Sökning: WFRF:(Timmerman D.) > Clinical and ultras...
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000 | 05407naa a2200517 4500 | |
001 | oai:lup.lub.lu.se:d69d1cfe-f7a2-4d47-a6f2-fa41d21fa5a2 | |
003 | SwePub | |
008 | 171122s2017 | |||||||||||000 ||eng| | |
024 | 7 | a https://lup.lub.lu.se/record/d69d1cfe-f7a2-4d47-a6f2-fa41d21fa5a22 URI |
024 | 7 | a https://doi.org/10.1002/uog.173922 DOI |
040 | a (SwePub)lu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a art2 swepub-publicationtype |
072 | 7 | a ref2 swepub-contenttype |
100 | 1 | a Di Legge, A.u Catholic University of the Sacred Heart, Rome4 aut |
245 | 1 0 | a Clinical and ultrasound characteristics of surgically removed adnexal lesions with largest diameter ≤ 2.5 cm : a pictorial essay |
264 | c 2017-11-05 | |
264 | 1 | b Wiley,c 2017 |
300 | a 9 s. | |
520 | a Objectives: To describe the ultrasound characteristics, indications for surgery and histological diagnoses of surgically removed adnexal masses with a largest diameter of ≤ 2.5 cm (very small tumors), to estimate the sensitivity and specificity of diagnosis of malignancy by subjective assessment of ultrasound images of very small tumors and to present a collection of ultrasound images of surgically removed very small tumors, with emphasis on those causing diagnostic difficulty. Methods: Information on surgically removed adnexal tumors with a largest diameter of ≤ 2.5 cm was retrieved from the ultrasound databases of seven participating centers. The ultrasound images were described using the International Ovarian Tumor Analysis terminology. The original diagnosis, based on subjective assessment of the ultrasound images by the ultrasound examiner, was used to calculate the sensitivity and specificity of diagnosis of malignancy. Results: Of the 129 identified adnexal masses with largest diameter ≤ 2.5 cm, 104 (81%) were benign, 15 (12%) borderline malignant and 10 (8%) invasive tumors. The main indication for performing surgery was suspicion of malignancy in 22% (23/104) of the benign tumors and in all 25 malignant tumors. None of the malignant tumors was a unilocular cyst (vs 50% of the benign tumors), all malignancies contained solid components (vs 43% of the benign tumors), 80% of the borderline tumors had papillary projections (vs 21% of the benign tumors and 20% of the invasive malignancies) and all invasive tumors and 80% of the borderline tumors were vascularized on color/power Doppler examination (vs 44% of the benign tumors). The ovarian crescent sign was present in 85% of the benign tumors, 80% of the borderline tumors and 50% of the invasive malignancies. The sensitivity of diagnosis of malignancy by subjective assessment of ultrasound images was 100% (25/25) and the specificity was 86% (89/104). Excluding unilocular cysts, the specificity was 71% (37/52). Analysis of images illustrated the difficulty in distinguishing benign from borderline very small cysts with papillations and benign from malignant very small well vascularized (color score 3 or 4) solid adnexal tumors. Conclusions: Very small malignant tumors manifest generally accepted ultrasound signs of malignancy. Small unilocular cysts are usually benign, while small non-unilocular masses, particularly ones with solid components, incur a risk of malignancy and pose a clinical dilemma. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Radiologi och bildbehandling0 (SwePub)302082 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Radiology, Nuclear Medicine and Medical Imaging0 (SwePub)302082 hsv//eng |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Reproduktionsmedicin och gynekologi0 (SwePub)302202 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Obstetrics, Gynaecology and Reproductive Medicine0 (SwePub)302202 hsv//eng |
653 | a adnexal lesion | |
653 | a Doppler | |
653 | a ovarian neoplasm | |
653 | a ultrasonography | |
700 | 1 | a Pollastri, P.u Istituti Ospitalieri di Cremona4 aut |
700 | 1 | a Mancari, R.u European Institute of Oncology4 aut |
700 | 1 | a Ludovisi, M.u University College London4 aut |
700 | 1 | a Mascilini, F.u Catholic University of the Sacred Heart, Rome4 aut |
700 | 1 | a Franchi, D.u European Institute of Oncology4 aut |
700 | 1 | a Jurkovic, D.u University College London4 aut |
700 | 1 | a Coccia, M. E.u University of Florence4 aut |
700 | 1 | a Timmerman, D.u Catholic University of Leuven4 aut |
700 | 1 | a Scambia, G.u Catholic University of the Sacred Heart, Rome4 aut |
700 | 1 | a Testa, A.u Catholic University of the Sacred Heart, Rome4 aut |
700 | 1 | a Valentin, L.u Lund University,Lunds universitet,Obstetrisk, gynekologisk och prenatal ultraljudsdiagnostik,Forskargrupper vid Lunds universitet,Obstetric, Gynaecological and Prenatal Ultrasound Research,Lund University Research Groups,Skåne University Hospital4 aut0 (Swepub:lu)obst-lva |
710 | 2 | a Catholic University of the Sacred Heart, Romeb Istituti Ospitalieri di Cremona4 org |
773 | 0 | t Ultrasound in Obstetrics and Gynecologyd : Wileyg 50:5, s. 648-656q 50:5<648-656x 0960-7692 |
856 | 4 | u http://dx.doi.org/10.1002/uog.17392x freey FULLTEXT |
856 | 4 | u https://obgyn.onlinelibrary.wiley.com/doi/pdfdirect/10.1002/uog.17392 |
856 | 4 8 | u https://lup.lub.lu.se/record/d69d1cfe-f7a2-4d47-a6f2-fa41d21fa5a2 |
856 | 4 8 | u https://doi.org/10.1002/uog.17392 |
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