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WFRF:(Lazar Alexander J)
 

Sökning: WFRF:(Lazar Alexander J) > PED in 2021 : A maj...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00006781naa a2200793 4500
001oai:lup.lub.lu.se:0790a52f-a49a-4ce1-8689-4191f21881f2
003SwePub
008211012s2021 | |||||||||||000 ||eng|
0247 a https://lup.lub.lu.se/record/0790a52f-a49a-4ce1-8689-4191f21881f22 URI
0247 a https://doi.org/10.1093/nar/gkaa10212 DOI
040 a (SwePub)lu
041 a engb eng
042 9 SwePub
072 7a art2 swepub-publicationtype
072 7a ref2 swepub-contenttype
1001 a Lazar, Tamasu Flanders Interuniversity Institute for Biotechnology,Vrije Universiteit Brussel (VUB)4 aut
2451 0a PED in 2021 : A major update of the protein ensemble database for intrinsically disordered proteins
264 c 2020-12-10
264 1b Oxford University Press (OUP),c 2021
300 a 8 s.
520 a The Protein Ensemble Database (PED) (https://proteinensemble.org), which holds structural ensembles of intrinsically disordered proteins (IDPs), has been significantly updated and upgraded since its last release in 2016. The new version, PED 4.0, has been completely redesigned and reimplemented with cutting-edge technology and now holds about six times more data (162 versus 24 entries and 242 versus 60 structural ensembles) and a broader representation of state of the art ensemble generation methods than the previous version. The database has a completely renewed graphical interface with an interactive feature viewer for region-based annotations, and provides a series of descriptors of the qualitative and quantitative properties of the ensembles. High quality of the data is guaranteed by a new submission process, which combines both automatic and manual evaluation steps. A team of biocurators integrate structured metadata describing the ensemble generation methodology, experimental constraints and conditions. A new search engine allows the user to build advanced queries and search all entry fields including cross-references to IDP-related resources such as DisProt, MobiDB, BMRB and SASBDB. We expect that the renewed PED will be useful for researchers interested in the atomic-level understanding of IDP function, and promote the rational, structure-based design of IDP-targeting drugs.
650 7a NATURVETENSKAPx Kemix Teoretisk kemi0 (SwePub)104072 hsv//swe
650 7a NATURAL SCIENCESx Chemical Sciencesx Theoretical Chemistry0 (SwePub)104072 hsv//eng
7001 a Martínez-Pérez, Elizabethu Fundación Instituto Leloir,European Molecular Biology Laboratory Heidelberg4 aut
7001 a Quaglia, Federicau University of Padova4 aut
7001 a Hatos, Andrásu University of Padova4 aut
7001 a Chemes, Lucía B.u National University of General San Martín4 aut
7001 a Iserte, Javier A.u Fundación Instituto Leloir4 aut
7001 a Méndez, Nicolás A.u National University of General San Martín4 aut
7001 a Garrone, Nicolás A.u National University of General San Martín4 aut
7001 a Saldaño, Tadeo E.u Quilmes National University4 aut
7001 a Marchetti, Juliau Quilmes National University4 aut
7001 a Rueda, Ana Julia Velezu Quilmes National University4 aut
7001 a Bernadó, Pauu University of Montpellier4 aut
7001 a Blackledge, Martinu University Grenoble Alpes4 aut
7001 a Cordeiro, Tiago N.u University of Montpellier,NOVA University Lisbon4 aut
7001 a Fagerberg, Ericu Lund University,Lunds universitet,Beräkningskemi,Enheten för fysikalisk och teoretisk kemi,Kemiska institutionen,Institutioner vid LTH,Lunds Tekniska Högskola,Computational Chemistry,Physical and theoretical chemistry,Department of Chemistry,Departments at LTH,Faculty of Engineering, LTH4 aut0 (Swepub:lu)er5636fa
7001 a Forman-Kay, Julie D.u University of Toronto,Hospital for Sick Children, Toronto4 aut
7001 a Fornasari, Maria S.u Quilmes National University4 aut
7001 a Gibson, Toby J.u European Molecular Biology Laboratory Heidelberg4 aut
7001 a Gomes, Gregory Neal W.u University of Toronto4 aut
7001 a Gradinaru, Claudiu C.u University of Toronto4 aut
7001 a Head-Gordon, Teresau University of California, Berkeley4 aut
7001 a Jensen, Malene Ringkjøbingu University Grenoble Alpes4 aut
7001 a Lemke, Edward A.u Johannes-Gutenberg University Mainz4 aut
7001 a Longhi, Soniau Aix-Marseille University4 aut
7001 a Marino-Buslje, Cristinau Fundación Instituto Leloir4 aut
7001 a Minervini, Giovanniu University of Padova4 aut
7001 a Mittag, Tanjau St Jude Children´s Research Hospital, Memphis4 aut
7001 a Monzon, Alexander Miguelu University of Padova4 aut
7001 a Pappu, Rohit V.u Washington University in St. Louis4 aut
7001 a Parisi, Gustavou Quilmes National University4 aut
7001 a Ricard-Blum, Sylvieu Institute for Molecular and Supramolecular Chemistry and Biochemistry (ICBMS)4 aut
7001 a Ruff, Kiersten M.u Washington University in St. Louis4 aut
7001 a Salladini, Edoardou Architecture et Fonction des Macromolécules Biologiques (AFMB)4 aut
7001 a Skepö, Marieu Lund University,Lunds universitet,Beräkningskemi,Enheten för fysikalisk och teoretisk kemi,Kemiska institutionen,Institutioner vid LTH,Lunds Tekniska Högskola,LINXS - Institute of advanced Neutron and X-ray Science,Computational Chemistry,Physical and theoretical chemistry,Department of Chemistry,Departments at LTH,Faculty of Engineering, LTH,Faculty of Engineering, LTH4 aut0 (Swepub:lu)fk1-mjo
7001 a Svergun, Dmitriu European Molecular Biology Laboratory Hamburg4 aut
7001 a Vallet, Sylvain D.u Institute for Molecular and Supramolecular Chemistry and Biochemistry (ICBMS)4 aut
7001 a Varadi, Mihalyu European Bioinformatics Institute4 aut
7001 a Tompa, Peteru Vrije Universiteit Brussel (VUB),Research Centre for Natural Sciences of the Hungarian Academy of Sciences,Flanders Interuniversity Institute for Biotechnology4 aut
7001 a Tosatto, Silvio C.E.u University of Padova4 aut
7001 a Piovesan, Damianou University of Padova4 aut
7102 a Flanders Interuniversity Institute for Biotechnologyb Vrije Universiteit Brussel (VUB)4 org
7730 t Nucleic Acids Researchd : Oxford University Press (OUP)g 49:D1, s. 404-411q 49:D1<404-411x 0305-1048x 1362-4962
8564 u https://academic.oup.com/nar/article-abstract/49/D1/D404/6030232x freey FULLTEXT
8564 u http://dx.doi.org/10.1093/nar/gkaa1021x freey FULLTEXT
8564 u https://doi.org/10.1093/nar/gkaa1021
8564 8u https://lup.lub.lu.se/record/0790a52f-a49a-4ce1-8689-4191f21881f2
8564 8u https://doi.org/10.1093/nar/gkaa1021

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