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Sökning: WFRF:(Utheim Tor P.) > The use of in vivo ...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00003479naa a2200397 4500
001oai:DiVA.org:liu-186845
003SwePub
008220706s2022 | |||||||||||000 ||eng|
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-1868452 URI
0247 a https://doi.org/10.1016/j.jtos.2022.03.0022 DOI
040 a (SwePub)liu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Bakken, Ingvild M.u Sorlandet Hosp Arendal, Norway4 aut
2451 0a The use of in vivo confocal microscopy in fungal keratitis - Progress and challenges
264 1b Elsevier,c 2022
338 a electronic2 rdacarrier
520 a Fungal keratitis (FK) is a serious and sight-threatening corneal infection with global reach. The need for prompt diagnosis is paramount, as a delay in initiation of treatment could lead to irreversible vision loss. Current "gold standard" diagnostic methods, namely corneal smear and culture, have limitations due to diagnostic insensitivity and their time-consuming nature. PCR is a newer, complementary method used in the diagnosis of fungal keratitis, whose results are also sample-dependent. In vivo confocal microscopy (IVCM) is a promising complementary diagnostic method of increasing importance as it allows non-invasive real-time direct visualization of potential fungal pathogens and manifesting infection directly in the patients cornea. In numerous articles and case reports, FK diagnosis by IVCM has been evaluated, and different features, approaches, sensitivity/specificity, and limitations have been noted. Here, we provide an up-to-date, comprehensive review of the current literature and present the authors combined recommendations for fungal identification in IVCM images, while also looking to the future of FK assessment by IVCM using artificial intelligence methods.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Radiologi och bildbehandling0 (SwePub)302082 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Radiology, Nuclear Medicine and Medical Imaging0 (SwePub)302082 hsv//eng
653 a Fungal keratitis; Cornea; Diagnostics; In vivo confocal microscopy; Artificial intelligence
7001 a Jackson, Catherine J.u Ifocus Eye Clin, Norway; Univ Oslo, Norway4 aut
7001 a Utheim, Tor P.u Sorlandet Hosp Arendal, Norway; Oslo Univ Hosp, Norway; Univ Agder, Norway4 aut
7001 a Villani, Edoardou Univ Milan, Italy; San Giuseppe Hosp, Italy4 aut
7001 a Hamrah, Pedramu Tufts Univ, MA 02111 USA4 aut
7001 a Kheirkhah, Ahmadu UT Hlth San Antonio, TX USA4 aut
7001 a Nielsen, Esbenu Aarhus Univ Hosp, Denmark4 aut
7001 a Hau, Scottu Moorfields Eye Hosp NHS Fdn Trust, England; UCL Inst Ophthalmol, England4 aut
7001 a Lagali, Neilu Linköpings universitet,Avdelningen för sinnesorgan och kommunikation,Medicinska fakulteten,Region Östergötland, Ögonkliniken US,Sorlandet Hosp Arendal, Norway4 aut0 (Swepub:liu)neina50
7102 a Sorlandet Hosp Arendal, Norwayb Ifocus Eye Clin, Norway; Univ Oslo, Norway4 org
7730 t Ocular Surfaced : Elsevierg 24, s. 103-118q 24<103-118x 1542-0124
8564 u https://liu.diva-portal.org/smash/get/diva2:1681192/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-186845
8564 8u https://doi.org/10.1016/j.jtos.2022.03.002

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