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Technical challenges of working with extracellular vesicles
- Ramirez, M. I. (author)
- Amorim, M. G. (author)
- Gadelha, C. (author)
- show more...
- Milic, I. (author)
- Welsh, J. A. (author)
- Freitas, V. M. (author)
- Akbar, N. (author)
- Couch, Y. (author)
- Makin, L. (author)
- Cooke, F. (author)
- Vettore, A. L. (author)
- Batista, P. X. (author)
- Freezor, R. (author)
- Pezuk, J. A. (author)
- Rosa-Fernandes, L. (author)
- Carreira, A. C. O. (author)
- Devitt, A. (author)
- Jacobs, L. (author)
- Silva, I. T. (author)
- Coakley, G. (author)
- Nunes, D. N. (author)
- Carter, D. (author)
- Palmisano, G. (author)
- Dias-Neto, E. (author)
- show less...
- (creator_code:org_t)
- 2018
- 2018
- English.
- In: Nanoscale. - : Royal Society of Chemistry (RSC). - 2040-3364 .- 2040-3372. ; 10:3, s. 881-906
- Journal article (peer-reviewed)
Abstract
Subject headings
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- Extracellular Vesicles (EVs) are gaining interest as central players in liquid biopsies, with potential applications in diagnosis, prognosis and therapeutic guidance in most pathological conditions. These nanosized particles transmit signals determined by their protein, lipid, nucleic acid and sugar content, and the unique molecular pattern of EVs dictates the type of signal to be transmitted to recipient cells. However, their small sizes and the limited quantities that can usually be obtained from patient-derived samples pose a number of challenges to their isolation, study and characterization. These challenges and some possible options to overcome them are discussed in this review. © 2018 The Royal Society of Chemistry.
Subject headings
- TEKNIK OCH TEKNOLOGIER -- Industriell bioteknik -- Biomaterial (hsv//swe)
- ENGINEERING AND TECHNOLOGY -- Industrial Biotechnology -- Bio Materials (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinsk bioteknologi -- Biomaterialvetenskap (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Medical Biotechnology -- Biomaterials Science (hsv//eng)
- TEKNIK OCH TEKNOLOGIER -- Nanoteknik (hsv//swe)
- ENGINEERING AND TECHNOLOGY -- Nano-technology (hsv//eng)
Keyword
- Materials properties
- Nanostructured materials
- Extracellular
- Molecular patterns
- Nano-sized particles
- Pathological conditions
- Sugar content
- Technical challenges
- Nucleic acids
Publication and Content Type
- ref (subject category)
- art (subject category)
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- By the author/editor
- Ramirez, M. I.
- Amorim, M. G.
- Gadelha, C.
- Milic, I.
- Welsh, J. A.
- Freitas, V. M.
- show more...
- Nawaz, Muhammad
- Akbar, N.
- Couch, Y.
- Makin, L.
- Cooke, F.
- Vettore, A. L.
- Batista, P. X.
- Freezor, R.
- Pezuk, J. A.
- Rosa-Fernandes, ...
- Carreira, A. C. ...
- Devitt, A.
- Jacobs, L.
- Silva, I. T.
- Coakley, G.
- Nunes, D. N.
- Carter, D.
- Palmisano, G.
- Dias-Neto, E.
- show less...
- About the subject
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- ENGINEERING AND TECHNOLOGY
- ENGINEERING AND ...
- and Industrial Biote ...
- and Bio Materials
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- MEDICAL AND HEALTH SCIENCES
- MEDICAL AND HEAL ...
- and Medical Biotechn ...
- and Biomaterials Sci ...
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- ENGINEERING AND TECHNOLOGY
- ENGINEERING AND ...
- and Nano technology
- Articles in the publication
- Nanoscale
- By the university
- University of Gothenburg
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