Rhythm Control and its Relation to Symptoms During the First Two Years After Radiofrequency Ablation for Atrial Fibrillation

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Björkenheim, Anna,1980-Örebro universitet,Institutionen för medicinska vetenskaper,Department of Cardiology, Örebro University Hospital, Örebro, Sweden (författare)

Rhythm Control and its Relation to Symptoms During the First Two Years After Radiofrequency Ablation for Atrial Fibrillation

Artikel/kapitelEngelska2016

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2016-08-05
Hoboken, USA :Wiley-Blackwell Publishing Inc.2016
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LIBRIS-ID:oai:DiVA.org:oru-51530
https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-51530URI
https://doi.org/10.1111/pace.12916DOI
https://gup.ub.gu.se/publication/247604URI

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Språk:engelska
Sammanfattning på:engelska

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Ämneskategori:art swepub-publicationtype

Anmärkningar

Funding Agencies:MedtronicÖrebro heart foundationResearch Committee of Örebro University Hospital, Örebro, Sweden
Objective: To evaluate rhythm control up to two years after AF ablation and its relation to reported symptoms.Background: The implantable loop recorder (ILR) continuously records the ECG, has an automatic AF detection algorithm and a possibility for patients to activate an ECG recording during symptoms.Methods: Fifty-seven patients (mean age 57±9 years, 60% male, 88% paroxysmal AF) underwent AF ablation following ILR implantation. Device data were downloaded at the ablation and three, six, 12, 18 and 24 months after ablation.Results: Fifty-four patients completed the two-year follow-up. Thirteen (24%) patients had no AF episodes detected by ILR during follow-up. Ten of 41 patients (24%) with AF recurrence were only detected by ILR and AF recurrences were detected earlier by ILR (P<0.001). The median AF burden in patients with AF recurrence was 5.7% (IQR 0.4-14.4) and was even lower in patients with AF only detected by ILR (P = 0.001). Forty-eight % of the patients indicated symptoms via the patient activator but 33% of those recordings were not due to AF. Early AF recurrence (within 3 months) was highly associated with later AF recurrence (P<0.001). AF burden >0.5% and longest >6h before the ablation were independent predictors of AF recurrence during intermittent but not continuous monitoring.Conclusions: After AF ablation, the AF burden was low throughout the 24 months follow-up. Nevertheless, symptoms were commonly indicated but one third of patient activated recordings did not show AF. Continuous monitoring was superior to intermittent follow-up in detecting AF episodes and assessing the AF burden.Clinical trial registration: URL: http://clinicaltrials.gov. Unique Identifier: NCT00697359.

Ämnesord och genrebeteckningar

MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Kardiologi hsv//swe
MEDICAL AND HEALTH SCIENCES Clinical Medicine Cardiac and Cardiovascular Systems hsv//eng
Atrial fibrillation
catheter ablation
implantable loop recorder
monitoring
symptoms
Cardiology
Kardiologi
atrial fibrillation
catheter ablation
implantable loop recorder
monitoring
symptoms

Biuppslag (personer, institutioner, konferenser, titlar ...)

Brandes, AxelDepartment of Cardiology, Odense University Hospital, Odense, Denmark (författare)
Chemnitz, AlexanderDepartment of Cardiology, Odense University Hospital, Odense, Denmark (författare)
Magnuson, AndersFaculty of Medicine and Health, Örebro University, Örebro, Sweden,Clinical Epidemiology and Biostatistics (författare)
Edvardsson, Nils,1942Gothenburg University,Göteborgs universitet,Institutionen för medicin,Institute of Medicine(Swepub:gu)xedvni (författare)
Poçi, Dritan,1969-Örebro universitet,Institutionen för medicinska vetenskaper,Department of Cardiology, Örebro University Hospital, Örebro, Sweden(Swepub:oru)dnpi (författare)
Örebro universitetInstitutionen för medicinska vetenskaper (creator_code:org_t)

Sammanhörande titlar

Ingår i:Pacing and Clinical ElectrophysiologyHoboken, USA : Wiley-Blackwell Publishing Inc.39:9, s. 914-9250147-83891540-8159

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Av författaren/redakt...: Björkenheim, Ann ...; Brandes, Axel; Chemnitz, Alexan ...; Magnuson, Anders; Edvardsson, Nils ...; Poçi, Dritan, 19 ...

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Av lärosätet: Örebro universitet; Göteborgs universitet

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