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Exposure to carbama...
Exposure to carbamate and neurodevelopment in children : Evidence from the SMBCS cohort in China
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- Zhang, Jiming (författare)
- School of Public Health, Key Laboratory of Public Health Safety of Ministry of Education, Collaborative Innovation Center of Social Risks Governance in Health, Fudan University, Shanghai, China
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- Guo, Jianqiu (författare)
- School of Public Health, Key Laboratory of Public Health Safety of Ministry of Education, Collaborative Innovation Center of Social Risks Governance in Health, Fudan University, Shanghai, China
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- Wu, Chunhua (författare)
- School of Public Health, Key Laboratory of Public Health Safety of Ministry of Education, Collaborative Innovation Center of Social Risks Governance in Health, Fudan University, Shanghai, China
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- Qi, Xiaojuan (författare)
- School of Public Health, Key Laboratory of Public Health Safety of Ministry of Education, Collaborative Innovation Center of Social Risks Governance in Health, Fudan University, Shanghai, China
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- Jiang, Shuai (författare)
- School of Public Health, Key Laboratory of Public Health Safety of Ministry of Education, Collaborative Innovation Center of Social Risks Governance in Health, Fudan University, Shanghai, China
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- Lu, Dasheng (författare)
- Shanghai Center for Disease Control and Prevention, Shanghai, China
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- Feng, Chao (författare)
- ai Center for Disease Control and Prevention, Shanghai, China
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- Liang, Weijiu (författare)
- Changning Center for Disease Control and Prevention, Shanghai, China
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- Chang, Xiuli (författare)
- School of Public Health, Key Laboratory of Public Health Safety of Ministry of Education, Collaborative Innovation Center of Social Risks Governance in Health, Fudan University, Shanghai, China
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- Zhang, Yubin (författare)
- School of Public Health, Key Laboratory of Public Health Safety of Ministry of Education, Collaborative Innovation Center of Social Risks Governance in Health, Fudan University, Shanghai, China
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- Cao, Yang, Associate Professor, 1972- (författare)
- Örebro universitet,Institutionen för medicinska vetenskaper,Region Örebro län,Clinical Epidemiology and Biostatistics
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- Wang, Guoquan (författare)
- Shanghai Center for Disease Control and Prevention, Shanghai, China
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- Zhou, Zhijun (författare)
- School of Public Health, Key Laboratory of Public Health Safety of Ministry of Education, Collaborative Innovation Center of Social Risks Governance in Health, Fudan University, Shanghai, China
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(creator_code:org_t)
- Academic Press, 2019
- 2019
- Engelska.
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Ingår i: Environmental Research. - : Academic Press. - 0013-9351 .- 1096-0953. ; 177
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- BACKGROUND: Carbamate pesticides exposure have been linked with adverse health effects during developmental period. Based on 377 mother-child pairs from Sheyang Mini Birth Cohort Study, the present study aimed to assess carbofuranphenol exposure of three-year-old children and explore the associations between prenatal or postnatal carbofuranphenol exposures and neurodevelopmental indicators.METHODS: Urinary carbofuranphenol concentrations were measured by gas chromatography-tandem mass spectrometry. Neural developmental quotient (DQ) of children was evaluated using Gesell Developmental Schedules. Generalized linear models were used to examine the associations between carbofuranphenol concentrations and neurodevelopment.RESULTS: Geometric mean, geometric standard deviation, median, inter quartile range of postnatal urinary carbofuranphenol concentrations were 0.653 μg/L, 9.345 μg/L, 0.413 μg/L, 0.150-1.675 μg/L, respectively. Postnatal carbofuranphenol level showed negatively significant trend in language DQ [beta (β) = -0.121; 95% confidence interval (95% CI): 0.212, -0.031; p value (p) = 0.008] and total average DQ (β = -0.059, 95% CI: 0.115, -0.003; p = 0.035). Prenatal carbofuranphenol level showed negative correlations with children's adaptive DQ (β = -0.755; 95% CI: 1.257, -0.254; p = 0.003), social DQ (β = -0.341; 95% CI: 0.656, -0.027; p = 0.032) and total average DQ (β = -0.349; 95% CI: 0.693, -0.005; p = 0.047).CONCLUSION: The results of the present study supposed children in agricultural region of China are widely exposed to carbamate pesticides, and both prenatal and postnatal exposure to carbamate pesticides may lead to neurodevelopmental effect.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Arbetsmedicin och miljömedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Occupational Health and Environmental Health (hsv//eng)
Nyckelord
- Carbamate pesticide
- Carbofuranphenol
- Neurodevelopment
- Postnatal exposure
- Prenatal exposure
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- art (ämneskategori)
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Zhang, Jiming
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Guo, Jianqiu
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Wu, Chunhua
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Qi, Xiaojuan
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Jiang, Shuai
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Lu, Dasheng
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Feng, Chao
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Liang, Weijiu
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Chang, Xiuli
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Zhang, Yubin
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Cao, Yang, Assoc ...
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Wang, Guoquan
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Zhou, Zhijun
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