Sökning: WFRF:(Grillner L) > (1995-1999) > A prospective study...
Fältnamn | Indikatorer | Metadata |
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000 | 03129naa a2200361 4500 | |
001 | oai:DiVA.org:uu-58544 | |
003 | SwePub | |
008 | 081017s1996 | |||||||||||000 ||eng| | |
009 | oai:prod.swepub.kib.ki.se:114294401 | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-585442 URI |
024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1142944012 URI |
040 | a (SwePub)uud (SwePub)ki | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Eriksson, Britt-Marieu Uppsala universitet,Institutionen för medicinska vetenskaper4 aut |
245 | 1 0 | a A prospective study of rapid methods of detecting cytomegalovirus in the blood of renal transplant recipients in relation to patient and graft survival |
264 | 1 | c 1996 |
338 | a print2 rdacarrier | |
520 | a Eighty-five renal transplant recipients were prospectively monitored for CMV infection up to 4 months post-transplantation by virus isolation from leukocytes, CMV antigen detection (pp65) in peripheral blood leukocytes (PBL), polymerase chain reaction (PCR) of alkaline treated plasma (P-PCR), PCR of extracted DNA from PBL (L-PCR) and serology. Additionally univariate and multivariate analyses of risk factors for patient and graft survival up to 4 yr post-transplantation were performed. The incidence of CMV infection was 78% and of CMV disease 33%. Antigen detection in PBL was positive before or at onset of symptoms in 23/24 (96%) evaluable patients with CMV disease. The corresponding figures for virus isolation were 22/24 (92%), P-PCR 21/24 (88%) and for L-PCR 18/24 (75%). The percentage of negative samples in patients without CMV disease was 89% for the antigen test, 92% for L-PCR and 83% for virus isolation and P-PCR. One rapid test (antigen test, P-PCR or L-PCR) was positive at a median of 16 d before the onset of symptoms. The antigen test was generally the first rapid test to become positive. CMV disease did not affect graft survival in the multivariate analysis but was associated with decreased patient survival. | |
653 | a MEDICINE | |
653 | a MEDICIN | |
700 | 1 | a Wirgart, Benita Zweygberg4 aut |
700 | 1 | a Claesson, Kerstinu Uppsala universitet,Institutionen för kirurgiska vetenskaper,Transplantation Surgery4 aut |
700 | 1 | a Tufveson, Gunnaru Uppsala universitet,Institutionen för kirurgiska vetenskaper,Transplantation Surgery4 aut |
700 | 1 | a Magnusson, Göranu Uppsala universitet,Institutionen för medicinsk biokemi och mikrobiologi4 aut0 (Swepub:uu)gma16928 |
700 | 1 | a Totterman, Thomas H.u Uppsala universitet,Institutionen för onkologi, radiologi och klinisk immunologi,KITM4 aut0 (Swepub:uu)thomtott |
700 | 1 | a Grillner, L.u Karolinska Institutet4 aut |
710 | 2 | a Uppsala universitetb Institutionen för medicinska vetenskaper4 org |
773 | 0 | t Clinical Transplantationg 10:6 Pt 1, s. 494-502q 10:6 Pt 1<494-502x 0902-0063x 1399-0012 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-58544 |
856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:114294401 |
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