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Search: WFRF:(Lilja Annika 1963) > IMPACT OF BODY WEIG...

IMPACT OF BODY WEIGHT AT AGE 20 AND WEIGHT GAIN DURING ADULTHOOD ON MIDLIFE CORONARY ARTERY CALCIUM IN 15,000 MEN AND WOMEN : AN INTERIM ANALYSIS OF THE SWEDISH CARDIOPULMONARY BIOIMAGE STUDY

Hagstrom, Emil (author)
Bergstrom, Goran (author)
Rosengren, Annika (author)
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Brolin, Elin B. (author)
Brandberg, John (author)
Cederlund, Kerstin (author)
Engstrom, Gunnar (author)
Engvall, Jan, 1953- (author)
Linköpings universitet,Medicinska fakulteten,Avdelningen för diagnostik och specialistmedicin,Region Östergötland, Fysiologiska kliniken US
Eriksson, Maria J. (author)
Goncalves, Isabel (author)
James, Stefan (author)
Jernberg, Tomas (author)
Lilja, Mikael (author)
Magnusson, Martin (author)
Persson, Anders, 1953- (author)
Linköpings universitet,Avdelningen för diagnostik och specialistmedicin,Medicinska fakulteten,Region Östergötland, Röntgenkliniken i Linköping
Persson, Margaretha (author)
Sandstrom, Anette (author)
Schmidt, Caroline (author)
Skoglund Larsson, Linn (author)
Sundstrom, Johan (author)
Swahn, Eva, 1949- (author)
Linköpings universitet,Medicinska fakulteten,Avdelningen för diagnostik och specialistmedicin,Region Östergötland, Kardiologiska kliniken US
Soderberg, Stefan (author)
Toren, Kjell (author)
Östgren, Carl Johan, 1963- (author)
Linköpings universitet,Avdelningen för prevention, rehabilitering och nära vård,Medicinska fakulteten,Region Östergötland, Vårdcentralen Ödeshög
Lind, Lars (author)
University of Gothenburg, Gothenburg, Sweden
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 (creator_code:org_t)
ELSEVIER SCIENCE INC, 2019
2019
English.
In: Journal of the American College of Cardiology. - : ELSEVIER SCIENCE INC. - 0735-1097 .- 1558-3597. ; 73:9, s. 1692-1692
Related links:
https://urn.kb.se/re...
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https://doi.org/10.1...
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  • Journal article (other academic/artistic)
Abstract Subject headings
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  • BackgroundElevated body weight in adolescence is strongly associated with early cardiovascular disease, but whether this association is traceable to weight in early adulthood, or to weight gain with subsequent high adult weight is not known. Using data from the Swedish CArdioPulmonary bioImage Study (SCAPIS), we investigated the association between weight at age 20, weight gain to midlife and coronary artery calcium score (CACS) at midlife.MethodsIn the first 15,810 participants in SCAPIS (mean age 58 years, 52% women), data on CACS at midlife, self-reported body weight at age 20 and weight at examination in SCAPIS were recorded.ResultsCACS in midlife was significantly higher with increasing weight at age 20 (p<0.001 for both sexes), and then increased with weight gain until midlife at all levels of body weight at age 20 after adjusting for age, height, smoking, alcohol intake, education level, exercise levels and LDL cholesterol. However, the association with weight gain was only significant in men (p = 0.047), not in women (p=0.474). No significant interaction was seen between weight at age 20 and midlife weight with CACS. The effect of weight at age 20 on CACS was significantly more marked in men than in women, as was the effect of weight gain (p<0.001 for both interactions).ConclusionWeight at age 20 and weight gain to midlife were both related to CACS, but much more markedly so in men than in women, indicating a generally larger effect of both early adult weight and further weight gain until midlife on CACS in men, compared to women.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Kardiologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)

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vet (subject category)
art (subject category)

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