat Hlth Res Ctr, INSERM, UMR 1219,ISPED,CIC 1401 EC, Bordeaux, France.;CHU Bordeaux, Pole Sante Publ, Bordeaux, France.4 aut |
700 | 1 | a Pasquier, Florenceu Univ Lille, CHU Lille, INSERM, Resources & Res Memory Ctr Distalz,UMR1172, Lille, France.4 aut |
700 | 1 | a Hanon, Olivieru Univ Paris, EA 4468, Hop Broca, Assistance Publ Hop Paris, Paris, France.4 aut |
700 | 1 | a Debette, Stephanieu Univ Bordeaux, Bordeaux Populat Hlth Res Ctr, INSERM, Bordeaux, France.;Bordeaux Univ Hosp, Dept Neurol, Bordeaux, France.4 aut |
700 | 1 | a Gruenblatt, Ednau Univ Zurich, Psychiat Univ Hosp Zurich, Dept Child & Adolescent Psychiat & Psychotherapy, Zurich, Switzerland.;Univ Zurich, Neuroscience Ctr Zurich, Zurich, Switzerland.;Swiss Fed Inst Technol, Zurich, Switzerland.;Univ Zurich, Zurich Ctr Integrat Human Physiol, Zurich, Switzerland.4 aut |
700 | 1 | a Popp, Juliusu Univ Lausanne Hosp, Dept Psychiat, Old Age Psychiat, Lausanne, Switzerland.;Univ Hosp Psychiat Zurich, Dept Geriatr Psychiat, Zurich, Switzerland.;Univ Zurich, Dept Psychiat Psychotherapy & Psychosomat, Zurich, Switzerland.4 aut |
700 | 1 | a Benussi, Luisau IRCCS Ist Ctr San Giovanni Dio Fatebenefratelli, Mol Markers Lab, Brescia, Italy.4 aut |
700 | 1 | a Galimberti, Danielau Osped Policlin, Fdn IRCCS Ca Granda, Neurodegenerat Dis Unit, Milan, Italy.;Univ Milan, Dept Biomed Surg & Dent Sci, Milan, Italy.4 aut |
700 | 1 | a Arosio, Beatriceu Univ Milan, Dept Clin Sci & Commun Hlth, Milan, Italy.;Fdn IRCCS Ca Granda Osped Maggiore Policli, Geriatr Unit, Milan, Italy.4 aut |
700 | 1 | a Mecocci, Patriziau Univ Perugia, Inst Gerontol & Geriatr, Dept Med & Surg, Perugia, Italy.;Karolinska Inst, Dept Neurobiol Care Sci & Soc, Div Clin Geriatr, Stockholm, Sweden.4 aut |
700 | 1 | a Solfrizzi, Vincenzou Univ Bari Aldo Moro, Interdisciplinary Dept Med, Geriatr Med & Memory Unit, Bari, Italy.4 aut |
700 | 1 | a Parnetti, Lucillau Univ Perugia, Neurol Sect, Lab Clin Neurochem, Ctr Memory Disturbances, Perugia, Italy.4 aut |
700 | 1 | a Squassina, Alessiou Univ Cagliari, Dept Biomed Sci, Sect Neurosci & Clin Pharmacol, Cagliari, Italy.4 aut |
700 | 1 | a Tremolizzo, Luciou Hosp San Gerardo, Neurol Unit, Monza, Italy.;Univ Milano Bicocca, Milan, Italy.4 aut |
700 | 1 | a Borroni, Barbarau Univ Brescia, Ctr Neurodegenerat Disorders, Neurol Unit, Dept Clin & Expt Sci, Brescia, Italy.4 aut |
700 | 1 | a Nacmias, Benedettau Univ Florence, Dept Neurosci Psychol Drug Res & Child Hlth, Florence, Italy.;IRCCS Fdn Don Carlo Gnocchi, Florence, Italy.4 aut |
700 | 1 | a Sorbi, Sandrou Univ Florence, Dept Neurosci Psychol Drug Res & Child Hlth, Florence, Italy.;IRCCS Fdn Don Carlo Gnocchi, Florence, Italy.4 aut |
700 | 1 | a Caffarra, Paolou Univ Parma, Neurol Unit, Parma, Italy.4 aut |
700 | 1 | a Seripa, Davideu Vito Fazzi Hosp, Dept Hematol & Stem Cell Transplant, Lab Adv Hematol Diagnost, Lecce, Italy.4 aut |
700 | 1 | a Rainero, Innocenzou Univ Torino, Dept Neurosci Rita Levi Montalcini, Turin, Italy.4 aut |
700 | 1 | a Daniele, Antoniou Univ Cattolica Sacro Cuore, Dept Neurosci, Rome, Italy.;IRCCS Fdn Policlin Univ A Gemelli, Neurol Unit, Rome, Italy.4 aut |
700 | 1 | a Masullo, Carlou Univ Cattolica Sacro Cuore, Inst Neurol, Rome, Italy.4 aut |
700 | 1 | a Spalletta, Gianfrancou IRCCS Santa Lucia Fdn, Lab Neuropsychiat, Rome, Italy.;Baylor Coll Med, Dept Psychiat & Behav Sci, Houston, TX USA.4 aut |
700 | 1 | a Williams, Julieu Cardiff Univ, Sch Med, UK Dementia Res Inst Cardiff, Cardiff, Wales.4 aut |
700 | 1 | a Amouyel, Philippeu Univ Lille, Inst Pasteur Lille, INSERM, CHU Lille,Inst Pasteur Lille,U1167 RID Facteurs R, Lille, France.4 aut |
