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LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00002841naa a2200481 4500
001oai:DiVA.org:uu-207317
003SwePub
008130912s2011 | |||||||||||000 ||eng|
024a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-2073172 URI
024a https://doi.org/10.1038/ng.9112 DOI
040 a (SwePub)uu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
100a Cao, Jun4 aut
2451 0a Whole-genome sequencing of multiple Arabidopsis thaliana populations.
264 c 2011-08-28
264 1b Springer Science and Business Media LLC,c 2011
338 a print2 rdacarrier
520 a The plant Arabidopsis thaliana occurs naturally in many different habitats throughout Eurasia. As a foundation for identifying genetic variation contributing to adaptation to diverse environments, a 1001 Genomes Project to sequence geographically diverse A. thaliana strains has been initiated. Here we present the first phase of this project, based on population-scale sequencing of 80 strains drawn from eight regions throughout the species' native range. We describe the majority of common small-scale polymorphisms as well as many larger insertions and deletions in the A. thaliana pan-genome, their effects on gene function, and the patterns of local and global linkage among these variants. The action of processes other than spontaneous mutation is identified by comparing the spectrum of mutations that have accumulated since A. thaliana diverged from its closest relative 10 million years ago with the spectrum observed in the laboratory. Recent species-wide selective sweeps are rare, and potentially deleterious mutations are more common in marginal populations.
650 7a NATURVETENSKAPx Biologix Evolutionsbiologi0 (SwePub)106152 hsv//swe
650 7a NATURAL SCIENCESx Biological Sciencesx Evolutionary Biology0 (SwePub)106152 hsv//eng
700a Schneeberger, Korbinian4 aut
700a Ossowski, Stephan4 aut
700a Günther, Torsten4 aut
700a Bender, Sebastian4 aut
700a Fitz, Joffrey4 aut
700a Koenig, Daniel4 aut
700a Lanz, Christa4 aut
700a Stegle, Oliver4 aut
700a Lippert, Christoph4 aut
700a Wang, Xi4 aut
700a Ott, Felix4 aut
700a Müller, Jonas4 aut
700a Alonso-Blanco, Carlos4 aut
700a Borgwardt, Karsten4 aut
700a Schmid, Karl J4 aut
700a Weigel, Detlef4 aut
773t Nature geneticsd : Springer Science and Business Media LLCg 43:10, s. 956-63q 43:10<956-63x 1546-1718x 1061-4036
856u https://www.nature.com/articles/ng.911.pdf
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-207317
8564 8u https://doi.org/10.1038/ng.911

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