WFRF:(Poirier P.)
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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 05093naa a2200829 4500 | |
| 001 | oai:gup.ub.gu.se/307049 | |
| 003 | SwePub | |
| 008 | 240528s2021 | |||||||||||000 ||eng| | |
| 024 | 7 | a https://gup.ub.gu.se/publication/3070492 URI |
| 024 | 7 | a https://doi.org/10.1136/bmj.n15542 DOI |
| 040 | a (SwePub)gu | |
| 041 | a eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a art2 swepub-publicationtype |
| 100 | 1 | a Narula, N.4 aut |
| 245 | 1 0 | a Association of ultra-processed food intake with risk of inflammatory bowel disease: prospective cohort study |
| 264 | c 2021-07-14 | |
| 264 | 1 | b BMJ,c 2021 |
| 520 | a OBJECTIVE To evaluate the relation between intake of ultra processed food and risk of inflammatory bowel disease (IBD). DESIGN Prospective cohort study. SETTING 21 low, middle, and high income countries across seven geographical regions (Europe and North America, South America, Africa, Middle East, south Asia, South East Asia, and China). PARTICIPANTS 116 087 adults aged 35-70 years with at least one cycle of follow-up and complete baseline food frequency questionnaire (FFQ) data (country specific validated FFQs were used to document baseline dietary intake). Participants were followed prospectively at least every three years. MAIN OUTCOME MEASURES The main outcome was development of IBD, including Crohn & rsquo;s disease or ulcerative colitis. Associations between ultra-processed food intake and risk of IBD were assessed using Cox proportional hazard multivariable models. Results are presented as hazard ratios with 95% confidence intervals. RESULTS Participants were enrolled in the study between 2003 and 2016. During the median follow-up of 9.7 years (interquartile range 8.9-11.2 years), 467 participants developed incident IBD (90 with Crohn & rsquo;s disease and 377 with ulcerative colitis). After adjustment for potential confounding factors, higher intake of ultra-processed food was associated with a higher risk of incident IBD (hazard ratio 1.82, 95% confidence interval 1.22 to 2.72 for >= 5 servings/day and 1.67, 1.18 to 2.37 for 1-4 servings/day compared with <1 serving/day, P=0.006 for trend). Different subgroups of ultra-processed food, including soft drinks, refined sweetened foods, salty snacks, and processed meat, each were associated with higher hazard ratios for IBD. Results were consistent for Crohn & rsquo;s disease and ulcerative colitis with low heterogeneity. Intakes of white meat, red meat, dairy, starch, and fruit, vegetables, and legumes were not associated with incident IBD. CONCLUSIONS Higher intake of ultra-processed food was positively associated with risk of IBD. Further studies are needed to identify the contributory factors within ultra processed foods. | |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Gastroenterologi0 (SwePub)302132 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Gastroenterology and Hepatology0 (SwePub)302132 hsv//eng |
| 653 | a dose-response metaanalysis | |
| 653 | a long-term intake | |
| 653 | a ulcerative-colitis | |
| 653 | a cardiovascular-disease | |
| 653 | a crohns-disease | |
| 653 | a gut microbiota | |
| 653 | a dietary factors | |
| 653 | a protein-intake | |
| 653 | a 18 countries | |
| 653 | a epidemiology | |
| 653 | a General & Internal Medicine | |
| 700 | 1 | a Wong, E. C. L.4 aut |
| 700 | 1 | a Dehghan, M.4 aut |
| 700 | 1 | a Mente, A.4 aut |
| 700 | 1 | a Rangarajan, S.4 aut |
| 700 | 1 | a Lanas, F.4 aut |
| 700 | 1 | a Lopez-Jaramillo, P.4 aut |
| 700 | 1 | a Rohatgi, P.4 aut |
| 700 | 1 | a Lakshmi, P. V. M.4 aut |
| 700 | 1 | a Varma, R. P.4 aut |
| 700 | 1 | a Orlandini, A.4 aut |
| 700 | 1 | a Avezum, A.4 aut |
| 700 | 1 | a Wielgosz, A.4 aut |
| 700 | 1 | a Poirier, P.4 aut |
| 700 | 1 | a Almadi, M. A.4 aut |
| 700 | 1 | a Altuntas, Y.4 aut |
| 700 | 1 | a Ng, K. K.4 aut |
| 700 | 1 | a Chifamba, J.4 aut |
| 700 | 1 | a Yeates, K.4 aut |
| 700 | 1 | a Puoane, T.4 aut |
| 700 | 1 | a Khatib, R.4 aut |
| 700 | 1 | a Yusuf, R.4 aut |
| 700 | 1 | a Boström, Kristina Bengtssonu Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa,Institute of Medicine, School of Public Health and Community Medicine4 aut0 (Swepub:gu)xbenkr |
| 700 | 1 | a Zatonska, K.4 aut |
| 700 | 1 | a Iqbal, R.4 aut |
| 700 | 1 | a Liu, W. D.4 aut |
| 700 | 1 | a Zhu, Y. B.4 aut |
| 700 | 1 | a Li, S. D.4 aut |
| 700 | 1 | a Dans, A.4 aut |
| 700 | 1 | a Yusufali, A.4 aut |
| 700 | 1 | a Mohammadifard, N.4 aut |
| 700 | 1 | a Marshall, J. K.4 aut |
| 700 | 1 | a Moayyedi, P.4 aut |
| 700 | 1 | a Reinisch, W.4 aut |
| 700 | 1 | a Yusuf, S.4 aut |
| 710 | 2 | a Göteborgs universitetb Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa4 org |
| 773 | 0 | t Bmj-British Medical Journald : BMJg 374q 374x 1756-1833 |
| 856 | 4 | u https://www.bmj.com/content/bmj/374/bmj.n1554.full.pdf |
| 856 | 4 8 | u https://gup.ub.gu.se/publication/307049 |
| 856 | 4 8 | u https://doi.org/10.1136/bmj.n1554 |
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