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Sökning: WFRF:(Brooks James D) > (2020-2024) > Risks of alcohol an...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00005417naa a2200409 4500
001oai:DiVA.org:uu-509286
003SwePub
008230823s2023 | |||||||||||000 ||eng|
009oai:lup.lub.lu.se:33de05d3-e863-439a-95a9-35a7a2495802
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-5092862 URI
0247 a https://doi.org/10.1093/jncics/pkad0462 DOI
0247 a https://lup.lub.lu.se/record/33de05d3-e863-439a-95a9-35a7a24958022 URI
040 a (SwePub)uud (SwePub)lu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Crump, Caseyu Icahn Sch Med Mt Sinai, Dept Family Med & Community Hlth & Populat Hlth Sc, New York, NY USA.;Icahn Sch Med Mt Sinai, Dept Family Med & Community Hlth & Populat Hlth Sc, One Gustave L Levy Pl,Box 1077, New York, NY 10029 USA.,Icahn School of Medicine at Mount Sinai,Virginia Commonwealth University4 aut0 (Swepub:lu)al7546ed
2451 0a Risks of alcohol and drug use disorders in prostate cancer survivors :b a national cohort study
264 1b Oxford University Press (OUP),c 2023
338 a electronic2 rdacarrier
520 a Background: Prostate cancer (PC) survivors may potentially use substances to cope with psychological distress or poorly controlled physical symptoms. Little is known, however, about the long-term risks of alcohol use disorder (AUD) or drug use disorders in men with PC.Methods: A national cohort study was conducted in Sweden of 180 189 men diagnosed with PC between 1998 and 2017 and 1 801 890 age-matched population-based control men. AUD and drug use disorders were ascertained from nationwide records through 2018. Cox regression was used to compute hazard ratios (HRs) while adjusting for sociodemographic factors and prior psychiatric disorders. Subanalyses examined differences by PC treatment from 2005 to 2017.Results: Men with high-risk PC had increased risks of both AUD (adjusted HR = 1.44, 95% confidence interval [CI] = 1.33 to 1.57) and drug use disorders (adjusted HR = 1.93, 95% CI = 1.67 to 2.24). Their AUD risk was highest in the first year and was no longer significantly elevated 5 years after PC diagnosis, whereas their drug use disorders risk remained elevated 10 years after PC diagnosis (adjusted HR = 2.26, 95% CI = 1.45 to 3.52), particularly opioid use disorder (adjusted HR = 3.07, 95% CI = 1.61 to 5.84). Those treated only with androgen-deprivation therapy had the highest risks of AUD (adjusted HR = 1.91, 95% CI = 1.62 to 2.25) and drug use disorders (adjusted HR = 2.23, 95% CI = 1.70 to 2.92). Low- or intermediate-risk PC was associated with modestly increased risks of AUD (adjusted HR = 1.38, 95% CI = 1.30 to 1.46) and drug use disorders (adjusted HR = 1.19, 95% CI = 1.06 to 1.34).Conclusions: In this large cohort, men with PC had significantly increased risks of both AUD and drug use disorders, especially those with high-risk PC and treated only with androgen-deprivation therapy. PC survivors need long-term psychosocial support and timely detection and treatment of AUD and drug use disorders.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskapx Beroendelära0 (SwePub)303092 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Health Sciencesx Substance Abuse0 (SwePub)303092 hsv//eng
7001 a Stattin, Päru Uppsala University,Uppsala universitet,Urologkirurgi4 aut0 (Swepub:uu)parst892
7001 a Brooks, James D.u Stanford Univ, Dept Urol, Sch Med, Stanford, CA USA.,Stanford University School of Medicine4 aut
7001 a Sundquist, Janu Lund University,Lunds universitet,Allmänmedicin och klinisk epidemiologi,Forskargrupper vid Lunds universitet,LUCC: Lunds universitets cancercentrum,Övriga starka forskningsmiljöer,Family Medicine and Clinical Epidemiology,Lund University Research Groups,LUCC: Lund University Cancer Centre,Other Strong Research Environments,Icahn School of Medicine at Mount Sinai4 aut0 (Swepub:lu)med-jsu
7001 a Edwards, Alexis C.u Virginia Commonwealth Univ, Dept Psychiat, Richmond, VA USA.4 aut
7001 a Sieh, Weivau Univ Texas MD Anderson Canc Ctr, Dept Epidemiol, Houston, TX USA.,University of Texas4 aut
7001 a Sundquist, Kristinau Lund University,Lunds universitet,Allmänmedicin och klinisk epidemiologi,Forskargrupper vid Lunds universitet,LUCC: Lunds universitets cancercentrum,Övriga starka forskningsmiljöer,Family Medicine and Clinical Epidemiology,Lund University Research Groups,LUCC: Lund University Cancer Centre,Other Strong Research Environments,Icahn School of Medicine at Mount Sinai4 aut0 (Swepub:lu)med-ksq
7102 a Icahn Sch Med Mt Sinai, Dept Family Med & Community Hlth & Populat Hlth Sc, New York, NY USA.;Icahn Sch Med Mt Sinai, Dept Family Med & Community Hlth & Populat Hlth Sc, One Gustave L Levy Pl,Box 1077, New York, NY 10029 USA.b Icahn School of Medicine at Mount Sinai4 org
7730 t JNCI CANCER SPECTRUMd : Oxford University Press (OUP)g 7:4q 7:4x 2515-5091
8564 u https://uu.diva-portal.org/smash/get/diva2:1790469/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print
8564 u http://dx.doi.org/10.1093/jncics/pkad046x freey FULLTEXT
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-509286
8564 8u https://doi.org/10.1093/jncics/pkad046
8564 8u https://lup.lub.lu.se/record/33de05d3-e863-439a-95a9-35a7a2495802

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