Sökning: WFRF:(Douglas Pamela S.) > Coronary Plaque in ...
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000 | 05552naa a2200685 4500 | |
001 | oai:lup.lub.lu.se:f0f696ce-f40b-4edc-a374-a09a1071e244 | |
003 | SwePub | |
008 | 240516s2024 | |||||||||||000 ||eng| | |
024 | 7 | a https://lup.lub.lu.se/record/f0f696ce-f40b-4edc-a374-a09a1071e2442 URI |
024 | 7 | a https://doi.org/10.1016/j.jacadv.2024.1009682 DOI |
040 | a (SwePub)lu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a art2 swepub-publicationtype |
072 | 7 | a ref2 swepub-contenttype |
100 | 1 | a Karady, Juliau Semmelweis University,Massachusetts General Hospital4 aut |
245 | 1 0 | a Coronary Plaque in People With HIV vs Non-HIV Asymptomatic Community and Symptomatic Higher-Risk Populations |
264 | 1 | c 2024 |
520 | a Background: People with HIV (PWH) have a high burden of coronary plaques; however, the comparison to people without known HIV (PwoH) needs clarification. Objectives: The purpose of this study was to determine coronary plaque burden/phenotype in PWH vs PwoH. Methods: Nonstatin using participants from 3 contemporary populations without known coronary plaques with coronary CT were compared: the REPRIEVE (Randomized Trial to Prevent Vascular Events in HIV) studying PWH without cardiovascular symptoms at low-to-moderate risk (n = 755); the SCAPIS (Swedish Cardiopulmonary Bioimage Study) of asymptomatic community PwoH at low-to-intermediate cardiovascular risk (n = 23,558); and the PROMISE (Prospective Multicenter Imaging Study for Evaluation of Chest Pain) of stable chest pain PwoH (n = 2,291). The coronary plaque prevalence on coronary CT was compared, and comparisons were stratified by 10-year atherosclerotic cardiovascular disease (ASCVD) risk, age, and coronary artery calcium (CAC) presence. Results: Compared to SCAPIS and PROMISE PwoH, REPRIEVE PWH were younger (50.8 ± 5.8 vs 57.3 ± 4.3 and 60.0 ± 8.0 years; P < 0.001) and had lower ASCVD risk (5.0% ± 3.2% vs 6.0% ± 5.3% and 13.5% ± 11.0%; P < 0.001). More PWH had plaque compared to the asymptomatic cohort (48.5% vs 40.3%; P < 0.001). When stratified by ASCVD risk, PWH had more plaque compared to SCAPIS and a similar prevalence of plaque compared to PROMISE. CAC = 0 was more prevalent in PWH (REPRIEVE 65.2%; SCAPIS 61.6%; PROMISE 49.6%); among CAC = 0, plaque was more prevalent in PWH compared to the PwoH cohorts (REPRIEVE 20.8%; SCAPIS 5.4%; PROMISE 12.3%, P < 0.001). Conclusions: Asymptomatic PWH in REPRIEVE had more plaque than asymptomatic PwoH in SCAPIS but had similar prevalence to a higher-risk stable chest pain cohort in PROMISE. In PWH, CAC = 0 does not reliably exclude plaque. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kardiologi0 (SwePub)302062 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cardiac and Cardiovascular Systems0 (SwePub)302062 hsv//eng |
653 | a asymptomatic community cohort | |
653 | a cardiovascular disease | |
653 | a coronary CT angiography | |
653 | a coronary plaque | |
653 | a people with HIV | |
653 | a stable chest pain | |
700 | 1 | a Lu, Michael T.u Massachusetts General Hospital4 aut |
700 | 1 | a Bergström, Göranu Sahlgrenska Academy,Sahlgrenska University Hospital4 aut |
700 | 1 | a Mayrhofer, Thomasu Massachusetts General Hospital,University of Applied Sciences Stralsund4 aut |
700 | 1 | a Taron, Janau University Medical Center Freiburg,Massachusetts General Hospital4 aut |
700 | 1 | a Foldyna, Boreku Massachusetts General Hospital4 aut |
700 | 1 | a Paradis, Kaylau Massachusetts General Hospital4 aut |
700 | 1 | a McCallum, Sarau Massachusetts General Hospital4 aut |
700 | 1 | a Aberg, Judith A.u Icahn School of Medicine at Mount Sinai4 aut |
700 | 1 | a Currier, Judith S.u University of California, Los Angeles4 aut |
700 | 1 | a Fitch, Kathleen V.u Massachusetts General Hospital4 aut |
700 | 1 | a Fulda, Evelynne S.u Massachusetts General Hospital4 aut |
700 | 1 | a Bloomfield, Gerald S.u Duke Clinical Research Institute (DCRI)4 aut |
700 | 1 | a Overton, Edgar T.4 aut |
700 | 1 | a Lind, Larsu Uppsala University4 aut |
700 | 1 | a Östgren, Carl Johanu Linköping University4 aut |
700 | 1 | a Elvstam, Olofu Lund University,Lunds universitet,Klinisk infektionsmedicin,Forskargrupper vid Lunds universitet,Clinical infection medicine,Lund University Research Groups,Växjö Central Hospital4 aut0 (Swepub:lu)ol8873el |
700 | 1 | a Söderberg, Stefanu Umeå University4 aut |
700 | 1 | a Jernberg, Tomasu Danderyd Hospital4 aut |
700 | 1 | a Pepe, Rosalieu Cooper University Hospital, Camden4 aut |
700 | 1 | a Dubé, Michael P.u University of Southern California4 aut |
700 | 1 | a Mushatt, Davidu Tulane University School of Medicine4 aut |
700 | 1 | a Fichtenbaum, Carl J.u University of Cincinnati4 aut |
700 | 1 | a Malvestutto, Carlosu Ohio State University4 aut |
700 | 1 | a Zanni, Markella V.u Massachusetts General Hospital4 aut |
700 | 1 | a Hoffmann, Udou Massachusetts General Hospital4 aut |
700 | 1 | a Ribaudo, Heather4 aut |
700 | 1 | a Grinspoon, Steven K.u Massachusetts General Hospital4 aut |
700 | 1 | a Douglas, Pamela S.u Duke Clinical Research Institute (DCRI)4 aut |
710 | 2 | a Semmelweis Universityb Massachusetts General Hospital4 org |
773 | 0 | t JACC: Advancesg 3:6q 3:6x 2772-963X |
856 | 4 | u http://dx.doi.org/10.1016/j.jacadv.2024.100968x freey FULLTEXT |
856 | 4 8 | u https://lup.lub.lu.se/record/f0f696ce-f40b-4edc-a374-a09a1071e244 |
856 | 4 8 | u https://doi.org/10.1016/j.jacadv.2024.100968 |
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