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Review article: A practical approach to persistent gastrointestinal symptoms in inflammatory bowel disease in remission

Aliu, Arta (författare)
Bosch, Daan H. C. A. (författare)
Keszthelyi, Daniel (författare)
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Ardabili, Ashkan Rezazadeh (författare)
Colombel, Jean-Frederic (författare)
Sawyer, Rachel (författare)
Törnblom, Hans, 1966 (författare)
Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine
Hart, Ailsa (författare)
Jonkers, Daisy M. A. E. (författare)
Pierik, Marieke J. (författare)
Mujagic, Zlatan (författare)
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 (creator_code:org_t)
2024
2024
Engelska.
Ingår i: ALIMENTARY PHARMACOLOGY & THERAPEUTICS. - 0269-2813 .- 1365-2036. ; 59:12, s. 1470-1488
Relaterad länk:
https://gup.ub.gu.se...
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https://doi.org/10.1...
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  • Forskningsöversikt (refereegranskat)
Abstract Ämnesord
Stäng  
  • BackgroundPersistent gastrointestinal symptoms are prevalent in adult patients with inflammatory bowel disease (IBD), even when endoscopic remission is reached. These symptoms can have profound negative effects on the quality of life of affected patients and can be difficult to treat. They may be caused by IBD-related complications or comorbid disorders, but they can also be explained by irritable bowel syndrome (IBS)-like symptoms.AimsTo provide a practical step-by-step guide to diagnose and treat persistent gastrointestinal symptoms in patients with IBD in remission via a personalised approach.MethodsWe scrutinised relevant literature on causes, diagnostics and treatment of persistent gastrointestinal symptoms (abdominal pain or discomfort, bloating, abdominal distension, diarrhoea, constipation and faecal incontinence) in patients with IBD in remission.ResultsA graphical practical guide for several steps in diagnosing, identifying potential triggers and adequate treatment of persistent gastrointestinal symptoms in IBD in remission is provided based on supporting literature. The first part of this review focuses on the diagnostic and treatment approaches for potential IBD-related complications and comorbidities. The second part describes the approach to IBS-like symptoms in IBD in remission.ConclusionsPersistent gastrointestinal symptoms in IBD in remission can be traced back to potential pathophysiological mechanisms in individual patients and can be treated adequately. For both IBD-related complications and comorbidities and IBS-like symptoms in IBD in remission, pharmacological, dietary, lifestyle or psychological treatments can be effective. A systematic and personalised approach is required to reduce the burden for patients, healthcare systems, and society.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Gastroenterologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Gastroenterology and Hepatology (hsv//eng)

Nyckelord

abdominal pain
bloating
constipation
diarrhoea
IBD in remission
IBS in IBD
IBS-like symptoms

Publikations- och innehållstyp

ref (ämneskategori)
for (ämneskategori)

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