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Diagnosis and treat...
Diagnosis and treatment of chronic constipation--a European perspective.
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Tack, J (författare)
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Müller-Lissner, S (författare)
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Stanghellini, V (författare)
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Boeckxstaens, G (författare)
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Kamm, M A (författare)
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- Simrén, Magnus, 1966 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för invärtesmedicin,Centrum för personcentrerad vård vid Göteborgs universitet (GPCC),Institute of Medicine, Department of Internal Medicine,University of Gothenburg Centre for person-centred care (GPCC)
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Galmiche, J-P (författare)
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Fried, M (författare)
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(creator_code:org_t)
- 2011-05-24
- 2011
- Engelska.
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Ingår i: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. - : Wiley. - 1365-2982. ; 23:8, s. 697-710
- Relaterad länk:
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https://onlinelibrar...
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https://gup.ub.gu.se...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- BACKGROUND: Although constipation can be a chronic and severe problem, it is largely treated empirically. Evidence for the efficacy of some of the older laxatives from well-designed trials is limited. Patients often report high levels of dissatisfaction with their treatment, which is attributed to a lack of efficacy or unpleasant side-effects. Management guidelines and recommendations are limited and are not sufficiently current to include treatments that became available more recently, such as prokinetic agents in Europe. PURPOSE: We present an overview of the pathophysiology, diagnosis, current management and available guidelines for the treatment of chronic constipation, and include recent data on the efficacy and potential clinical use of the more newly available therapeutic agents. Based on published algorithms and guidelines on the management of chronic constipation, secondary pathologies and causes are first excluded and then diet, lifestyle, and, if available, behavioral measures adopted. If these fail, bulk-forming, osmotic, and stimulant laxatives can be used. If symptoms are not satisfactorily resolved, a prokinetic agent such as prucalopride can be prescribed. Biofeedback is recommended as a treatment for chronic constipation in patients with disordered defecation. Surgery should only be considered once all other treatment options have been exhausted.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Gastroenterologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Gastroenterology and Hepatology (hsv//eng)
Nyckelord
- Chronic Disease
- Clinical Trials as Topic
- Constipation
- diagnosis
- drug therapy
- physiopathology
- Defecation
- drug effects
- Europe
- Gastrointestinal Agents
- pharmacology
- therapeutic use
- Gastrointestinal Transit
- physiology
- Guidelines as Topic
- Humans
- Laxatives
- pharmacology
- therapeutic use
- Patient Satisfaction
Publikations- och innehållstyp
- ref (ämneskategori)
- for (ämneskategori)
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