Rhythm Control and its Relation to Symptoms During the First Two Years After Radiofrequency Ablation for Atrial Fibrillation

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Fältnamn	Indikatorer	Metadata
000		04844naa a2200577 4500
001		oai:DiVA.org:oru-51530
003		SwePub
008		160802s2016 \| \|\|\|\|\|\|\|\|\|\|\|000 \|\|eng\|
009		oai:gup.ub.gu.se/247604
024	7	a https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-515302 URI
024	7	a https://doi.org/10.1111/pace.129162 DOI
024	7	a https://gup.ub.gu.se/publication/2476042 URI
040		a (SwePub)orud (SwePub)gu
041		a engb eng
042		9 SwePub
072	7	a ref2 swepub-contenttype
072	7	a art2 swepub-publicationtype
100	1	a Björkenheim, Anna,d 1980-u Örebro universitet,Institutionen för medicinska vetenskaper,Department of Cardiology, Örebro University Hospital, Örebro, Sweden4 aut0 (Swepub:oru)anbm
245	1 0	a Rhythm Control and its Relation to Symptoms During the First Two Years After Radiofrequency Ablation for Atrial Fibrillation
264		c 2016-08-05
264	1	a Hoboken, USA :b Wiley-Blackwell Publishing Inc.c 2016
338		a print2 rdacarrier
500		a Funding Agencies:MedtronicÖrebro heart foundationResearch Committee of Örebro University Hospital, Örebro, Sweden
520		a Objective: To evaluate rhythm control up to two years after AF ablation and its relation to reported symptoms.Background: The implantable loop recorder (ILR) continuously records the ECG, has an automatic AF detection algorithm and a possibility for patients to activate an ECG recording during symptoms.Methods: Fifty-seven patients (mean age 57±9 years, 60% male, 88% paroxysmal AF) underwent AF ablation following ILR implantation. Device data were downloaded at the ablation and three, six, 12, 18 and 24 months after ablation.Results: Fifty-four patients completed the two-year follow-up. Thirteen (24%) patients had no AF episodes detected by ILR during follow-up. Ten of 41 patients (24%) with AF recurrence were only detected by ILR and AF recurrences were detected earlier by ILR (P<0.001). The median AF burden in patients with AF recurrence was 5.7% (IQR 0.4-14.4) and was even lower in patients with AF only detected by ILR (P = 0.001). Forty-eight % of the patients indicated symptoms via the patient activator but 33% of those recordings were not due to AF. Early AF recurrence (within 3 months) was highly associated with later AF recurrence (P<0.001). AF burden >0.5% and longest >6h before the ablation were independent predictors of AF recurrence during intermittent but not continuous monitoring.Conclusions: After AF ablation, the AF burden was low throughout the 24 months follow-up. Nevertheless, symptoms were commonly indicated but one third of patient activated recordings did not show AF. Continuous monitoring was superior to intermittent follow-up in detecting AF episodes and assessing the AF burden.Clinical trial registration: URL: http://clinicaltrials.gov. Unique Identifier: NCT00697359.
650	7	a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kardiologi0 (SwePub)302062 hsv//swe
650	7	a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cardiac and Cardiovascular Systems0 (SwePub)302062 hsv//eng
653		a Atrial fibrillation
653		a catheter ablation
653		a implantable loop recorder
653		a monitoring
653		a symptoms
653		a Cardiology
653		a Kardiologi
653		a atrial fibrillation
653		a catheter ablation
653		a implantable loop recorder
653		a monitoring
653		a symptoms
700	1	a Brandes, Axelu Department of Cardiology, Odense University Hospital, Odense, Denmark4 aut
700	1	a Chemnitz, Alexanderu Department of Cardiology, Odense University Hospital, Odense, Denmark4 aut
700	1	a Magnuson, Andersu Faculty of Medicine and Health, Örebro University, Örebro, Sweden,Clinical Epidemiology and Biostatistics4 aut
700	1	a Edvardsson, Nils,d 1942u Gothenburg University,Göteborgs universitet,Institutionen för medicin,Institute of Medicine4 aut0 (Swepub:gu)xedvni
700	1	a Poçi, Dritan,d 1969-u Örebro universitet,Institutionen för medicinska vetenskaper,Department of Cardiology, Örebro University Hospital, Örebro, Sweden4 aut0 (Swepub:oru)dnpi
710	2	a Örebro universitetb Institutionen för medicinska vetenskaper4 org
773	0	t Pacing and Clinical Electrophysiologyd Hoboken, USA : Wiley-Blackwell Publishing Inc.g 39:9, s. 914-925q 39:9<914-925x 0147-8389x 1540-8159
856	4	u https://doi.org/10.1111/pace.12916y Fulltext
856	4	u https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/pace.12916
856	4	u https://gup.ub.gu.se/publication/247604x primaryx freey FULLTEXT
856	4 8	u https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-51530
856	4 8	u https://doi.org/10.1111/pace.12916
856	4 8	u https://gup.ub.gu.se/publication/247604

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Av författaren/redakt...: Björkenheim, Ann ...; Brandes, Axel; Chemnitz, Alexan ...; Magnuson, Anders; Edvardsson, Nils ...; Poçi, Dritan, 19 ...

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