Infective endocarditis: a diagnostic and therapeutic challenge for the new millennium.

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Fältnamn	Indikatorer	Metadata
000		03677naa a2200505 4500
001		oai:gup.ub.gu.se/285411
003		SwePub
008		240528s2000 \| \|\|\|\|\|\|\|\|\|\|\|000 \|\|eng\|
024	7	a https://gup.ub.gu.se/publication/2854112 URI
024	7	a https://doi.org/10.1080/0036554007500449082 DOI
040		a (SwePub)gu
041		a eng
042		9 SwePub
072	7	a ref2 swepub-contenttype
072	7	a art2 swepub-publicationtype
100	1	a Alestig, Kjell,d 1931u Gothenburg University,Göteborgs universitet,Institutionen för invärtesmedicin, Avdelningen för infektionssjukdomar,Institute of Internal Medicine, Dept of Infectious Diseases4 aut0 (Swepub:gu)xalekj
245	1 0	a Infective endocarditis: a diagnostic and therapeutic challenge for the new millennium.
264		c 2009-07-08
264	1	b Informa UK Limited,c 2000
520		a This review on infective endocarditis (IE) is based on clinical studies carried out in Göteborg since 1984, data obtained from a Swedish national registry of IE since 1995 and existing literature. IE is still a great challenge in medicine, although improved bacteriological and echocardiographical techniques have facilitated diagnosis. In Sweden the incidence of IE is about 6 per 100,000 inhabitants a year. During recent decades IE has changed character. Patients are older, fever is often the only major symptom and a new murmur is less frequent. Streptococci, including viridans species and staphylococci, are still the most common bacteria found. Antibiotic treatment for 4-6 weeks may reduce mortality of IE to 30-50%. For further reduction, heart surgery is necessary in 20-25% of patients in order to remove infected tissues and restore valve function. Rapid diagnosis, careful antibiotic treatment and optimal surgery may reduce mortality associated with treatment to 10%. Antibiotic treatment is still mainly empiric. Penicillin and aminoglycoside for 2 weeks only seem to be effective in uncomplicated IE caused by alpha-streptococci. Otherwise, 4 weeks of treatment is needed, but aminoglycoside treatment may be reduced to 1 week in general and 2 weeks for enterococcal infections.
650	7	a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Infektionsmedicin0 (SwePub)302092 hsv//swe
650	7	a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Infectious Medicine0 (SwePub)302092 hsv//eng
653		a Anti-Bacterial Agents
653		a therapeutic use
653		a Endocarditis
653		a Bacterial
653		a diagnosis
653		a etiology
653		a therapy
653		a Enterococcus
653		a drug effects
653		a Female
653		a Humans
653		a Male
653		a Risk Factors
653		a Staphylococcal Infections
653		a drug therapy
653		a Streptococcal Infections
653		a drug therapy
700	1	a Hogevik, Harrietu Gothenburg University,Göteborgs universitet,Institutionen för invärtesmedicin, Avdelningen för infektionssjukdomar,Institute of Internal Medicine, Dept of Infectious Diseases4 aut
700	1	a Olaison, Lars,d 1949u Gothenburg University,Göteborgs universitet,Institutionen för invärtesmedicin, Avdelningen för infektionssjukdomar,Institute of Internal Medicine, Dept of Infectious Diseases4 aut0 (Swepub:gu)xolala
710	2	a Göteborgs universitetb Institutionen för invärtesmedicin, Avdelningen för infektionssjukdomar4 org
773	0	t Scandinavian journal of infectious diseasesd : Informa UK Limitedg 32:4, s. 343-56q 32:4<343-56x 0036-5548x 1651-1980
856	4 8	u https://gup.ub.gu.se/publication/285411
856	4 8	u https://doi.org/10.1080/003655400750044908

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MEDICIN OCH HÄLSOVETENSKAP: MEDICIN OCH HÄLS ...; och Klinisk medicin; och Infektionsmedici ...

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