Synthesis, Crystal Structure, and Conformation of Methyl 5-O-acetyl-5-cyano-6-deoxy-2,3-O-isopropylidene-β-L-gulofuranoside

• Methyl 5-O-acetyl-5-cyano-6-deoxy-2,3-O-isopropylidene-β-L-gulofuranosidewas prepared in high yield from methyl 6-deoxy-2,3-O-isopropylidene-α-D-lyxopentodialdo-1,4-furanoside. The configuration at the C5 atom was unambiguoslyestablished by single crystal X-ray analysis of the corresponding 5-O-acetyl derivative. Theconformation of the furanose and 1,3-dioxolane rings is also discussed.

Ämnesord

NATURVETENSKAP  -- Kemi -- Organisk kemi (hsv//swe)

NATURAL SCIENCES  -- Chemical Sciences -- Organic Chemistry (hsv//eng)

Nyckelord

methyl 2

conformation

3-O-isopropylidene-beta-L-gulofuranoside

X-ray crystallography

saccharide cyanohydrins

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art (ämneskategori)

ref (ämneskategori)