700 | 1 | a Jessen, Franku Univ Cologne, Fac Med, Dept Psychiat & Psychotherapy, Div Neurogenet & Mol Psychiat, Cologne, Germany.;Univ Hosp Cologne, Univ Cologne, Cologne, Germany.;German Ctr Neurodegenerat Dis, Bonn, Germany.;Univ Cologne, Cluster Excellence Cellular Stress Responses Agin, Cologne, Germany.4 aut |
700 | 1 | a Kehoe, Patricku Univ Bristol, Bristol Med Sch, Translat Hlth Sci, Bristol, England.4 aut |
700 | 1 | a Magda, Tsolakiu Aristotle Univ Thessaloniki, Sch Med, Dept Neurol 1, Thessaloniki, Greece.;Alzheimer Hellas, Thessaloniki, Greece.4 aut |
700 | 1 | a Rossi, Giacominau Fdn IRCCS Ist Neurol Carlo Besta, Unit Neurol Neuropathol, Milan, Italy.4 aut |
700 | 1 | a Sanchez-Juan, Pascualu Natl Inst Hlth Carlos III, Network Ctr Biomed Res Neurodegenerat Dis, Madrid, Spain.;Alzheimers Ctr Reina Sofia CIEN Fdn ISCIII, Madrid, Spain.4 aut |
700 | 1 | a Sleegers, Kristelu VIB Ctr Mol Neurol, Complex Genet Alzheimers Dis Grp, Antwerp, Belgium.;Univ Antwerp, Dept Biomed Sci, Antwerp, Belgium.4 aut |
700 | 1 | a Ingelsson, Martinu Karolinska Univ Hosp Solna, Unit Hereditary Dementias Theme Aging, Stockholm, Sweden.;Univ Hlth Network, Krembil Brain Inst, Toronto, ON, Canada.;Univ Toronto, Dept Med, Toronto, ON, Canada.;Univ Toronto, Tanz Ctr Res Neurodegenerat Dis, Toronto, ON, Canada.4 aut |
700 | 1 | a Andreassen, Ole A.u Oslo Univ Hosp, Div Mental Hlth & Addict, NORMENT Ctr, Oslo, Norway.;Univ Oslo, Inst Clin Med, Oslo, Norway.4 aut |
700 | 1 | a Hiltunen, Mikkou Univ Cantabria, Marques Valdecilla Univ Hosp, Neurol Serv, Santander, Spain.;IDIVAL, Santander, Spain.4 aut |
700 | 1 | a Van Duijn, Corneliau Erasmus MC, Dept Epidemiol, Rotterdam, Netherlands.;Univ Oxford, Nuffield Dept Populat Hlth, Oxford, England.4 aut |
700 | 1 | a Sims, Rebeccau Cardiff Univ, Sch Med, Div Psychol Med & Clin Neurosci, Cardiff, Wales.4 aut |
700 | 1 | a van der Flier, Wiesje4 aut |
700 | 1 | a Ruiz, Agustinu Univ Internac Catalunya, Inst Catala Neurociencies Aplicades, Res Ctr & Memory Clin Fundacio ACE, Barcelona, Spain.;Natl Inst Hlth Carlos III, Network Ctr Biomed Res Neurodegenerat Dis, Madrid, Spain.4 aut |
700 | 1 | a Ramirez, Alfredou Univ Cologne, Fac Med, Dept Psychiat & Psychotherapy, Div Neurogenet & Mol Psychiat, Cologne, Germany.;Univ Hosp Cologne, Univ Cologne, Cologne, Germany.;Univ Hosp Bonn, Fac Med, Dept Neurodegenerat Dis & Geriatr Psychiat, Bonn, Germany.;German Ctr Neurodegenerat Dis, Bonn, Germany.;Univ Cologne, Cluster Excellence Cellular Stress Responses Agin, Cologne, Germany.;Glenn Biggs Inst Alzheimers & Neurodegenerat Dis, Dept Psychiat, San Antonio, TX USA.;Glenn Biggs Inst Alzheimers & Neurodegenerat Dis, San Antonio, TX USA.4 aut |
700 | 1 | a Lambert, Jean-Charlesu Univ Lille, Inst Pasteur Lille, INSERM, CHU Lille,Inst Pasteur Lille,U1167 RID Facteurs R, Lille, France.4 aut |
700 | 1 | a Frikke-Schmidt, Ruthu Copenhagen Univ Hosp, Dept Clin Biochem, Rigshosp, Copenhagen, Denmark.;Univ Copenhagen, Dept Clin Med, Copenhagen, Denmark.4 aut |
710 | 2 | a Copenhagen Univ Hosp, Dept Clin Biochem, Rigshosp, Copenhagen, Denmark.b Univ Lille, Inst Pasteur Lille, INSERM, CHU Lille,Inst Pasteur Lille,U1167 RID Facteurs R, Lille, France.4 org |
773 | 0 | t JAMA Network Opend : American Medical Association (AMA)g 6:5q 6:5x 2574-3805 |
856 | 4 | u https://doi.org/10.1001/jamanetworkopen.2023.13734y Fulltext |
856 | 4 | u https://uu.diva-portal.org/smash/get/diva2:1797262/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-511629 |
856 | 4 8 | u https://doi.org/10.1001/jamanetworkopen.2023.13734 |
856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:153567997 |
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