WFRF:(Bloem Bastiaan R.)
Search: WFRF:(Bloem Bastiaan R.) > Factors associated ...
- 12 of 16
- Previous record
- Next record
- To hitlist
Factors associated with self-rated health in people with late-stage parkinson’s and cognitive impairment
-
- Pigott, Jennifer S. (author)
- University College London
-
- Armstrong, Megan (author)
- Queen Mary University,University College London
-
- Davies, Nathan (author)
- University College London
- show more...
- show less...
- (creator_code:org_t)
- 2024
- 2024
- English.
- In: Quality of Life Research. - 0962-9343.
- Journal article (peer-reviewed)
Abstract
Subject headings
Close
- Purpose: To investigate the contributors to self-rated health in people with late-stage Parkinson’s disease (PD) and cognitive impairment. Methods: A secondary analysis of baseline data from the international Care of Late-Stage Parkinsonism (CLaSP) cohort study was conducted. Participants with PD and either dementia or mild cognitive impairment or MMSE < 24/30 in the absence of major depression were included if they had completed the EQ-5D-3L assessment (n = 277). Factors associated with self-rated health (EQ-5D-3L Index and Visual Analogue Scale) were investigated through multivariable linear regression. Results: More severe PD (motor and non-motor) was associated with worse self-rated health. The EQ-5D-3L dimensions of Mobility, Self-Care and Usual Activities were almost universally affected; the latter two particularly severely. Being unable to perform usual activities or having moderate to extreme anxiety or depression were significantly associated with EQ-5D-3L Visual Analogue Scale, suggesting these are particularly valued. Worse motor impairment and function and the non-motor symptom domains of mood, perception, sexual function, and miscellaneous (e.g., pain) were associated with worse self-rated health, whereas greater burden of gastrointestinal symptoms was associated with better self-rated health in multivariate analysis. Better self-rated health was associated with recent PD nurse consultation, and higher doses of dopaminergic medication. Conclusion: Improvement of activities of daily living, mood and anxiety should be prioritised in clinical practice, with consideration of perception and sexual function in this population. Recent nurse consultations and higher antiparkinsonian doses are associated with better self-rated health, suggesting there is no room for a therapeutic nihilism in this population of people within a complex phase of PD.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Neurologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Neurology (hsv//eng)
Keyword
- Cognitive impairment
- Parkinson’s disease
- Parkinson’s disease dementia
- Self-rated health
Publication and Content Type
- art (subject category)
- ref (subject category)
Find in a library
- Quality of Life Research (Search for host publication in LIBRIS)
To the university's database
- 12 of 16
- Previous record
- Next record
- To hitlist
Find more in SwePub
- By the author/editor
- Pigott, Jennifer ...
- Armstrong, Megan
- Davies, Nathan
- Davis, Daniel
- Bloem, Bastiaan ...
- Lorenzl, Stefan
- show more...
- Meissner, Wassil ...
- Odin, Per
- Ferreira, Joaqui ...
- Dodel, Richard
- Schrag, Anette
- show less...
- About the subject
-
- MEDICAL AND HEALTH SCIENCES
- MEDICAL AND HEAL ...
- and Clinical Medicin ...
- and Neurology
- Articles in the publication
- Quality of Life ...
- By the university
- Lund University
Search outside SwePub
- Extend your search to:
- Google Book Search
- Google Scholar
Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.
- Copyright © LIBRIS - National Library Systems
- LIBRIS.kb.se
