Validation of the Health Assessment Tool (HAT) based on four aging cohorts from the Swedish National study on Aging and Care

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Validation of the Health Assessment Tool (HAT) based on four aging cohorts from the Swedish National study on Aging and Care

Abbadi, Ahmad (författare): Karolinska Institutet, Sweden;Stockholm University, Sweden

Kokoroskos, Emmanouil (författare): Karolinska Institutet, Sweden;Stockholm University, Sweden;Lideta Mälardalen AB, Sweden

Stamets, Matthew (författare): Karolinska Institutet, Sweden;Stockholm University, Sweden

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Vetrano, Davide L. (författare): Karolinska Institutet, Sweden;Stockholm University, Sweden;Stockholm Gerontology Research Center, Sweden

Orsini, Nicola (författare): Karolinska Institutet, Sweden

Elmståhl, Sölve (författare): Lund University, Sweden

Fagerström, Cecilia, Professor, 1973- (författare): Linnéuniversitetet,Institutionen för hälso- och vårdvetenskap (HV),Region Kalmar, Sweden

Wimo, Anders (författare): Karolinska Institutet, Sweden

Sköldunger, Anders (författare): Karolinska Institutet, Sweden

Sanmartin Berglund, Johan, Professor (författare): Blekinge Tekniska Högskola,Institutionen för hälsa,Blekinge Institute of Technology, Sweden

Olsson, Christina B. (författare): Karolinska Institutet, Sweden;Region Stockholm, Sweden

Wachtler, Caroline (författare): Karolinska Institutet, Sweden;Region Stockholm, Sweden

Fratiglioni, Laura (författare): Karolinska Institutet, Sweden;Stockholm University, Sweden;Stockholm Gerontology Research Center, Sweden

Calderón-Larrañaga, Amaia (författare): Karolinska Institutet, Sweden;Stockholm University, Sweden;Stockholm Gerontology Research Center, Sweden

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BioMed Central (BMC), 2024
2024
Engelska.
Ingår i: BMC Medicine. - : BioMed Central (BMC). - 1741-7015. ; 22:1

Relaterad länk:: https://doi.org/10.1...; visa fler...; https://bth.diva-por... (primary) (Raw object); https://urn.kb.se/re...; https://doi.org/10.1...; https://urn.kb.se/re...; visa färre...

Tidskriftsartikel (refereegranskat)

Abstract Ämnesord

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Background: As global aging accelerates, routinely assessing the functional status and morbidity burden of older patients becomes paramount. The aim of this study is to assess the validity of the comprehensive clinical and functional Health Assessment Tool (HAT) based on four cohorts of older adults (60 + years) from the Swedish National study on Aging and Care (SNAC) spanning urban, suburban, and rural areas.Methods: The HAT integrates five health indicators (gait speed, global cognition, number of chronic diseases, and basic and instrumental activities of daily living), providing an individual-level score between 0 and 10. The tool was constructed using nominal response models, first separately for each cohort and then in a harmonized dataset. Outcomes included all-cause mortality over a maximum follow-up of 16 years and unplanned hospital admissions over a maximum of 3 years of follow-up. The predictive capacity was assessed through the area under the curve (AUC) using logistic regressions. For time to death, Cox regressions were performed, and Harrell’s C-indices were reported. Results from the four cohorts were pooled using individual participant data meta-analysis and compared with those from the harmonized dataset.Results: The HAT demonstrated high predictive capacity across all cohorts as well as in the harmonized dataset. In the harmonized dataset, the AUC was 0.84 (95% CI 0.81–0.87) for 1-year mortality, 0.81 (95% CI 0.80–0.83) for 3-year mortality, 0.80 (95% CI 0.79–0.82) for 5-year mortality, 0.69 (95% CI 0.67–0.70) for 1-year unplanned admissions, and 0.69 (95% CI 0.68–0.70) for 3-year unplanned admissions. The Harrell’s C for time-to-death throughout 16 years of follow-up was 0.75 (95% CI 0.74–0.75).Conclusions: The HAT is a highly predictive, clinically intuitive, and externally valid instrument with potential for better addressing older adults’ health needs and optimizing risk stratification at the population level. © The Author(s) 2024.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Geriatrik (hsv//swe)
MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Geriatrics (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Omvårdnad (hsv//swe)
MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Nursing (hsv//eng)

Nyckelord

Aging cohorts
External validation
Frailty
Geriatric health assessment
Activities of Daily Living
Aged
Aged
80 and over
Aging
Chronic Disease
Cohort Studies
Female
Geriatric Assessment
Humans
Male
Middle Aged
Sweden
adult
all cause mortality
area under the curve
Article
cognition
daily life activity
follow up
gait
health care
hospital admission
hospitalization
human
major clinical study
Mini Mental State Examination
mortality
nurse
nurse practitioner
proportional hazards model
psychologist
quality of life
questionnaire
time series analysis
validation study
waist circumference
cohort analysis
epidemiology
procedures
very elderly
Omvårdnad

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Av författaren/redakt...: Abbadi, Ahmad; Kokoroskos, Emma ...; Stamets, Matthew; Vetrano, Davide ...; Orsini, Nicola; Elmståhl, Sölve; visa fler...; Fagerström, Ceci ...; Wimo, Anders; Sköldunger, Ande ...; Sanmartin Berglu ...; Olsson, Christin ...; Wachtler, Caroli ...; Fratiglioni, Lau ...; Calderón-Larraña ...; visa färre...

Om ämnet

MEDICIN OCH HÄLSOVETENSKAP: MEDICIN OCH HÄLS ...; och Klinisk medicin; och Geriatrik

MEDICIN OCH HÄLSOVETENSKAP: MEDICIN OCH HÄLS ...; och Hälsovetenskap; och Omvårdnad

Artiklar i publikationen: BMC Medicine

Av lärosätet: Blekinge Tekniska Högskola; Linnéuniversitetet

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