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Sökning: WFRF:(Boge Lukas) > Lipid-based nanofor...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00003095naa a2200445 4500
001oai:DiVA.org:ri-90
003SwePub
008160428s2016 | |||||||||||000 ||eng|
024a https://urn.kb.se/resolve?urn=urn:nbn:se:ri:diva-902 URI
024a https://doi.org/10.1016/j.ijpharm.2016.02.0192 DOI
040 a (SwePub)ri
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a for2 swepub-publicationtype
100a Matougui, Nadau Inserm, France4 aut
2451 0a Lipid-based nanoformulations for peptide delivery
264 1b Elsevier,c 2016
338 a print2 rdacarrier
520 a Nanoformulations have attracted a lot of attention because of their size-dependent properties. Among the array of nanoformulations, lipid nanoformulations (LNFs) have evoked increasing interest because of the advantages of their high degree of biocompatibility and versatility. The performance of lipid nanoformulations is greatly influenced by their composition and structure. Therapeutic peptides represent a growing share of the pharmaceutical market. However, the main challenge for their development into commercial products is their inherent physicochemical and biological instability. Important peptides such as insulin, calcitonin and cyclosporin A have been incorporated into LNFs. The association or encapsulation of peptides within lipid-based carriers has shown to protect the labile molecules against enzymatic degradation. This review describes strategies used for the formulation of peptides and some methods used for the assessment of association efficiency. The advantages and drawbacks of such carriers are also described.
650 7a NATURVETENSKAPx Kemix Annan kemi0 (SwePub)104992 hsv//swe
650 7a NATURAL SCIENCESx Chemical Sciencesx Other Chemistry Topics0 (SwePub)104992 hsv//eng
650 7a NATURVETENSKAPx Kemix Fysikalisk kemi0 (SwePub)104022 hsv//swe
650 7a NATURAL SCIENCESx Chemical Sciencesx Physical Chemistry0 (SwePub)104022 hsv//eng
650 7a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Farmaceutiska vetenskaper0 (SwePub)301012 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Pharmaceutical Sciences0 (SwePub)301012 hsv//eng
653 a Drug delivery
653 a Lipids
653 a Nanoformulations
653 a Peptides
700a Boge, Lukasu RISE,Life Science4 aut0 (Swepub:ri)lukas.boge@ri.se
700a Groo, Anne-Claireu Inserm, France4 aut
700a Umerska, Anitau Inserm, France4 aut
700a Ringstad, Lovisau RISE,Life Science4 aut
700a Bysell, Helenau RISE,Life Science4 aut0 (Swepub:ri)helena.bysell@ri.se
700a Saulnier, Patricku Inserm, France; CHU Angers, France4 aut
710a Inserm, Franceb Life Science4 org
773t International Journal of Pharmaceuticsd : Elsevierg 502:1-2, s. 80-97q 502:1-2<80-97x 0378-5173x 1873-3476
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:ri:diva-90
8564 8u https://doi.org/10.1016/j.ijpharm.2016.02.019

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