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LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00006114naa a2200757 4500
001oai:lup.lub.lu.se:04d2dcf7-6fab-4ab7-9f9d-7bf7b0a175ff
003SwePub
008190523s2017 | |||||||||||000 ||eng|
0247 a https://lup.lub.lu.se/record/04d2dcf7-6fab-4ab7-9f9d-7bf7b0a175ff2 URI
0247 a https://doi.org/10.1093/ehjcvp/pvw0492 DOI
040 a (SwePub)lu
041 a engb eng
042 9 SwePub
072 7a art2 swepub-publicationtype
072 7a ref2 swepub-contenttype
1001 a Lettino, Maddalenau Humanitas Research Hospital4 aut
2451 0a Diabetic patients with acute coronary syndromes in contemporary European registries : Characteristics and outcomes
264 c 2017-03-10
264 1b Oxford University Press (OUP),c 2017
520 a Aims Among patients with acute coronary syndromes (ACS), those with diabetes mellitus (DM) are at particularly high risk of recurrent cardiovascular events and premature death. We aimed to provide a descriptive overview of unadjusted analyses of patient characteristics, ACS management, and outcomes up to 1 year after hospital admission for an ACS/index-ACS event, in patients with DM in contemporary registries in Europe. Methods and results A total of 10 registries provided data in a systematic manner on ACS patients with DM (total n =28 899), and without DM (total n= 97 505). In the DM population, the proportion of patients with ST-Segment Elevation Myocardial Infarction (STEMI) ranged from 22.1% to 64.6% (other patients had non-ST-Segment Elevation Myocardial Infarction (NSTEMI-ACS) or unstable angina). All-cause mortality in the registries ranged from 1.4% to 9.4% in-hospital; 2.8% to 7.9% at 30 days post-discharge; 5.1% to 10.7% at 180 days post-discharge; and 3.3% to 10.5% at 1 year post-discharge. Major bleeding events were reported in up to 3.8% of patients while in hospital (8 registries); up to 1.3% at 30 days (data from two registries only), and 2.0% at 1 year (one registry only). Registries differed substantially in terms of study setting, site, patient selection, definition and schedule of endpoints, and use of various P2Y12 inhibitors. In most, but not all, registries, event rates in DM patients were higher than in patients without DM. Pooled risk ratios comparing cohorts with DM vs. no DM were in-hospital significantly higher in DM for all-cause death (1.66; 95% CI 1.42-1.94), for cardiovascular death (2.33; 1.78 - 3.03), and for major bleeding (1.35; 1.21-1.52). Conclusion These registry data from real-life clinical practice confirm a high risk for recurrent events among DM patients with ACS, with great variation across the different registries.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Endokrinologi och diabetes0 (SwePub)302052 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Endocrinology and Diabetes0 (SwePub)302052 hsv//eng
653 a Acute coronary syndromes
653 a Antiplatelets
653 a Clopidogrel
653 a Diabetes mellitus
653 a Non-ST-segment elevation
653 a Observational
653 a P2Y12 receptor inhibitors
653 a Prasugrel
653 a ST-segment elevation
653 a Ticagrelor
653 a Type 2 diabetes
653 a Unstable angina
7001 a Andell, Pontusu Lund University,Lunds universitet,Kardiologi,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Cardiology,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine,Skåne University Hospital4 aut0 (Swepub:lu)med-poa
7001 a Zeymer, Uweu Klinikum Ludwigshafen4 aut
7001 a Widimsky, Petru Charles University in Prague4 aut
7001 a Danchin, Nicolasu Paris Descartes University4 aut
7001 a Bardaji, Alfredo4 aut
7001 a Barrabes, Jose A.u Vall d'Hebron University Hospital4 aut
7001 a Cequier, Angelu Bellvitge University Hospital-IDIBELL4 aut
7001 a Claeys, Marc J.u Antwerp University Hospital4 aut
7001 a De Luca, Leonardo4 aut
7001 a Dörler, Jakob4 aut
7001 a Erlinge, Davidu Lund University,Lunds universitet,Kardiologi,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Molekylär kardiologi,Forskargrupper vid Lunds universitet,Cardiology,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine,Molecular Cardiology,Lund University Research Groups,Skåne University Hospital4 aut0 (Swepub:lu)kard-der
7001 a Erne, Paulu University of Zurich4 aut
7001 a Goldstein, Patricku University of Lille4 aut
7001 a Koul, Sasha M.u Lund University,Lunds universitet,Molekylär kardiologi,Forskargrupper vid Lunds universitet,Molecular Cardiology,Lund University Research Groups,Skåne University Hospital4 aut0 (Swepub:lu)med-sku
7001 a Lemesle, Gillesu University of Lille4 aut
7001 a Lüscher, Thomas F.u University Hospital of Zurich4 aut
7001 a Matter, Christian M.u University Hospital of Zurich4 aut
7001 a Montalescot, Gillesu Pitié-Salpêtrière University Hospital4 aut
7001 a Radovanovic, Draganau University of Zurich4 aut
7001 a Sendón, Jose Lopezu University Hospital La Paz4 aut
7001 a Tousek, Petr4 aut
7001 a Weidinger, Franzu Hospital Rudolfstiftung4 aut
7001 a Weston, Clive F.M.u Swansea University4 aut
7001 a Zaman, Azfaru Freeman Hospital4 aut
7001 a Li, Jinu University Hospital of Zurich4 aut
7001 a Jukema, J. Wouteru Leiden University Medical Centre4 aut
7102 a Humanitas Research Hospitalb Kardiologi4 org
7730 t European Heart Journal - Cardiovascular Pharmacotherapyd : Oxford University Press (OUP)g 3:4, s. 198-213q 3:4<198-213x 2055-6837x 2055-6845
8564 u http://dx.doi.org/10.1093/ehjcvp/pvw049x freey FULLTEXT
8564 u https://academic.oup.com/ehjcvp/article-pdf/3/4/198/19785227/pvw049.pdf
8564 8u https://lup.lub.lu.se/record/04d2dcf7-6fab-4ab7-9f9d-7bf7b0a175ff
8564 8u https://doi.org/10.1093/ehjcvp/pvw049

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