Search: WFRF:(Carlsson Cynthia M.) >
Measuring longitudi...
Measuring longitudinal cognition: Individual tests versus composites.
-
Jonaitis, Erin M (author)
-
Koscik, Rebecca L (author)
-
Clark, Lindsay R (author)
-
show more...
-
Ma, Yue (author)
-
Betthauser, Tobey J (author)
-
Berman, Sara E (author)
-
Allison, Samantha L (author)
-
Mueller, Kimberly D (author)
-
Hermann, Bruce P (author)
-
Van Hulle, Carol A (author)
-
Christian, Bradley T (author)
-
Bendlin, Barbara B (author)
-
- Blennow, Kaj, 1958 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi,Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry
-
- Zetterberg, Henrik, 1973 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi,Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry
-
Carlsson, Cynthia M (author)
-
Asthana, Sanjay (author)
-
Johnson, Sterling C (author)
-
show less...
-
(creator_code:org_t)
- 2018-12-14
- 2019
- English.
-
In: Alzheimer's & dementia (Amsterdam, Netherlands). - : Wiley. - 2352-8729. ; 11, s. 74-84
- Related links:
-
https://onlinelibrar...
-
show more...
-
https://gup.ub.gu.se...
-
https://doi.org/10.1...
-
show less...
Abstract
Subject headings
Close
- Longitudinal cohort studies of cognitive aging must confront several sources of within-person variability in scores. In this article, we compare several neuropsychological measures in terms of longitudinal error variance and relationships with biomarker-assessed brain amyloidosis (Aβ).Analyses used data from the Wisconsin Registry for Alzheimer's Prevention. We quantified within-person longitudinal variability and age-related trajectories for several global and domain-specific composites and their constituent scores. For a subset with cerebrospinal fluid or amyloid positron emission tomography measures, we examined how Aβ modified cognitive trajectories.Global and theoretically derived composites exhibited lower intraindividual variability and stronger age × Aβ interactions than did empirically derived composites or raw scores from single tests. For example, the theoretical executive function outperformed other executive function scores on both metrics.These results reinforce the need for careful selection of cognitive outcomes in study design, and support the emerging consensus favoring composites over single-test measures.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Neurovetenskaper (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Neurosciences (hsv//eng)
Publication and Content Type
- ref (subject category)
- art (subject category)
Find in a library
To the university's database
- By the author/editor
-
Jonaitis, Erin M
-
Koscik, Rebecca ...
-
Clark, Lindsay R
-
Ma, Yue
-
Betthauser, Tobe ...
-
Berman, Sara E
-
show more...
-
Allison, Samanth ...
-
Mueller, Kimberl ...
-
Hermann, Bruce P
-
Van Hulle, Carol ...
-
Christian, Bradl ...
-
Bendlin, Barbara ...
-
Blennow, Kaj, 19 ...
-
Zetterberg, Henr ...
-
Carlsson, Cynthi ...
-
Asthana, Sanjay
-
Johnson, Sterlin ...
-
show less...
- About the subject
-
- MEDICAL AND HEALTH SCIENCES
-
MEDICAL AND HEAL ...
-
and Basic Medicine
-
and Neurosciences
- Articles in the publication
-
Alzheimer's & de ...
- By the university
-
University of Gothenburg